Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications

by Pasin, Chloé, Consiglio, Camila R, Huisman, Jana S, de Lange, Ann-Marie G, Peckham, Hannah, Vallejo-Yagüe, Enriqueta, Abela, Irene A, Islander, Ulrika, Neuner-Jehle, Nadia, Pujantell, Maria, Roth, Olivia, Schirmer, Melanie, Tepekule, Burcu, Zeeb, Marius, Hachfeld, Anna, Aebi-Popp, Karoline, Kouyos, Roger D, Bonhoeffer, Sebastian
Published in Royal Society open science

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

by Zhou, Bin, Di Cesare, Mariachiara, Taddei, Cristina, Stevens, Gretchen A, Khang, Young-Ho, Starc, Gregor, Abarca-Gómez, Leandra, Adams, Robert J, Aekplakorn, Wichai, Agyemang, Charles, Ajlouni, Kamel, Amouyel, Philippe, Amuzu, Antoinette, Avdicová, Mária, Balakrishna, Nagalla, Bandosz, Piotr, Barros, Mauro V G, Baur, Louise A, Benedics, Judith, Bruno, Graziella, Buoncristiano, Marta, Cacciottolo, Joseph, Chan, Angelique W, Chikova-Iscener, Ekaterina, Cifkova, Renata, Cilia, Michelle, De Curtis, Amalia, Dorosty, Ahmad Reza, Duan, Jia Li, Eggertsen, Robert, Evans, Alun, Sant'Angelo, Victoria Farrugia, Frontera, Guillermo, Gaspoz, Jean-Michel, Geiger, Harald, Giampaoli, Simona, Grodzicki, Tomasz, Grosso, Giuseppe, Gu, Dongfeng, Guimaraes, Andre L, Gurzkowska, Beata, Iacoviello, Licia, Ikram, M Arfan, Ivkovic, Vanja, Iwasaki, Masanori, Katzmarzyk, Peter T, Kelleher, Cecily, Kratzer, Wolfgang, Kumar, R Krishna, Lappas, Georg, Linneberg, Allan, Lundqvist, Annamari, Lytsy, Per, Machi, Suka, Mathiesen, Ellisiv B, Mohanna, Salim, Møller, Niels C, Mota-Pinto, Anabela, Motlagh, Mohammad Esmaeel, Muc, Magdalena, Murphy, Neil, Noale, Marianna, Ohara, Kumiko, Oliveira, Isabel O, Oltarzewski, Maciej, Ortiz, Ana P, Perez-Farinos, Napoleon, Porta, Miquel, Poulimeneas, Dimitrios, Qorbani, Mostafa, Rakhmatulloev, Sherali, Regecová, Valéria, de Wit, Tobias F Rinke, Ritti-Dias, Raphael M, Russo, Paola, Santos, Osvaldo, Saramies, Jouko L, Schargrodsky, Herman, Schmidt, Ida Maria, Sen, Abhijit, Sibai, Abla M, Sørensen, Thorkild I A, Stein, Aryeh D, Swinburn, Boyd A, Tamosiunas, Abdonas, Tell, Grethe, Tjonneland, Anne, Tuomilehto, Jaakko, Valvi, Damaskini, Varela-Moreiras, Gregorio, Veronesi, Giovanni, Visser, Marjolein, Wang, Xiangjun, Wang, Ying-Wei, Wannamethee, S Goya, Weber, Adelheid, Weghuber, Daniel, Wilks, Rainford J, Zafiropulos, Vassilis, Zholdin, Bekbolat
Published in Nature (London)

Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis

by Catton, Erin A, Bonsor, Daniel A, Herrera, Carolina, Stålhammar-Carlemalm, Margaretha, Lyndin, Mykola, Turner, Claire E, Soden, Jo, van Strijp, Jos A G, Singer, Bernhard B, van Sorge, Nina M, Lindahl, Gunnar, McCarthy, Alex J
Published in Nature communications

The role of the clinical departments for understanding patient heterogeneity in one-year mortality after a diagnosis of heart failure: A multilevel analysis of individual heterogen...

by Ghith, Nermin, Frølich, Anne, Merlo, Juan
Published in PloS one

Lung adenocarcinoma promotion by air pollutants

by Hill, William, Lim, Emilia L, Weeden, Clare E, Lee, Claudia, Augustine, Marcellus, Chen, Kezhong, Kuan, Feng-Che, Marongiu, Fabio, Evans, Jr, Edward J, Moore, David A, Rodrigues, Felipe S, Pich, Oriol, Bakker, Bjorn, Cha, Hongui, Myers, Renelle, van Maldegem, Febe, Boumelha, Jesse, Veeriah, Selvaraju, Rowan, Andrew, Naceur-Lombardelli, Cristina, Karasaki, Takahiro, Sivakumar, Monica, De, Swapnanil, Caswell, Deborah R, Nagano, Ai, Black, James R M, Martínez-Ruiz, Carlos, Ryu, Min Hyung, Huff, Ryan D, Li, Shijia, Favé, Marie-Julie, Magness, Alastair, Suárez-Bonnet, Alejandro, Priestnall, Simon L, Lüchtenborg, Margreet, Lavelle, Katrina, Pethick, Joanna, Hardy, Steven, McRonald, Fiona E, Lin, Meng-Hung, Troccoli, Clara I, Ghosh, Moumita, Miller, York E, Merrick, Daniel T, Keith, Robert L, Al Bakir, Maise, Bailey, Chris, Hill, Mark S, Saal, Lao H, Chen, Yilun, George, Anthony M, Abbosh, Christopher, Kanu, Nnennaya, Lee, Se-Hoon, McGranahan, Nicholas, Berg, Christine D, Sasieni, Peter, Houlston, Richard, Turnbull, Clare, Lam, Stephen, Awadalla, Philip, Grönroos, Eva, Downward, Julian, Jacks, Tyler, Carlsten, Christopher, Malanchi, Ilaria, Hackshaw, Allan, Litchfield, Kevin, DeGregori, James, Jamal-Hanjani, Mariam, Swanton, Charles
Published in Nature (London)

Heart age estimated using explainable advanced electrocardiography

by Lindow, Thomas, Palencia-Lamela, Israel, Schlegel, Todd T, Ugander, Martin
Published in Scientific reports

Stationary tissue background correction increases the precision of clinical evaluation of intra-cardiac shunts by cardiovascular magnetic resonance

by Nickander, Jannike, Lundin, Magnus, Abdula, Goran, Jenner, Jonas, Maret, Eva, Sörensson, Peder, Heiberg, Einar, Sigfridsson, Andreas, Ugander, Martin
Published in Scientific reports

Using visual lateralization to model learning and memory in zebrafish larvae

by Andersson, Madelene Åberg, Ek, Fredrik, Olsson, Roger
Published in Scientific reports

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

by Hendricks, Audrey E, Bochukova, Elena G, Marenne, Gaëlle, Keogh, Julia M, Atanassova, Neli, Bounds, Rebecca, Wheeler, Eleanor, Mistry, Vanisha, Henning, Elana, Körner, Antje, Muddyman, Dawn, McCarthy, Shane, Hinney, Anke, Hebebrand, Johannes, Scott, Robert A, Langenberg, Claudia, Wareham, Nick J, Surendran, Praveen, Howson, Joanna M, Butterworth, Adam S, Danesh, John, Nordestgaard, Børge G, Nielsen, Sune F, Afzal, Shoaib, Papadia, Sofia, Ashford, Sofie, Garg, Sumedha, Millhauser, Glenn L, Palomino, Rafael I, Kwasniewska, Alexandra, Tachmazidou, Ioanna, O'Rahilly, Stephen, Zeggini, Eleftheria, Barroso, Inês, Farooqi, I Sadaf
Published in Scientific reports

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

by Bonham, Luke W, Steele, Natasha Z R, Karch, Celeste M, Broce, Iris, Geier, Ethan G, Wen, Natalie L, Momeni, Parastoo, Hardy, John, Miller, Zachary A, Gorno-Tempini, Maria Luisa, Hess, Christopher P, Lewis, Patrick, Miller, Bruce L, Seeley, William W, Manzoni, Claudia, Desikan, Rahul S, Baranzini, Sergio E, Ferrari, Raffaele, Yokoyama, Jennifer S
Published in Scientific reports

Accessible and reliable neurometric testing in humans using a smartphone platform

by Boele, H J, Jung, C, Sherry, S, Roggeveen, L E M, Dijkhuizen, S, Öhman, J, Abraham, E, Uvarov, A, Boele, C P, Gultig, K, Rasmussen, A, Vinueza-Veloz, M F, Medina, J F, Koekkoek, S K E, De Zeeuw, C I, Wang, S S-H
Published in Scientific reports

The spatial RNA integrity number assay for in situ evaluation of transcriptome quality

by Kvastad, Linda, Carlberg, Konstantin, Larsson, Ludvig, Villacampa, Eva Gracia, Stuckey, Alexander, Stenbeck, Linnea, Mollbrink, Annelie, Zamboni, Margherita, Magnusson, Jens Peter, Basmaci, Elisa, Shamikh, Alia, Prochazka, Gabriela, Schaupp, Anna-Lena, Borg, Åke, Fugger, Lars, Nistér, Monica, Lundeberg, Joakim
Published in Communications biology

Optogenetic control of human neurons in organotypic brain cultures

by Andersson, My, Avaliani, Natalia, Svensson, Andreas, Wickham, Jenny, Pinborg, Lars H, Jespersen, Bo, Christiansen, Søren H, Bengzon, Johan, Woldbye, David P D, Kokaia, Merab
Published in Scientific reports

Synchrotron radiation circular dichroism spectroscopy reveals structural divergences in HDL-bound apoA-I variants

by Giudice, Rita Del, Nilsson, Oktawia, Domingo-Espín, Joan, Lagerstedt, Jens O
Published in Scientific reports

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

by Went, Molly, Sud, Amit, Försti, Asta, Halvarsson, Britt-Marie, Weinhold, Niels, Kimber, Scott, van Duin, Mark, Thorleifsson, Gudmar, Holroyd, Amy, Johnson, David C, Li, Ni, Orlando, Giulia, Law, Philip J, Ali, Mina, Chen, Bowang, Mitchell, Jonathan S, Gudbjartsson, Daniel F, Kuiper, Rowan, Stephens, Owen W, Bertsch, Uta, Broderick, Peter, Campo, Chiara, Bandapalli, Obul R, Einsele, Hermann, Gregory, Walter A, Gullberg, Urban, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H, Jöckel, Karl-Heinz, Johnsson, Ellinor, Kristinsson, Sigurður Y, Mellqvist, Ulf-Henrik, Nahi, Hareth, Easton, Douglas, Pharoah, Paul, Dunning, Alison, Peto, Julian, Canzian, Federico, Swerdlow, Anthony, Eeles, Rosalind A, Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Nickel, Jolanta, Nöthen, Markus M, Rafnar, Thorunn, Ross, Fiona M, da Silva Filho, Miguel Inacio, Thomsen, Hauke, Turesson, Ingemar, Vangsted, Annette, Andersen, Niels Frost, Waage, Anders, Walker, Brian A, Wihlborg, Anna-Karin, Broyl, Annemiek, Davies, Faith E, Thorsteinsdottir, Unnur, Langer, Christian, Hansson, Markus, Goldschmidt, Hartmut, Kaiser, Martin, Sonneveld, Pieter, Stefansson, Kari, Morgan, Gareth J, Hemminki, Kari, Nilsson, Björn, Houlston, Richard S
Published in Nature communications

Multidimensional correlation of nuclear relaxation rates and diffusion tensors for model-free investigations of heterogeneous anisotropic porous materials

by de Almeida Martins, João P, Topgaard, Daniel
Published in Scientific reports

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

by Litchfield, Kevin, Reading, James L, Lim, Emilia L, Xu, Hang, Liu, Po, Al-Bakir, Maise, Wong, Yien Ning Sophia, Rowan, Andrew, Funt, Samuel A, Merghoub, Taha, Perkins, David, Lauss, Martin, Svane, Inge Marie, Jönsson, Göran, Herrero, Javier, Larkin, James, Quezada, Sergio A, Hellmann, Matthew D, Turajlic, Samra, Swanton, Charles
Published in Nature communications

Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance

by Patel, Kashyap A, Kettunen, Jarno, Laakso, Markku, Stančáková, Alena, Laver, Thomas W, Colclough, Kevin, Johnson, Matthew B, Abramowicz, Marc, Groop, Leif, Miettinen, Päivi J, Shepherd, Maggie H, Flanagan, Sarah E, Ellard, Sian, Inagaki, Nobuya, Hattersley, Andrew T, Tuomi, Tiinamaija, Cnop, Miriam, Weedon, Michael N
Published in Nature communications

Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington's disease

by Stan, Tiberiu Loredan, Soylu-Kucharz, Rana, Burleigh, Stephen, Prykhodko, Olena, Cao, Ling, Franke, Naomi, Sjögren, Marie, Haikal, Caroline, Hållenius, Frida, Björkqvist, Maria
Published in Scientific reports

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

by Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B, Martin, Sancha, Wedge, David C, Van Loo, Peter, Ju, Young Seok, Smid, Marcel, Brinkman, Arie B, Morganella, Sandro, Aure, Miriam R, Lingjærde, Ole Christian, Langerød, Anita, Ringnér, Markus, Ahn, Sung-Min, Boyault, Sandrine, Brock, Jane E, Broeks, Annegien, Butler, Adam, Desmedt, Christine, Dirix, Luc, Dronov, Serge, Fatima, Aquila, Foekens, John A, Gerstung, Moritz, Hooijer, Gerrit K J, Jang, Se Jin, Jones, David R, Kim, Hyung-Yong, King, Tari A, Krishnamurthy, Savitri, Lee, Hee Jin, Lee, Jeong-Yeon, Li, Yilong, McLaren, Stuart, Menzies, Andrew, Mustonen, Ville, O'Meara, Sarah, Pauporté, Iris, Pivot, Xavier, Purdie, Colin A, Raine, Keiran, Ramakrishnan, Kamna, Rodríguez-González, F Germán, Romieu, Gilles, Sieuwerts, Anieta M, Simpson, Peter T, Shepherd, Rebecca, Stebbings, Lucy, Stefansson, Olafur A, Teague, Jon, Tommasi, Stefania, Treilleux, Isabelle, Van den Eynden, Gert G, Vermeulen, Peter, Vincent-Salomon, Anne, Yates, Lucy, Caldas, Carlos, van't Veer, Laura, Tutt, Andrew, Knappskog, Stian, Tan, Benita Kiat Tee, Jonkers, Jos, Borg, Åke, Ueno, Naoto T, Sotiriou, Christos, Viari, Alain, Futreal, P Andrew, Campbell, Peter J, Span, Paul N, Van Laere, Steven, Lakhani, Sunil R, Eyfjord, Jorunn E, Thompson, Alastair M, Birney, Ewan, Stunnenberg, Hendrik G, van de Vijver, Marc J, Martens, John W M, Børresen-Dale, Anne-Lise, Richardson, Andrea L, Kong, Gu, Thomas, Gilles, Stratton, Michael R
Published in Nature (London)