Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment

by Yan, Victoria C, Muller, Florian L
Published in ACS Medicinal Chemistry Letters

PROTAC Technology: Opportunities and Challenges

by Gao, Hongying, Sun, Xiuyun, Rao, Yu
Published in ACS medicinal chemistry letters

Practical High-Throughput Experimentation for Chemists

by Shevlin, Michael
Published in ACS medicinal chemistry letters

In This Issue

by Fadeyi, Olugbeminiyi O.
Published in ACS medicinal chemistry letters

Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp2)–C(sp3) Cross-Coupling Methods by Library Synthesis

by Dombrowski, Amanda W, Gesmundo, Nathan J, Aguirre, Ana L, Sarris, Katerina A, Young, Jonathon M, Bogdan, Andrew R, Martin, M. Cynthia, Gedeon, Shasline, Wang, Ying
Published in ACS medicinal chemistry letters

Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-X L Inhibitor

by Wang, Le, Doherty, George A., Judd, Andrew S., Tao, Zhi-Fu, Hansen, T. Matthew, Frey, Robin R., Song, Xiaohong, Bruncko, Milan, Kunzer, Aaron R., Wang, Xilu, Wendt, Michael D., Flygare, John A., Catron, Nathaniel D., Judge, Russell A., Park, Chang H., Shekhar, Shashank, Phillips, Darren C., Nimmer, Paul, Smith, Morey L., Tahir, Stephen K., Xiao, Yu, Xue, John, Zhang, Haichao, Le, Phuong N., Mitten, Michael J., Boghaert, Erwin R., Gao, Wenqing, Kovar, Peter, Choo, Edna F., Diaz, Dolores, Fairbrother, Wayne J., Elmore, Steven W., Sampath, Deepak, Leverson, Joel D., Souers, Andrew James
Published in ACS medicinal chemistry letters

Targeting IRAK4 for Degradation with PROTACs

by Nunes, Joao, McGonagle, Grant A, Eden, Jessica, Kiritharan, Girieshanie, Touzet, Megane, Lewell, Xiao, Emery, John, Eidam, Hilary, Harling, John D, Anderson, Niall A
Published in ACS medicinal chemistry letters

Solution Conformations Shed Light on PROTAC Cell Permeability

by Atilaw, Yoseph, Poongavanam, Vasanthanathan, Svensson Nilsson, Caroline, Nguyen, Duy, Giese, Anja, Meibom, Daniel, Erdelyi, Mate, Kihlberg, Jan
Published in ACS medicinal chemistry letters

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor

by Measom, Nicholas D, Down, Kenneth D, Hirst, David J, Jamieson, Craig, Manas, Eric S, Patel, Vipulkumar K, Somers, Don O
Published in ACS medicinal chemistry letters

Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma

by Konteatis, Zenon, Artin, Erin, Nicolay, Brandon, Straley, Kimberly, Padyana, Anil K, Jin, Lei, Chen, Yue, Narayaraswamy, Rohini, Tong, Shuilong, Wang, Feng, Zhou, Ding, Cui, Dawei, Cai, Zhenwei, Luo, Zhiyong, Fang, Cheng, Tang, Huachun, Lv, Xiaobing, Nagaraja, Raj, Yang, Hua, Su, Shin-San M, Sui, Zhihua, Dang, Lenny, Yen, Katharine, Popovici-Muller, Janeta, Codega, Paolo, Campos, Carl, Mellinghoff, Ingo K, Biller, Scott A
Published in ACS medicinal chemistry letters

Issue Editorial Masthead

Published in ACS medicinal chemistry letters

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Published in ACS medicinal chemistry letters

LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

by Bonday, Zahid Q., Cortez, Guillermo S., Grogan, Michael J., Antonysamy, Stephen, Weichert, Ken, Bocchinfuso, Wayne P., Li, Fengling, Kennedy, Steven, Li, Binghui, Mader, Mary M., Arrowsmith, Cheryl H., Brown, Peter J., Eram, Mohammad S., Szewczyk, Magdalena M., Barsyte-Lovejoy, Dalia, Vedadi, Masoud, Guccione, Ernesto, Campbell, Robert M.
Published in ACS medicinal chemistry letters

Issue Publication Information

Published in ACS medicinal chemistry letters

Issue Editorial Masthead

Published in ACS medicinal chemistry letters

Issue Publication Information

Published in ACS medicinal chemistry letters

Issue Editorial Masthead

Published in ACS medicinal chemistry letters

Issue Editorial Masthead

Published in ACS medicinal chemistry letters

Issue Publication Information

Published in ACS medicinal chemistry letters

Chemical Space Profiling of SARS-CoV-2 PL pro Using DNA-Encoded Focused Libraries

by Wang, Xudong, Zhu, Ying, Zhao, Qingyi, Lu, Weiwei, Xu, Yechun, Hu, Hangchen, Lu, Xiaojie
Published in ACS medicinal chemistry letters