Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma by AHMAD, Tanya, EISEN, Tim

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Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution by Abbosh, Christopher, Birkbak, Nicolai J, Wilson, Gareth A, Jamal-Hanjani, Mariam, Constantin, Tudor, Salari, Raheleh, Le Quesne, John, Moore, David A, Veeriah, Selvaraju, Rosenthal, Rachel, Marafioti, Teresa, Kirkizlar, Eser, Watkins, Thomas B K, McGranahan, Nicholas, Ward, Sophia, Martinson, Luke, Riley, Joan, Fraioli, Francesco, Zambrana, Francisco, Endozo, Raymondo, Bi, Wenya Linda, Fennessy, Fiona M, Sponer, Nicole, Johnson, Diana, Laycock, Joanne, Shafi, Seema, Czyzewska-Khan, Justyna, Rowan, Andrew, Chambers, Tim, Matthews, Nik, Turajlic, Samra, Hiley, Crispin, Lee, Siow Ming, Forster, Martin D, Ahmad, Tanya, Falzon, Mary, Borg, Elaine, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Hafez, Dina, Naik, Ashwini, Ganguly, Apratim, Kareht, Stephanie, Shah, Rajesh, Joseph, Leena, Crosbie, Phil A, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Oukrif, Dahmane, Akarca, Ayse U, Hartley, John A, Lowe, Helen L, Lock, Sara, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Elgar, Greg, Szallasi, Zoltan, Schwarz, Roland F, Herrero, Javier, Stewart, Aengus, Quezada, Sergio A, Peggs, Karl S, Van Loo, Peter, Dive, Caroline, Lin, C Jimmy, Rabinowitz, Matthew, Aerts, Hugo J W L, Hackshaw, Allan, Shaw, Jacqui A, Zimmermann, Bernhard G, Swanton, Charles

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Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies by Furness, Andrew J.S., Joshi, Kroopa, Rosenthal, Rachel, Ghorani, Ehsan, Spain, Lavinia, Ben Aissa, Assma, Smith, Myles, Strauss, Dirk, Hayes, Andrew, Nicol, David, Mårtensson, Linda, Harrington, Kevin, Wotherspoon, Andrew, Fernando, Archana, Chandra, Ashish, Rudman, Sarah, Varia, Mary, Polson, Alexander, Stamp, Gordon, Hill, Peter, Olsburgh, Jonathan, Lester, Jason, Attanoos, Richard, Adams, Haydn, Shaw, Jacqui, Le Quesne, John, Marshall, Hilary, Nelson, Louise, Bennett, Jonathan, Martinson, Luke, Kerr, Keith, Miller, Joy, Naidu, Babu, Langman, Gerald, Bellamy, Mary, Summers, Yvonne, Shah, Rajesh, Rammohan, Kendadai, Booton, Richard, Moss, Stuart, Idries, Faiza, Joseph, Leena, Chaturvedi, Anshuman, Marie Quinn, Anne, Doran, Helen, Waddington, Rachael, Blackhall, Fiona, Rogan, Jane, Smith, Elaine, Dive, Caroline, Brady, Ged, Chemie, Francesca, Tugwood, Jonathan, Lawrence, David, Panagiotopoulos, Nikolaos, Falzon, Mary, Borg, Elaine, Jamal-Hanjani, Mariam, Juul Birkbak, Nicolai, McGranahan, Nicholas, Goldman, Jacki, Veeriah, Raju, Johnson, Diana, Oukrif, Dahmane, Janes, Sam, Hartley, John, Kevin Stone, Richard, Denner, Tamara, Costa, Marta, Phillimore, Ben, Nye, Emma, Elgar, Greg, Al-Bakir, Maise, Navani, Neal, Gorman, Pat, MacKenzie, Mairead, Bell, Harriet, Hackshaw, Allan, Smith, Sean, Shaw, Emily, Lim, Eric, Nicholson, Andrew, Rice, Alexandra, Carlo Ronquillo, John, Mensah, Natalie, Finch, Jonathan, Lau, Kelvin, Schmid, Peter, Conibear, John, Danson, Sarah, Bury, Jonathan, Hill, Jennifer, Shackcloth, Michael, Feeney, Sarah, Asante-Siaw, Julius, Blyth, Kevin, Kirk, Alan, Pule, Martin, Turajlic, Samra, Peggs, Karl S.

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Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma by Au, Lewis, Hatipoglu, Emine, Litchfield, Kevin, Beattie, Gordon, Horswell, Stuart, Nicol, David, Mason, Robert, Del Rosario, Lyra, Edmonds, Kim, Lingard, Karla, Sarker, Sarah, Carlyle, Eleanor, Attig, Jan, Becker, Pablo D., Puccio, Ignazio, Lund, Tom, Ghorani, Ehsan, Xu, Hang, Mitchison, Miriam, Moore, David A., Proctor, Ian, Falzon, Mary, Furness, Andrew J.S., Reading, James L., Marafioti, Teresa, Abbosh, Chris, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Enfield, Katey, Huebner, Ariana, Enver, Tariq, Sinclair, Ron, Rhodes, Zoe, Moore, David, Khiroya, Reena, Ellery, Peter, Veeriah, Selvaraju, Shaw, Heather, Attard, Gert, Akther, Mita Afroza, Naceur-Lombardelli, Cristina, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Ward, Sophie, Stone, Paddy, Stirling, Caroline, Spain, Lavinia, Shum, Ben, Carlyle, Eleanor, Korteweg, Justine, Chandra, Ashish, Stewart, Ruby, Iredale, Lara-Rose, Enting, Debra, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Howlett, Sarah, Michalarea, Vasiliki, Caldas, Carlos, Fitzgerald, Rebecca, Provenzano, Elena, Cluroe, Alison, McDermott, Ultan, Tavare, Simon, Roxburgh, Patricia, Chalmers, Anthony, Fraser, Sioban, Oien, Karin, Krebs, Matt, Blackhall, Fiona, Dransfield, Jo, Le Quesne, John, Tanchel, Bruce, Langman, Gerald, Robinson, Andrew, Kerr, Amy, Middleton, Gary, Webb, Joanne, Ottensmeier, Christian, Harrison, David, Hackshaw, Allan, Ledermann, Jonathan, Sharp, Abby, Farrelly, Laura, Bridger, Hayley, Kassiotis, George, Chain, Benny, Larkin, James, Swanton, Charles, Quezada, Sergio A., Turajlic, Samra, Drake, William, Fernando, Archana, Hazell, Steve, Hill, Peter, O'Brien, Tim

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution by de Bruin, Elza C., McGranahan, Nicholas, Mitter, Richard, Salm, Max, Wedge, David C., Yates, Lucy, Jamal-Hanjani, Mariam, Shafi, Seema, Murugaesu, Nirupa, Rowan, Andrew J., Grönroos, Eva, Muhammad, Madiha A., Horswell, Stuart, Gerlinger, Marco, Varela, Ignacio, Jones, David, Marshall, John, Voet, Thierry, Van Loo, Peter, Rassl, Doris M., Rintoul, Robert C., Janes, Sam M., Lee, Siow-Ming, Forster, Martin, Ahmad, Tanya, Lawrence, David, Falzon, Mary, Capitanio, Arrigo, Harkins, Timothy T., Lee, Clarence C., Tom, Warren, Teefe, Enock, Chen, Shann-Ching, Begum, Sharmin, Rabinowitz, Adam, Phillimore, Benjamin, Spencer-Dene, Bradley, Stamp, Gordon, Szallasi, Zoltan, Matthews, Nik, Stewart, Aengus, Campbell, Peter, Swanton, Charles

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Antibodies against endogenous retroviruses promote lung cancer immunotherapy by Ng, Kevin W, Boumelha, Jesse, Enfield, Katey S S, Almagro, Jorge, Cha, Hongui, Pich, Oriol, Karasaki, Takahiro, Moore, David A, Salgado, Roberto, Sivakumar, Monica, Young, George, Molina-Arcas, Miriam, de Carné Trécesson, Sophie, Anastasiou, Panayiotis, Fendler, Annika, Au, Lewis, Shepherd, Scott T C, Martínez-Ruiz, Carlos, Puttick, Clare, Black, James R M, Watkins, Thomas B K, Kim, Hyemin, Shim, Seohee, Faulkner, Nikhil, Attig, Jan, Veeriah, Selvaraju, Magno, Neil, Ward, Sophia, Frankell, Alexander M, Al Bakir, Maise, Lim, Emilia L, Hill, Mark S, Wilson, Gareth A, Cook, Daniel E, Birkbak, Nicolai J, Behrens, Axel, Yousaf, Nadia, Popat, Sanjay, Hackshaw, Allan, Hiley, Crispin T, Litchfield, Kevin, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Larkin, James, Lee, Se-Hoon, Turajlic, Samra, Swanton, Charles, Downward, Julian, Kassiotis, George

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Out-of-hours admissions in patients treated with immune checkpoint inhibitors and their primary management with steroids by Awan, Sidra, Bharucha, Pooja, Steventon, Luke, Simpson, Helen, AHMAD, Tanya, Benafif, Sarah, Shaw, Heather, Chambers, Pinkie

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Precision thoracic oncology in the UK: a two-step NGS pathway for extended molecular profiling in NSCLC by Moore, David, Benafif, Sarah, Bennett, Philip, Argue, Stephanie, Lee, Siow-Ming, Ahmad, Tanya, Papadatos-Pastos, Dionysis, Forster, Martin

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95 Lorlatinib in advanced ALK-rearranged NSCLC – real-world experience in a UK population by Lucas, Tylan, Hassan, Heba, Sattar, Alisha, So, Alfred, Buckley, Thomas, Hunter, Sarah, Masento, Sebastian, Naureen, Sofia, Benafif, Sarah, Boleti, Ekaterina, Tarver, Kathryn, Ahmad, Tanya, Newsom-Davis, Tom, Janusweski, Adam, Shah, Riyaz, Ghosh, Sharmistha, Daniel Johnathan, Hughes

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102 Hepatitis B and HIV screening prior to first systemic anticancer therapy (SACT) in an inner-city London thoracic cancer population by Buckley, Thomas, Lucas, Tylan, Odita, Malcolm, Masento, Sebastian, Benafif, Sarah, Forster, Martin, Hiley, Crispin, Jamal-Hanjani, Mariam, Keshwani, Karim, Lee, Siow Ming, Papadatos-Pastos, Dionysis, Swanton, Charlie, Wilson, James, Ahmad, Tanya, Hughes, Daniel Johnathan

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Tracking genomic cancer evolution for precision medicine: the lung TRACERx study by Jamal-Hanjani, Mariam, Hackshaw, Alan, Ngai, Yenting, Shaw, Jacqueline, Dive, Caroline, Quezada, Sergio, Middleton, Gary, de Bruin, Elza, Le Quesne, John, Shafi, Seema, Falzon, Mary, Horswell, Stuart, Blackhall, Fiona, Khan, Iftekhar, Janes, Sam, Nicolson, Marianne, Lawrence, David, Forster, Martin, Fennell, Dean, Lee, Siow-Ming, Lester, Jason, Kerr, Keith, Muller, Salli, Iles, Natasha, Smith, Sean, Murugaesu, Nirupa, Mitter, Richard, Salm, Max, Stuart, Aengus, Matthews, Nik, Adams, Haydn, Ahmad, Tanya, Attanoos, Richard, Bennett, Jonathan, Birkbak, Nicolai Juul, Booton, Richard, Brady, Ged, Buchan, Keith, Capitano, Arrigo, Chetty, Mahendran, Cobbold, Mark, Crosbie, Philip, Davies, Helen, Denison, Alan, Djearman, Madhav, Goldman, Jacki, Haswell, Tom, Joseph, Leena, Kornaszewska, Malgorzata, Krebs, Matthew, Langman, Gerald, MacKenzie, Mairead, Millar, Joy, Morgan, Bruno, Naidu, Babu, Nonaka, Daisuke, Peggs, Karl, Pritchard, Catrin, Remmen, Hardy, Rowan, Andrew, Shah, Rajesh, Smith, Elaine, Summers, Yvonne, Taylor, Magali, Veeriah, Selvaraju, Waller, David, Wilcox, Ben, Wilcox, Maggie, Woolhouse, Ian, McGranahan, Nicholas, Swanton, Charles

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Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer by Moore, David A., Benafif, Sarah, Poskitt, Benjamin, Argue, Stephanie, Lee, Siow-Ming, Ahmad, Tanya, Papadatos-Pastos, Dionysis, Jamal-Hanjani, Mariam, Bennett, Philip, Forster, Martin D.

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Clinico-pathological features of MET exon 14 mutation positive NSCLC in the UK by Benafif, Sarah, Greystoke, Alastair, Carter, Mathew, Bulusu, Ramesh, Baijal, Shobhit, Conibear, John, Nintos, Georgios, Papadatos-Pastos, Dionysis, Ahmad, Tanya, Lee, Siow-Ming, Forster, Martin

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Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue by Litchfield, Kevin, Spain, Lavinia, Gallegos, Lisa L., Schnidrig, Desiree, Rosenbaum, Heidi, Au, Lewis, Hill, Samantha M., Thomas, Jennifer, Thompson, Lisa, Horswell, Stuart, Jones, Carol, Burgess, Daniel L., Watkins, Thomas B.K., Lim, Emilia, Birkbak, Nicolai J., Nordentoft, Iver, Pickering, Lisa, Jamal-Hanjani, Mariam, Shiu, Kai-Keen, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Papadatos-Pastos, Dionysis, Enfield, Katey, McGranahan, Nicholas, Huebner, Ariana, Parker, Peter, Walczak, Henning, Proctor, Ian, Lok, Chi-wah, Moore, David, Marafioti, Teresa, Mitchison, Miriam, Trevisan, Giorgia, Ellery, Peter, Veeriah, Selvaraju, Razaq, Maryam, Shaw, Heather, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Asghar, Uzma, Tookman, Adrian, Stirling, Caroline, Edmonds, Kim, Hunter, Nikki, Mangwende, Mary, Pearce, Karla, Yan, Haixi, Fendler, Annika, Byrne, Fiona, Popat, Sanjay, Curtis, Olivia, Toncheva, Antonia, Murra, Aida, Korteweg, Justine, Josephs, Debra, Chandra, Ashish, Spicer, James, Mahadeva, Ula, Green, Anna, Stewart, Ruby, Iredale, Lara-Rose, Mackay, Tina, Deakin, Ben, Enting, Debra, Rudman, Sarah, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Michalarea, Vasiliki, Brenton, James, Caldas, Carlos, Fitzgerald, Rebecca, Jimenez-Linan, Merche, Provenzano, Elena, Cluroe, Alison, Gilbertson, Richard, McDermott, Ultan, Tavare, Simon, Beddowes, Emma, Fraser, Sioban, Krebs, Matt, Dransfield, Jo, Le Quesne, John, Fennell, Dean, Langman, Gerald, Robinson, Andrew, Collard, Martin, Cockcroft, Peter, Ferris, Charlotte, Bancroft, Hollie, Kerr, Amy, Wilson, Rodelaine, Tomlinson, Ian, Loda, Massimo, McKenzie, Mairead, Larkin, James, Turajlic, Samra

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84 National Real World Study of Adjuvant Osimertinib in Resected EGFR Mutated Lung Cancer by Ragd Sami, Elghadi, Sabeshan, Pratheeshan, Datta, Ishita, Jha, Ayush, Abdelkhalek, Hossam, Ahmed, Samreen, Ahmad, Tanya, Anum, Sultan, Aziz, Hala, Baijal, Shobhit, Batool, Rubab, Bean, Emma, Campbell, Lynn, Cave, Judith, Cove-Smith, Laura, Dimitrakakis, Emmanouil, Evans, Joanne, Fares, Aya, Gardiner, Jill, Geldart, Tom, Gennatas, Spyros, Georgiou, Alexandras, Ghafoor, Qamar, Gilligan, David, Hall, Sally, Harrison, Imogen, Hassan, Heba, Jain, Pooja, Janjua, Tanzeel, Johnston, Edwina, Kumar, Gaurav, Kussaibati, Racha, Li, Louise, Lobo, Diana, Masento, Sebastien, McGeoch, Adam, Muller, Daniel, O'Beirne, Helen, Powell, Ceri, Shah, Riyaz, Steele, Nicola, Summers, Yvonne, Tsagkaraki, Ismini, Verissimo, Tiago, Walls, Gerard, Weir, Eleanor, Xing, Eunice, Zaki, Kam, Zlotkowski, Piotr, Newsom-Davis, Tom, Moss, Anna, Belitei, Petru, Dorey, Nicole, Earwaker, Philip, Franks, Kevin, Fraser, Ian, Greystoke, Alastair, Hughes, Daniel, Kantilal, Kavita, Mangan, Yvonne, Medley, Louise, Moss, Anna, MuthUnited Kingdomumar, Dakshinamoorthy, Peedell, Clive, Solomon, Cleo, Stevenson, Robert, Thompson, Nicola, Turnbull, Helen, Walters, Sara, Watkins, Steven

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P1.03-010 Characteristics of Lung Cancer Patients Diagnosed Following Emergency Admission: Topic: Pneumonology by Ruparel, Mamta, Ejaz, Ayesha, Chauhan, Neil, Ridge, Melanie, Chung, Donna, Forster, Martin, Janes, Sam, Newsom-Davis, Thomas, Ahmad, Tanya, Navani, Neal

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P1.03-010 Characteristics of Lung Cancer Patients Diagnosed Following Emergency Admission by Ruparel, Mamta, Ejaz, Ayesha, Chauhan, Neil, Ridge, Melanie, Chung, Donna, Forster, Martin, Janes, Sam, Newsom-Davis, Thomas, Ahmad, Tanya, Navani, Neal

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P3.02b-046 Afatinib Benefits Patients with Confirmed/Suspected EGFR Mutant NSCLC, Unsuitable for Chemotherapy (TIMELY Phase II Trial) by Popat, Sanjay, Hughes, Laura, O'Brien, Mary, Ahmad, Tanya, Lewanski, Conrad, Dernedde, Ulrike, Jankowska, Petra, Mulatero, Clive, Shah, Riyaz, Hicks, Jonathan, Geldart, Tom, Cominos, Mathilda, Gray, Gill, Spicer, James, Bell, Karen, Ngai, Yenting, Hackshaw, Allan

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P3.02b-046 Afatinib Benefits Patients with Confirmed/Suspected EGFR Mutant NSCLC, Unsuitable for Chemotherapy (TIMELY Phase II Trial): Topic: EGFR Clinical by Popat, Sanjay, Hughes, Laura, O'Brien, Mary, Ahmad, Tanya, Lewanski, Conrad, Dernedde, Ulrike, Jankowska, Petra, Mulatero, Clive, Shah, Riyaz, Hicks, Jonathan, Geldart, Tom, Cominos, Mathilda, Gray, Gill, Spicer, James, Bell, Karen, Ngai, Yenting, Hackshaw, Allan

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Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study: e1001906 by Jamal-Hanjani, Mariam, Hackshaw, Alan, Ngai, Yenting, Shaw, Jacqueline, Dive, Caroline, Quezada, Sergio, Middleton, Gary, Bruin, Elza de, Quesne, John Le, Shafi, Seema, Falzon, Mary, Horswell, Stuart, Blackhall, Fiona, Khan, Iftekhar, Janes, Sam, Nicolson, Marianne, Lawrence, David, ster, Martin, Fennell, Dean, Lee, Siow-Ming, Lester, Jason, Kerr, Keith, Muller, Salli, Iles, Natasha, Smith, Sean, Murugaesu, Nirupa, Mitter, Richard, Salm, Max, Stuart, Aengus, Matthews, Nik, Adams, Haydn, Ahmad, Tanya, Attanoos, Richard, Bennett, Jonathan, Birkbak, Nicolai Juul, Booton, Richard, Brady, Ged, Buchan, Keith, Capitano, Arrigo, Chetty, Mahendran, Cobbold, Mark, Crosbie, Philip, Davies, Helen, Denison, Alan, Djearman, Madhav, Goldman, Jacki, Haswell, Tom, Joseph, Leena, Kornaszewska, Malgorzata, Krebs, Matthew, Langman, Gerald, MacKenzie, Mairead, Millar, Joy, Morgan, Bruno, Naidu, Babu, Nonaka, Daisuke, Peggs, Karl, Pritchard, Catrin, Remmen, Hardy, Rowan, Andrew, Shah, Rajesh, Smith, Elaine, Summers, Yvonne, Taylor, Magali, Veeriah, Selvaraju, Waller, David, Wilcox, Ben, Wilcox, Maggie, Woolhouse, Ian, McGranahan, Nicholas, Swanton, Charles

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