Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial

by El-Khoueiry, Anthony B, Dr, Sangro, Bruno, MD, Yau, Thomas, MD, Crocenzi, Todd S, MD, Kudo, Masatoshi, MD, Hsu, Chiun, MD, Kim, Tae-You, MD, Choo, Su-Pin, BMBS, Trojan, Jörg, MD, Welling, Theodore H, MD, Meyer, Tim, MD, Kang, Yoon-Koo, MD, Yeo, Winnie, MD, Chopra, Akhil, MD, Anderson, Jeffrey, MD, dela Cruz, Christine, MD, Lang, Lixin, PhD, Neely, Jaclyn, PhD, Tang, Hao, PhD, Dastani, Homa B, PhD, Melero, Ignacio
Published in The Lancet (British edition)

Sepsis and septic shock

by Cecconi, Maurizio, Evans, Laura, Levy, Mitchell, Rhodes, Andrew
Published in The Lancet (British edition)

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

by Rudd, Kristina E, Johnson, Sarah Charlotte, Agesa, Kareha M, Shackelford, Katya Anne, Tsoi, Derrick, Kievlan, Daniel Rhodes, Colombara, Danny V, Ikuta, Kevin S, Kissoon, Niranjan, Finfer, Simon, Fleischmann-Struzek, Carolin, Machado, Flavia R, Reinhart, Konrad K, Rowan, Kathryn, Seymour, Christopher W, Watson, R Scott, West, T Eoin, Marinho, Fatima, Hay, Simon I, Lozano, Rafael, Lopez, Alan D, Angus, Derek C, Murray, Christopher J L, Naghavi, Mohsen
Published in The Lancet (British edition)

Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2

by Antonelli, Michela, Pujol, Joan Capdevila, Spector, Tim D, Ourselin, Sebastien, Steves, Claire J
Published in The Lancet (British edition)

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

by Folegatti, Pedro M, Bibi, Sagida, Chappell, Harry, Fedosyuk, Sofiya, Gbesemete, Diane, Kelly, Elizabeth J, Makinson, Rebecca, Rawlinson, Thomas, Ross-Russell, Amy L, Saich, Stephen, Smith, Catherine C, Tarrant, Richard, Thomas, Kelly M, Warren, Sarah C, Lambe, Teresa, Adams, Kelly, Ali, Aabidah, Allen, Lauren, Baker, Natalie, Barrett, Kelly, Bellamy, Duncan, Berg, Adam, Beveridge, Amy, Bewley, Kevin, Bijker, Else M., Boland, Elena, Bormans, Daan, Bower, Thomas, Boyd, Amy, Brenner, Tanja, Buttigieg, Karen R., Cao, Michelangelo, Chapman, David, Chelysheva, Irina, Cifuentes, Liliana, Collins, Sarah, Conlon, Christopher P., Davis, Judith, Dong, Tao, Drake, Jonathan, Fisher, Richard, Garlant, Harriet, Gavrila, Madita, Gibbons, Felicity, Gill, Hardeep, Hart, Thomas C., Hartnell, Birgit, Haskell, Louise, Hawkins, Sophia, Hermosin Herrera, Macarena, Hill, David, Hill, Jennifer, Howes, Jessica, Jackson, Susan, Joshi, Amar, Kelly, Dearbhla M., King, Lloyd D.W., Knott, Daniel, Lee, Kim Y.N., Leung, Stephanie, Liu, Shuchang, Loew, Lisa, Madhavan, Meera, Marius, Phedra, Marshall, Julia L., Martin, Jane, Moore, Maria, Morris, Susan J., O'Reilly, Peter John, Owino, Nelly, Patel, Bhumika, Patrick-Smith, Maia, Perring, James, Phillips, Daniel J., Poulton, Ian, Presland, Laura, Pulido, David, Rajapaska, Durga, Ramos Lopez, Fernando, Rollier, Christine S., Romani, Rossana, Sedik, Cynthia, Seddiqi, Samiullah, Segireddy, Rameswara R., Sharpe, Hannah R., Silva-Reyes, Laura, Smith, David J., Smith, Daniel C., Smith, Nicholas, Stockley, David, Summerton, Eloise, Szigeti, Anna, Taylor, Ursula, Tonks, Susan, Tree, Julian A., Truby, Adam, Varughese, Rachel, Woodyer, Mark, Worth, Andrew T., Yao, Xin Li
Published in The Lancet

Spike-antibody waning after second dose of BNT162b2 or ChAdOx1

by Shrotri, Madhumita, Navaratnam, Annalan M D, Nguyen, Vincent, Byrne, Thomas, Geismar, Cyril, Fragaszy, Ellen, Beale, Sarah, Fong, Wing Lam Erica, Patel, Parth, Kovar, Jana, Hayward, Andrew C, Aldridge, Robert W
Published in The Lancet (British edition)

Beware of the second wave of COVID-19

by Xu, Shunqing, Li, Yuanyuan
Published in The Lancet

Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

by Wang, Chen, Xu, Jianying, Yang, Lan, Xu, Yongjian, Zhang, Xiangyan, Bai, Chunxue, Kang, Jian, Ran, Pixin, Shen, Huahao, Wen, Fuqiang, Huang, Kewu, Yao, Wanzhen, Sun, Tieying, Shan, Guangliang, Yang, Ting, Lin, Yingxiang, Wu, Sinan, Zhu, Jianguo, Wang, Ruiying, Shi, Zhihong, Zhao, Jianping, Ye, Xianwei, Song, Yuanlin, Wang, Qiuyue, Zhou, Yumin, Ding, Liren, Yang, Ting, Chen, Yahong, Guo, Yanfei, Xiao, Fei, Lu, Yong, Peng, Xiaoxia, Zhang, Biao, Xiao, Dan, Chen, Chung-Shiuan, Wang, Zuomin, Zhang, Hong, Bu, Xiaoning, Zhang, Xiaolei, An, Li, Zhang, Shu, Cao, Zhixin, Zhan, Qingyuan, Yang, Yuanhua, Cao, Bin, Dai, Huaping, Liang, Lirong, He, Jiang
Published in The Lancet (British edition)

Lisocabtagene maraleucel versus standard of care with salvage chemotherapy followed by autologous stem cell transplantation as second-line treatment in patients with relapsed or re...

by Kamdar, Manali, Solomon, Scott R, Arnason, Jon, Johnston, Patrick B, Glass, Bertram, Bachanova, Veronika, Ibrahimi, Sami, Mielke, Stephan, Mutsaers, Pim, Hernandez-Ilizaliturri, Francisco, Izutsu, Koji, Morschhauser, Franck, Lunning, Matthew, Maloney, David G, Crotta, Alessandro, Montheard, Sandrine, Previtali, Alessandro, Stepan, Lara, Ogasawara, Ken, Mack, Timothy, Abramson, Jeremy S
Published in The Lancet (British edition)

Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, res...

by Al-Batran, Salah-Eddin, Homann, Nils, Pauligk, Claudia, Goetze, Thorsten O, Meiler, Johannes, Kasper, Stefan, Kopp, Hans-Georg, Mayer, Frank, Haag, Georg Martin, Luley, Kim, Lindig, Udo, Schmiegel, Wolff, Pohl, Michael, Stoehlmacher, Jan, Folprecht, Gunnar, Probst, Stephan, Prasnikar, Nicole, Fischbach, Wolfgang, Mahlberg, Rolf, Trojan, Jörg, Koenigsmann, Michael, Martens, Uwe M, Thuss-Patience, Peter, Egger, Matthias, Block, Andreas, Heinemann, Volker, Illerhaus, Gerald, Moehler, Markus, Schenk, Michael, Kullmann, Frank, Behringer, Dirk M, Heike, Michael, Pink, Daniel, Teschendorf, Christian, Löhr, Carmen, Bernhard, Helga, Schuch, Gunter, Rethwisch, Volker, von Weikersthal, Ludwig Fischer, Hartmann, Jörg T, Kneba, Michael, Daum, Severin, Schulmann, Karsten, Weniger, Jörg, Belle, Sebastian, Gaiser, Timo, Oduncu, Fuat S, Güntner, Martina, Hozaeel, Wael, Reichart, Alexander, Jäger, Elke, Kraus, Thomas, Mönig, Stefan, Bechstein, Wolf O, Schuler, Martin, Schmalenberg, Harald, Hofheinz, Ralf D
Published in The Lancet (British edition)

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed

by Feldmann, Marc, Maini, Ravinder N, Woody, James N, Holgate, Stephen T, Winter, Gregory, Rowland, Matthew, Richards, Duncan, Hussell, Tracy
Published in The Lancet

Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACT...

by Kang, Yoon-Koo, Boku, Narikazu, Satoh, Taroh, Ryu, Min-Hee, Chao, Yee, Kato, Ken, Chung, Hyun Cheol, Chen, Jen-Shi, Muro, Kei, Kang, Won Ki, Yeh, Kun-Huei, Yoshikawa, Takaki, Oh, Sang Cheul, Bai, Li-Yuan, Tamura, Takao, Lee, Keun-Wook, Hamamoto, Yasuo, Kim, Jong Gwang, Chin, Keisho, Oh, Do-Youn, Minashi, Keiko, Cho, Jae Yong, Tsuda, Masahiro, Chen, Li-Tzong
Published in The Lancet (British edition)

Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study

by Pollán, Marina, Pérez-Gómez, Beatriz, Pastor-Barriuso, Roberto, Oteo, Jesús, Pérez-Olmeda, Mayte, Sanmartín, Jose L, Fernández-García, Aurora, Cruz, Israel, Fernández de Larrea, Nerea, Molina, Marta, Rodríguez-Cabrera, Francisco, Martín, Mariano, Merino-Amador, Paloma, León Paniagua, Jose, Muñoz-Montalvo, Juan F, Blanco, Faustino, Yotti, Raquel, Blanco, Faustino, Gutiérrez Fernández, Rodrigo, Martín, Mariano, Mezcua Navarro, Saturnino, Molina, Marta, Muñoz-Montalvo, Juan F., Salinero Hernández, Matías, Sanmartín, Jose L., Cuenca-Estrella, Manuel, Yotti, Raquel, León Paniagua, José, Fernández de Larrea, Nerea, Fernández-Navarro, Pablo, Pastor-Barriuso, Roberto, Pollán, Marina, Avellón, Ana, Fedele, Giovanni, Fernández-García, Aurora, Oteo Iglesias, Jesús, Cruz, Israel, Fernandez Martinez, Maria Elena, Rodríguez-Cabrera, Francisco D., Hernán, Miguel A., Padrones Fernández, Susana, Rumbao Aguirre, José Manuel, Navarro Marí, José M., Palop Borrás, Begoña, Pérez Jiménez, Ana Belén, Rodríguez-Iglesias, Manuel, Calvo Gascón, Ana María, Lou Alcaine, María Luz, Donate Suárez, Ignacio, Suárez Álvarez, Oscar, Rodríguez Pérez, Mercedes, Cases Sanchís, Margarita, Carbo Saladrigas, Lluis, Hurtado Fernández, Adoración, Oliver, Antonio, Castro Feliciano, Elías, González Quintana, María Noemí, Barrasa Fernández, José María, Hernández Betancor, María Araceli, Hernández Febles, Melisa, López López, Luis-Mariano, Ugarte Miota, Teresa, De Benito Población, Inés, Celada Pérez, María Sagrario, Maté Enríquez, Tomás, Villa Arranz, Miguel, Domínguez-Gil González, Marta, Fernández-Natal, Isabel, Megías Lobón, Gregoria, Muñoz Bellido, Juan Luis, Ciruela, Pilar, Mas i Casals, Ariadna, Doladé Botías, Maria, Marcos Maeso, M. Angeles, Pérez del Campo, Dúnia, Félix de Castro, Antonio, Limón Ramírez, Ramón, Elías Retamosa, Maria Francisca, Blanco Lobeiras, María Sinda, Aguilera, Antonio, Bou, German, Caro, Yolanda, Marauri, Noemí, Soria Blanco, Luis Miguel, del Cura González, Isabel, Hernández Pascual, Montserrat, Alonso Fernández, Roberto, Merino-Amador, Paloma, Cabrera Castro, Natalia, Tomás Lizcano, Aurora, Ramírez Almagro, Cristóbal, Segovia Hernández, Manuel, Ascunce Elizaga, Nieves, Ederra Sanz, María, Ezpeleta Baquedano, Carmen, Bustinduy Bascaran, Ana, Iglesias Tamayo, Susana, Elorduy Otazua, Luis, Lopera Flores, Jesús, Vázquez de la Villa, Antonia
Published in The Lancet (British edition)

The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report

by Swinburn, Boyd A, Kraak, Vivica I, Allender, Steven, Atkins, Vincent J, Baker, Phillip I, Bogard, Jessica R, Brinsden, Hannah, Calvillo, Alejandro, De Schutter, Olivier, Devarajan, Raji, Ezzati, Majid, Friel, Sharon, Goenka, Shifalika, Hammond, Ross A, Hastings, Gerard, Hawkes, Corinna, Herrero, Mario, Hovmand, Peter S, Howden, Mark, Jaacks, Lindsay M, Kapetanaki, Ariadne B, Kasman, Matt, Kuhnlein, Harriet V, Kumanyika, Shiriki K, Larijani, Bagher, Lobstein, Tim, Long, Michael W, Matsudo, Victor K R, Mills, Susanna D H, Morgan, Gareth, Morshed, Alexandra, Nece, Patricia M, Pan, An, Patterson, David W, Sacks, Gary, Shekar, Meera, Simmons, Geoff L, Smit, Warren, Tootee, Ali, Vandevijvere, Stefanie, Waterlander, Wilma E, Wolfenden, Luke, Dietz, William H
Published in The Lancet (British edition)

Comorbidities and multi-organ injuries in the treatment of COVID-19

by Wang, Tianbing, Du, Zhe, Zhu, Fengxue, Cao, Zhaolong, An, Youzhong, Gao, Yan, Jiang, Baoguo
Published in The Lancet

On the use of corticosteroids for 2019-nCoV pneumonia

by Shang, Lianhan, Zhao, Jianping, Hu, Yi, Du, Ronghui, Cao, Bin
Published in The Lancet

2019-nCoV transmission through the ocular surface must not be ignored

by Lu, Cheng-wei, Liu, Xiu-fen, Jia, Zhi-fang
Published in The Lancet

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

by Peto, Richard, Malekzadeh, Reza, Irmansyah, Irmansyah, Kumar, Suresh, Nunes, Estevao, Tsertsvadze, Tengiz, Alonso, Ignacio, Burgui, Julieta, Caimi, Sabrina, Chalco, Angelo, Ferreyra, Roxana, Hurtado, Mariano, Laplume, Diego, Pallavicini, Cecilia, Torales, Graciela, João, Esaú, Ali, Karim, Azher, Tanweer, English, Shane, Kolan, Christophe, Schwartz, Kevin, Yansouni, Cedric, Rojas-Gambasica, Jose, Amin, Wagdi, Asem, Noha, Elshesheny, Marwa, Mohamed Gouda, Abdullah, Solyman Kabil, Mohamed, Tegegne, Netsanet Aragaw, Haukipää, Mia, Kilpeläinen, Tuomas, Rosberg, Tuomas, Sivenius, Katariina, Bounes, Fanny, Danion, Francois, Epaulard, Olivier, Gaci, Rostane, Gallien, Sebastien, Livrozet, Marine, Navellou, Jean Christoph, Quenot, Jean Pierre, Stefan, Francois, Agrawal, Nishant, Balachandran, Amith, Charan, Jaykaran, Chauhan, Nishant, Kadam, Abhijeet, Nagmani, Kammili, Roy, Dhara, Sudarsi, Ravindra Kumar, Tirupakuzhi Vijayaraghavan, Bharatkumar, Udwadia, Zarir, Arlinda, Dona, Kusuma, Indra, Mahmudji, Harli Amir, Pradana, Antonius Arditya, Afsharian, Mandana, Hashemi Madani, Shima Sadat, Hormati, Ahmad, Mousavi Anari, Seyed Alireza, Poustchi, Hossein, Shirani, Kiana, Taghizadieh, Ali, Yaghoubi, Shoeleh, Muldoon, Eavan, Sadlier, Corinna, Cauda, Roberto, Giacomazzi, Donatella, Farra, Anna, Zaidan, Nor Zaila, Berg, Åse, Heggelund, Lars, Ystrøm, Carl Magnus, Abbas, Salma, Ávila-Reyes, Pool Christopher, Flores-Valdez, Neil, Sandoval-Manrique, Hernan, Torres-Ninapayta, Walter, Awing, Arlyn, Catambing, Victor, David-Wang, Aileen, Europa, Gilly May, Gler, Maria Tarcela, Lee, Aileen, Macadato, Omar Khayyam, Villalobos, Ralph Elvi, Al Maghraby, Reem, Arribas, Jose Ramon, Chamorro Tojeiro, Sandra, de la Calle, Fernando, Diez, Cristina, Fanciulli, Chiara, Gómez Barquero, Julia, Jerusalem, Koen, Lopez Azkarreta, Iñigo, Monge-Maillo, Begoña, Nuño, Enrique, Pérez Chica, Gerardo, Pérez-López, Carmen, Schaefer, Elisabeth
Published in The Lancet (British edition)

The 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by a changing climate

by Watts, Nick, Amann, Markus, Arnell, Nigel, Ayeb-Karlsson, Sonja, Belesova, Kristine, Boykoff, Maxwell, Byass, Peter, Cai, Wenjia, Campbell-Lendrum, Diarmid, Capstick, Stuart, Chambers, Jonathan, Dalin, Carole, Daly, Meaghan, Dasandi, Niheer, Davies, Michael, Drummond, Paul, Dubrow, Robert, Ebi, Kristie L, Eckelman, Matthew, Ekins, Paul, Escobar, Luis E, Fernandez Montoya, Lucia, Georgeson, Lucien, Graham, Hilary, Haggar, Paul, Hamilton, Ian, Hartinger, Stella, Hess, Jeremy, Kelman, Ilan, Kiesewetter, Gregor, Kjellstrom, Tord, Kniveton, Dominic, Lemke, Bruno, Liu, Yang, Lott, Melissa, Lowe, Rachel, Sewe, Maquins Odhiambo, Martinez-Urtaza, Jaime, Maslin, Mark, McAllister, Lucy, McGushin, Alice, Jankin Mikhaylov, Slava, Milner, James, Moradi-Lakeh, Maziar, Morrissey, Karyn, Murray, Kris, Munzert, Simon, Nilsson, Maria, Neville, Tara, Oreszczyn, Tadj, Owfi, Fereidoon, Pearman, Olivia, Pencheon, David, Phung, Dung, Pye, Steve, Quinn, Ruth, Rabbaniha, Mahnaz, Robinson, Elizabeth, Rocklöv, Joacim, Semenza, Jan C, Sherman, Jodi, Shumake-Guillemot, Joy, Tabatabaei, Meisam, Taylor, Jonathon, Trinanes, Joaquin, Wilkinson, Paul, Costello, Anthony, Gong, Peng, Montgomery, Hugh
Published in The Lancet (British edition)

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants

by Di Cesare, Mariachiara, Bentham, James, Stevens, Gretchen A, Bjertness, Espen, Bjertness, Marius Bergsmark, Ekelund, Ulf, Graff-Iversen, Sidsel, Kolle, Elin, Krokstad, Steinar, Steene-Johannessen, Jostein
Published in The Lancet (British edition)