Multikilogram per Hour Continuous Photochemical Benzylic Brominations Applying a Smart Dimensioning Scale-up Strategy

by Steiner, Alexander, Roth, Philippe M. C., Strauss, Franz J., Gauron, Guillaume, Tekautz, Günter, Winter, Marc, Williams, Jason D., Kappe, C. Oliver
Published in Organic process research & development

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Published in Organic process research & development

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Published in Organic process research & development

Potential for the Formation of N‑Nitrosamines during the Manufacture of Active Pharmaceutical Ingredients: An Assessment of the Risk Posed by Trace Nitrite in Water

by Ashworth, Ian W, Dirat, Olivier, Teasdale, Andrew, Whiting, Matthew
Published in Organic process research & development

Heterogeneous Catalysis for Cross-Coupling Reactions: An Underutilized Powerful and Sustainable Tool in the Fine Chemical Industry?

by Vásquez-Céspedes, Suhelen, Betori, Rick C, Cismesia, Megan A, Kirsch, Janelle K, Yang, Qiang
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Light on the Horizon: Current Research and Future Perspectives in Flow Photochemistry

by Politano, Fabrizio, Oksdath-Mansilla, Gabriela
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Manufacturing Process Development for Belzutifan, Part 2: A Continuous Flow Visible-Light-Induced Benzylic Bromination

by Bottecchia, Cecilia, Lévesque, François, McMullen, Jonathan P, Ji, Yining, Reibarkh, Mikhail, Peng, Feng, Tan, Lushi, Spencer, Glenn, Nappi, Jarod, Lehnherr, Dan, Narsimhan, Karthik, Wismer, Michael K, Chen, Like, Lin, Yipeng, Dalby, Stephen M
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Development and Optimization of Liquid Chromatography Analytical Methods by Using AQbD Principles: Overview and Recent Advances

by Tome, Tim, Žigart, Nina, Časar, Zdenko, Obreza, Aleš
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A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis

by Fitzpatrick, Daniel E, Battilocchio, Claudio, Ley, Steven V
Published in Organic process research & development

N‑Butylpyrrolidinone as Alternative Solvent for Solid-Phase Peptide Synthesis

by Lopez, John, Pletscher, Stefan, Aemissegger, Andreas, Bucher, Christoph, Gallou, Fabrice
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Photoredox Iridium–Nickel Dual-Catalyzed Decarboxylative Arylation Cross-Coupling: From Batch to Continuous Flow via Self-Optimizing Segmented Flow Reactor

by Hsieh, Hsiao-Wu, Coley, Connor W, Baumgartner, Lorenz M, Jensen, Klavs F, Robinson, Richard I
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N -Nitrosodimethylamine Formation in Metformin Drug Products by the Reaction of Dimethylamine and Atmospheric NO 2

by Fukuda, Shohei, Kondo, Kanako, Fukumoto, Shoji, Takenaka, Norimichi, Uchikawa, Osamu, Yoshida, Itsuro
Published in Organic process research & development