Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy

by Kim, Eunjung, Kim, Jae-Young, Smith, Matthew A, Haura, Eric B, Anderson, Alexander R A
Published in PLoS biology

Dose-escalated re-irradiation improves outcome in locally recurrent head and neck cancer – Results of a large multicenter analysis

by Roesch, Johannes, Oertel, Michael, Wegen, Simone, Trommer, Maike, Schleifenbaum, Julia, Hering, Dominik, Mäurer, Matthias, Knippen, Stefan, Dobiasch, Sophie, Waltenberger, Maria, von der Grün, Jens, Medenwald, Daniel, Süß, Christoph, Hoeck, Michael, Käsmann, Lukas, Fleischmann, Daniel F., Rühle, Alexander, Nicolay, Nils H., Fabian, Alexander, Löser, Anastassia, Heß, Sebastian, Tamaskovics, Bálint, Vinsensia, Maria, Hecht, Markus
Published in Radiotherapy and oncology

Financial toxicity in cancer patients undergoing radiotherapy in a universal health care system – A prospective multicenter study of 1075 patients

by Fabian, Alexander, Rühle, Alexander, Domschikowski, Justus, Trommer, Maike, Wegen, Simone, Becker, Jan-Niklas, Wurschi, Georg, Boeke, Simon, Sonnhoff, Mathias, Fink, Christoph A., Käsmann, Lukas, Schneider, Melanie, Bockelmann, Elodie, Treppner, Martin, Krug, David, Nicolay, Nils H.
Published in Radiotherapy and oncology

Psychosocial distress in cancer patients undergoing radiotherapy: a prospective national cohort of 1042 patients in Germany

by Fabian, Alexander, Rühle, Alexander, Domschikowski, Justus, Trommer, Maike, Wegen, Simone, Becker, Jan-Niklas, Wurschi, Georg, Boeke, Simon, Sonnhoff, Mathias, Fink, Christoph A., Käsmann, Lukas, Schneider, Melanie, Bockelmann, Elodie, Treppner, Martin, Mehnert-Theuerkauf, Anja, Krug, David, Nicolay, Nils H.
Published in Journal of cancer research and clinical oncology

Resistance to immune checkpoint blockade: Mechanisms, counter-acting approaches, and future directions

by Haddad, Alexander F., Young, Jacob S., Gill, Sabraj, Aghi, Manish K.
Published in Seminars in cancer biology

IDO is a nodal pathogenic driver of lung cancer and metastasis development

by Smith, Courtney, Chang, Mee Young, Parker, Katherine H, Beury, Daniel W, DuHadaway, James B, Flick, Hollie E, Boulden, Janette, Sutanto-Ward, Erika, Soler, Alejandro Peralta, Laury-Kleintop, Lisa D, Mandik-Nayak, Laura, Metz, Richard, Ostrand-Rosenberg, Suzanne, Prendergast, George C, Muller, Alexander J
Published in Cancer discovery

Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma

by Ellingson, Benjamin M, Abrey, Lauren E, Nelson, Sarah J, Kaufmann, Timothy J, Garcia, Josep, Chinot, Olivier, Saran, Frank, Nishikawa, Ryo, Henriksson, Roger, Mason, Warren P, Wick, Wolfgang, Butowski, Nicholas, Ligon, Keith L, Gerstner, Elizabeth R, Colman, Howard, de Groot, John, Chang, Susan, Mellinghoff, Ingo, Young, Robert J, Alexander, Brian M, Colen, Rivka, Taylor, Jennie W, Arrillaga-Romany, Isabel, Mehta, Arnav, Huang, Raymond Y, Pope, Whitney B, Reardon, David, Batchelor, Tracy, Prados, Michael, Galanis, Evanthia, Wen, Patrick Y, Cloughesy, Timothy F
Published in Neuro-oncology (Charlottesville, Va.)

Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group

by Karschnia, Philipp, Young, Jacob S, Dono, Antonio, Häni, Levin, Sciortino, Tommaso, Bruno, Francesco, Juenger, Stephanie T, Teske, Nico, Morshed, Ramin A, Haddad, Alexander F, Zhang, Yalan, Stoecklein, Sophia, Weller, Michael, Vogelbaum, Michael A, Beck, Juergen, Tandon, Nitin, Hervey-Jumper, Shawn, Molinaro, Annette M, Rudà, Roberta, Bello, Lorenzo, Schnell, Oliver, Esquenazi, Yoshua, Ruge, Maximilian I, Grau, Stefan J, Berger, Mitchel S, Chang, Susan M, van den Bent, Martin, Tonn, Joerg-Christian
Published in Neuro-oncology (Charlottesville, Va.)

Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naïve and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer

by Yun, Mi Ran, Kim, Dong Hwi, Kim, Seok-Young, Joo, Hyeong-Seok, Lee, You Won, Choi, Hun Mi, Park, Chae Won, Heo, Seong Gu, Kang, Han Na, Lee, Sung Sook, Schoenfeld, Adam J, Drilon, Alexander, Kang, Seok-Gu, Shim, Hyo Sup, Hong, Min Hee, Cui, J Jean, Kim, Hye Ryun, Cho, Byoung Chul
Published in Clinical cancer research

WHO Grade I Meningioma Recurrence: Identifying High Risk Patients Using Histopathological Features and the MIB-1 Index

by Haddad, Alexander F, Young, Jacob S, Kanungo, Ishan, Sudhir, Sweta, Chen, Jia-Shu, Raleigh, David R, Magill, Stephen T, McDermott, Michael W, Aghi, Manish K
Published in Frontiers in oncology

Prevalence and Clinical Implications of Epstein―Barr Virus Infection in De Novo Diffuse Large B-Cell Lymphoma in Western Countries

by CHI YOUNG OK, LING LI, YOULI ZU, BHAGAT, Govind, JIAYU CHEN, RICHARDS, Kristy L, HSI, Eric D, CHOI, William W. L, HAN VAN KRIEKEN, J, JOORYUNG HUH, WEIYUN AI, PONZONI, Maurilio, XU-MONETTE, Zijun Y, FERRERI, Andrés J. M, FARNEN, John P, MØLLER, Michael B, BUESO-RAMOS, Carlo E, MIRANDA, Roberto N, WINTER, Jane N, PIRIS, Miguel A, MEDEIROS, L. Jeffrey, YOUNG, Ken H, VISCO, Carlo, TZANKOV, Alexander, MANYAM, Ganiraju C, MONTES-MORENO, Santiago, DYBAER, Karen, CHIU, April, ORAZI, Attilio
Published in Clinical cancer research

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

by Jusakul, Apinya, Cutcutache, Ioana, Yong, Chern Han, Lim, Jing Quan, Huang, Mi Ni, Padmanabhan, Nisha, Nellore, Vishwa, Kongpetch, Sarinya, Ng, Alvin Wei Tian, Ng, Ley Moy, Choo, Su Pin, Myint, Swe Swe, Thanan, Raynoo, Nagarajan, Sanjanaa, Lim, Weng Khong, Ng, Cedric Chuan Young, Boot, Arnoud, Liu, Mo, Ong, Choon Kiat, Rajasegaran, Vikneswari, Lie, Stefanus, Lim, Alvin Soon Tiong, Lim, Tse Hui, Tan, Jing, Loh, Jia Liang, McPherson, John R, Khuntikeo, Narong, Bhudhisawasdi, Vajaraphongsa, Yongvanit, Puangrat, Wongkham, Sopit, Totoki, Yasushi, Nakamura, Hiromi, Arai, Yasuhito, Yamasaki, Satoshi, Chow, Pierce Kah-Hoe, Chung, Alexander Yaw Fui, Ooi, London Lucien Peng Jin, Lim, Kiat Hon, Dima, Simona, Duda, Dan G, Popescu, Irinel, Broet, Philippe, Hsieh, Sen-Yung, Yu, Ming-Chin, Scarpa, Aldo, Lai, Jiaming, Luo, Di-Xian, Carvalho, André Lopes, Vettore, André Luiz, Rhee, Hyungjin, Park, Young Nyun, Alexandrov, Ludmil B, Gordân, Raluca, Rozen, Steven G, Shibata, Tatsuhiro, Pairojkul, Chawalit, Teh, Bin Tean, Tan, Patrick
Published in Cancer discovery

ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

by Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.
Published in Neoplasia (New York, N.Y.)

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials

by Doebele, Robert C, Drilon, Alexander, Paz-Ares, Luis, Siena, Salvatore, Shaw, Alice T, Farago, Anna F, Blakely, Collin M, Seto, Takashi, Cho, Byung Chul, Tosi, Diego, Besse, Benjamin, Chawla, Sant P, Bazhenova, Lyudmila, Krauss, John C, Chae, Young Kwang, Barve, Minal, Garrido-Laguna, Ignacio, Liu, Stephen V, Conkling, Paul, John, Thomas, Fakih, Marwan, Sigal, Darren, Loong, Herbert H, Buchschacher, Gary L, Garrido, Pilar, Nieva, Jorge, Steuer, Conor, Overbeck, Tobias R, Bowles, Daniel W, Fox, Elizabeth, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Demetri, George D
Published in The lancet oncology

Venetoclax and Navitoclax in Combination with Chemotherapy in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

by Pullarkat, Vinod A, Lacayo, Norman J, Jabbour, Elias, Rubnitz, Jeffrey E, Bajel, Ashish, Laetsch, Theodore W, Leonard, Jessica, Colace, Susan I, Khaw, Seong Lin, Fleming, Shaun A, Mattison, Ryan J, Norris, Robin, Opferman, Joseph T, Roberts, Kathryn G, Zhao, Yaqi, Qu, Chunxu, Badawi, Mohamed, Schmidt, Michelle, Tong, Bo, Pesko, John C, Sun, Yan, Ross, Jeremy A, Vishwamitra, Deeksha, Rosenwinkel, Lindsey, Kim, Su Young, Jacobson, Amanda, Mullighan, Charles G, Alexander, Thomas B, Stock, Wendy
Published in Cancer discovery

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

by Tiriac, Hervé, Belleau, Pascal, Engle, Dannielle D, Plenker, Dennis, Deschênes, Astrid, Somerville, Tim D D, Froeling, Fieke E M, Burkhart, Richard A, Denroche, Robert E, Jang, Gun-Ho, Miyabayashi, Koji, Young, C Megan, Patel, Hardik, Ma, Michelle, LaComb, Joseph F, Palmaira, Randze Lerie D, Javed, Ammar A, Huynh, Jasmine C, Johnson, Molly, Arora, Kanika, Robine, Nicolas, Shah, Minita, Sanghvi, Rashesh, Goetz, Austin B, Lowder, Cinthya Y, Martello, Laura, Driehuis, Else, LeComte, Nicolas, Askan, Gokce, Iacobuzio-Donahue, Christine A, Clevers, Hans, Wood, Laura D, Hruban, Ralph H, Thompson, Elizabeth, Aguirre, Andrew J, Wolpin, Brian M, Sasson, Aaron, Kim, Joseph, Wu, Maoxin, Bucobo, Juan Carlos, Allen, Peter, Sejpal, Divyesh V, Nealon, William, Sullivan, James D, Winter, Jordan M, Gimotty, Phyllis A, Grem, Jean L, DiMaio, Dominick J, Buscaglia, Jonathan M, Grandgenett, Paul M, Brody, Jonathan R, Hollingsworth, Michael A, O'Kane, Grainne M, Notta, Faiyaz, Kim, Edward, Crawford, James M, Devoe, Craig, Ocean, Allyson, Wolfgang, Christopher L, Yu, Kenneth H, Li, Ellen, Vakoc, Christopher R, Hubert, Benjamin, Fischer, Sandra E, Wilson, Julie M, Moffitt, Richard, Knox, Jennifer, Krasnitz, Alexander, Gallinger, Steven, Tuveson, David A
Published in Cancer discovery

Satisfaction with radiotherapy care among cancer patients treated in Germany—secondary analysis of a large multicenter study

by Fabian, Alexander, Rühle, Alexander, Domschikowski, Justus, Trommer, Maike, Wegen, Simone, Becker, Jan-Niklas, Wurschi, Georg, Boeke, Simon, Sonnhoff, Mathias, Fink, Christoph A., Käsmann, Lukas, Schneider, Melanie, Bockelmann, Elodie, Treppner, Martin, Mehnert-Theuerkauf, Anja, Nicolay, Nils H., Krug, David
Published in Strahlentherapie und Onkologie

The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of...

by Travis, William D., Asamura, Hisao, Bankier, Alexander A., Beasley, Mary Beth, Detterbeck, Frank, Flieder, Douglas B., Goo, Jin Mo, MacMahon, Heber, Naidich, David, Nicholson, Andrew G., Powell, Charles A., Prokop, Mathias, Rami-Porta, Ramón, Rusch, Valerie, van Schil, Paul, Yatabe, Yasushi, Goldstraw, Peter, Rami-Porta, Ramón, Asamura, Hisao, Ball, David, Beer, David, Beyruti, Ricardo, Bolejack, Vanessa, Chansky, Kari, Crowley, John, Detterbeck, Frank, Eberhardt, Wilfried Ernst Erich, Edwards, John, Galateau-Sallé, Françoise, Giroux, Dorothy, Gleeson, Fergus, Groome, Patti, Huang, James, Kennedy, Catherine, Kim, Jhingook, Kim, Young Tae, Kingsbury, Laura, Kondo, Haruhiko, Krasnik, Mark, Kubota, Kaoru, Lerut, Antoon, Lyons, Gustavo, Marino, Mirella, Marom, Edith M., van Meerbeeck, Jan, Mitchell, Alan, Nakano, Takashi, Nicholson, Andrew G., Nowak, Anna, Peake, Michael, Rice, Thomas, Rosenzweig, Kenneth, Ruffini, Enrico, Rusch, Valerie, Saijo, Nagahiro, Van Schil, Paul, Sculier, Jean-Paul, Shemanski, Lynn, Stratton, Kelly, Suzuki, Kenji, Tachimori, Yuji, Thomas, Charles F., Travis, William, Tsao, Ming S., Turrisi, Andrew, Vansteenkiste, Johan, Watanabe, Hirokazu, Wu, Yi-Long, Baas, Paul, Erasmus, Jeremy, Hasegawa, Seiki, Inai, Kouki, Kernstine, Kemp, Kindler, Hedy, Krug, Lee, Nackaerts, Kristiaan, Pass, Harvey, Rice, David, Falkson, Conrad, Filosso, Pier Luigi, Giaccone, Giuseppe, Kondo, Kazuya, Lucchi, Marco, Okumura, Meinoshin, Blackstone, Eugene
Published in Journal of thoracic oncology

The role of thoracic consolidative radiotherapy in the setting of immunotherapy in extensive stage small cell lung cancer

by Verma, Saurav, Young, Sympascho, Louie, Alexander V., Palma, David, Breadner, Daniel
Published in Therapeutic Advances in Medical Oncology

Inhibition of FOXO3 Tumor Suppressor Function by βTrCP1 through Ubiquitin-Mediated Degradation in a Tumor Mouse Model

by Tsai, Wen-Bin, Chung, Young Min, Zou, Yiyu, Park, See-Hyoung, Xu, Zhaohui, Nakayama, Keiko, Lin, Sue-Hwa, Hu, Mickey C-T.
Published in PloS one