Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling

by Pinilla-Vera, Miguel, Xiong, Zeyu, Zhao, Yutong, Zhao, Jing, Donahoe, Michael P, Barge, Suchitra, Horne, William T, Kolls, Jay K, McVerry, Bryan J, Birukova, Anastasiya, Tighe, Robert M, Foster, W Michael, Hollingsworth, John, Ray, Anuradha, Mallampalli, Rama, Ray, Prabir, Lee, Janet S
Published in PloS one

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

by Talukdar, Saswata, Zhou, Yingjiang, Li, Dongmei, Rossulek, Michelle, Dong, Jennifer, Somayaji, Veena, Weng, Yan, Clark, Ronald, Lanba, Adhiraj, Owen, Bryn M., Brenner, Martin B., Trimmer, Jeffrey K., Gropp, Kathryn E., Chabot, Jeffrey R., Erion, Derek M., Rolph, Timothy P., Goodwin, Bryan, Calle, Roberto A.
Published in Cell metabolism

Estimates of global seasonal influenza-associated respiratory mortality: a modelling study

by Iuliano, A Danielle, Roguski, Katherine M, Chang, Howard H, Muscatello, David J, Cohen, Cheryl, Schanzer, Dena, Cowling, Benjamin J, Wu, Peng, Kyncl, Jan, Ang, Li Wei, Park, Minah, Redlberger-Fritz, Monika, Yu, Hongjie, Espenhain, Laura, Krishnan, Anand, Emukule, Gideon, van Asten, Liselotte, Pereira da Silva, Susana, Aungkulanon, Suchunya, Buchholz, Udo, Widdowson, Marc-Alain, Bresee, Joseph S, Azziz-Baumgartner, Eduardo, Cheng, Po-Yung, Dawood, Fatimah, Foppa, Ivo, Haber, Michael, MacIntyre, C Raina, Wood, James G, Kundi, Michael, Popow-Kraupp, Therese, Ahmed, Makhdum, Rahman, Mahmudur, Marinho, Fatima, Sotomayor Proschle, C Viviana, Vergara Mallegas, Natalia, Luzhao, Feng, Sa, Li, Barbosa-Ramírez, Juliana, Gomez, Leandra Abarca, Acosta Herrera, aBetsy, Llanés, María Josefa, Mølbak, Kåre, Nielsen, Jens, Trebbien, Ramona, Bruno, Alfredo, Ramos, Hector, an der Heiden, Matthias, del Carmen Castillo Signor, Leticia, Serrano, Carlos Enrique, Bhardwaj, Rohit, Chadha, Mandeep, Narayan, Venkatesh, Bromberg, Michal, Oishi, Kazunori, Nyawanda, Bryan, Matus, Cuitláhuac Ruiz, Corona, Maria Eugenia Jimenez, Burmaa, Alexander, Darmaa, Oyungerel, Cherkaoui, Imad, van den Wijngaard, Cees C, van der Hoek, Wim, Baker, Michael, Bandaranayake, Don, Huang, Sue, Grøneng, Gry M, Hauge, Siri, de Moltó, Yadira, Cabello, Maria Agueda, von Horoch, Marta, Medina Osis, Jose, Machado, Ausenda, Nunes, Baltazar, Rodrigues, Ana Paula, Lupulescu, Emilia, Popescu, Rodica, Popovici, Odette, Bogdanovic, Dragan, Lazarevic, Konstansa, Tiodorovic, Branislav, Chen, Mark, Cutter, Jeffery, Lee, Vernon, Lin, Raymond, Ma, Stefan, Cohen, Adam L, Kim, Woo Joo, Larrauri, Amparo, León, Inmaculada León, Junker, Christoph, Koch, Daniel, Huang, Wan-Ting, Kuo, Hung-Wei, Tsai, Yi-Chen, Bundhamcharoen, Kanitta, Green, Helen K, Pebody, Richard, Goñi, Natalia, Mustaquim, Desiree
Published in The Lancet (British edition)

Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

by Guièze, Romain, Liu, Vivian M., Rosebrock, Daniel, Jourdain, Alexis A., Hernández-Sánchez, María, Martinez Zurita, Aina, Sun, Jing, Ten Hacken, Elisa, Baranowski, Kaitlyn, Thompson, Philip A., Heo, Jin-Mi, Cartun, Zachary, Aygün, Ozan, Iorgulescu, J. Bryan, Zhang, Wandi, Notarangelo, Giulia, Livitz, Dimitri, Li, Shuqiang, Davids, Matthew S., Biran, Anat, Fernandes, Stacey M., Brown, Jennifer R., Lako, Ana, Ciantra, Zoe B., Lawlor, Matthew A., Keskin, Derin B., Udeshi, Namrata D., Wierda, William G., Livak, Kenneth J., Letai, Anthony G., Neuberg, Donna, Harper, J. Wade, Carr, Steven A., Piccioni, Federica, Ott, Christopher J., Leshchiner, Ignaty, Johannessen, Cory M., Doench, John, Mootha, Vamsi K., Getz, Gad, Wu, Catherine J.
Published in Cancer cell

Treat to target and prevention of subclinical atherosclerosis in psoriatic arthritis-which target should we choose?

by Cheng, Isaac T, Li, Edmund K, Wong, Priscilla C, Law, Mei Yan, Yim, Isaac C, Lai, Billy T, Ying, Shirley K, Kwok, Kitty Y, Li, Martin, Li, Tena K, Lee, Jack J, Szeto, Cheuk-Chun, Yan, Bryan P, Lee, Alex P, Tam, Lai-Shan
Published in Rheumatology (Oxford, England)

The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles

by Tarabichi, Y, Li, K, Hu, S, Nguyen, C, Wang, X, Elashoff, D, Saira, K, Frank, Bryan, Bihan, Monika, Ghedin, E, Methé, Barbara A, Deng, Jane C
Published in Microbiome

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the...

by Murray, Christopher J L, Foreman, Kyle J, Abd-Allah, Foad, Abu-Rmeileh, Niveen M, Achoki, Tom, Alla, François, Almazroa, Mohammad A, Alsharif, Ubai, Ameh, Emmanuel A, Ammar, Walid, Antonio, Carl Abelardo T, Banerjee, Amitava, Basu, Arindam, Basulaiman, Mohammed O, Beghi, Ettore, Bertozzi-Villa, Amelia, Bhala, Neeraj, Bikbov, Boris, Blyth, Fiona M, Bourne, Rupert R A, Bulchis, Anne, Chang, Jung-Chen, Coppola, Luis M, Cuevas-Nasu, Lucia, Danawi, Hadi, Dandona, Rakhi, Davey, Gail, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Deribe, Kebede, Dherani, Mukesh K, Duan, Leilei, Endres, Matthias, Erskine, Holly E, Eshrati, Babak, Felson, David T, Gessner, Bradford D, Giussani, Giorgia, González-Medina, Diego, Gosselin, Richard A, Gupta, Rahul, Hagan, Holly, Heuton, Kyle R, Husseini, Abdullatif, Huynh, Chantal, Iburg, Kim M, Islami, Farhad, Jarvis, Deborah L, Jiang, Guohong, Jonas, Jost B, Karema, Corine K, Khan, Ejaz A, Kim, Yunjin, Kinfu, Yohannes, Kinge, Jonas M, Defo, Barthelemy Kuate, Leung, Ricky, Logroscino, Giancarlo, Matzopoulos, Richard, Melaku, Yohannes A, Mitchell, Philip B, Montico, Marcella, Moturi, Wilkister N, Neupane, Sudan P, Ngalesoni, Frida N, Nisar, Muhammad I, Phillips, Michael R, Piel, Frédéric B, Poenaru, Dan, Prasad, Noela M, Qato, Dima M, Raju, Murugesan, Richardus, Jan Hendrik, Roberts, D Allen, Rojas-Rueda, David, Saeedi, Mohammad Y, Sahraian, Mohammad Ali, Scarborough, Peter, Schöttker, Ben, Shackelford, Katya A, Shaheen, Amira, Shiri, Rahman, Shishani, Kawkab, Sliwa, Karen, Stanaway, Jeffrey D, Stathopoulou, Vasiliki, Steiner, Caitlyn, Stovner, Lars J, Sunguya, Bruno F, Swaroop, Mamta, Tanner, Marcel, Ao, Braden J Te, Undurraga, Eduardo A, Wilkinson, James D, Williams, Thomas N, Xu, Gelin, Yonemoto, Naohiro, Yoon, Seok-Jun, Yu, Chuanhua, Vos, Theo
Published in The Lancet (British edition)

Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016

by Aboyans, Victor, Agrawal, Anurag, Aichour, Miloud Taki Eddine, Aichour, Ibtihel, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Allebeck, Peter, Alsharif, Ubai, Alvis-Guzman, Nelson, Anber, Nahla, Antonio, Carl Abelardo T, Asgedom, Solomon W, Avokpaho, Euripide Frinel G, Bacha, Umar, Barrero, Lope H, Beuran, Mircea, Bhatt, Samir, Cahuana-Hurtado, Lucero, Car, Josip, Casey, Daniel C, Chibueze, Chioma Ezinne, Criqui, Michael H, Dandona, Lalit, Defo, Barthelemy Kuate, Deiparine, Selina, Doku, David Teye, Farinha, Carla Sofia e Sa, Fraser, Maya, Gebremichael, Delelegn Yilma, Goldberg, Ellen M, Gupta, Vipin, Hankey, Graeme J, Hosgood, H Dean, Hostiuc, Sorin, Hoy, Damian G, Huynh, Chantal, Ileanu, Bogdan Vasile, Javanbakht, Mehdi, Kabir, Zubair, Kamal, Ritul, Karch, André, Karimkhani, Chante, Kawakami, Norito, Khader, Yousef Saleh, Kim, Daniel, Kimokoti, Ruth W, Lalloo, Ratilal, Lan, Qing, Lee, Paul H, Levi, Miriam, Li, Yongmei, Lorkowski, Stefan, Maddison, Emilie R, Martopullo, Ira, McGaughey, Madeline, Mensah, George A, Miller, Ted R, Mirarefin, Mojde, Mirrakhimov, Erkin M, Mishra, Shiva Raj, Molokhia, Mariam, Montañez, Julio C, Montico, Marcella, Morawska, Lidia, Nguyen, Minh, Okoro, Anselm, Opio, John Nelson, PA, Mahesh, Panda, Basant Kumar, Paudel, Deepak, Plass, Dietrich, Roshandel, Gholamreza, Saadat, Soheil, Sahathevan, Ramesh, Samy, Abdallah M, Santos, Itamar S, Santric Milicevic, Milena M, Schneider, Ione J C, Shaikh, Masood Ali, Shamsipour, Mansour, Shey, Muki, Shields, Chloe, Skiadaresi, Eirini, Sligar, Amber, Smith, Mari, Sorensen, Reed J D, Steinke, Sabine, Strub, Bryan, Sur, Patrick J, Talongwa, Roberto Tchio, Thrift, Amanda G, Troeger, Christopher, Tyrovolas, Stefanos, Updike, Rachel, Vasankari, Tommi, Weiss, Daniel J, Werdecker, Andrea, Xu, Gelin, Younis, Mustafa Z, Murray, Christopher J L
Published in The Lancet (British edition)

CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment

by Jin, Yan, Desta, Zeruesenay, Stearns, Vered, Ward, Bryan, Ho, Herbert, Lee, Kyung-Hoon, Skaar, Todd, Storniolo, Anna Maria, Li, Lang, Araba, Adjei, Blanchard, Rebecca, Nguyen, Anne, Ullmer, Lynda, Hayden, Jill, Lemler, Suzanne, Weinshilboum, Richard M., Rae, James M., Hayes, Daniel F., Flockhart, David A.
Published in JNCI : Journal of the National Cancer Institute

Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of...

by Abate, Kalkidan Hassen, Abd-Allah, Foad, Abera, Semaw Ferede, Abu-Raddad, Laith J, Adetokunboh, Olatunji, Afshin, Ashkan, Agrawal, Sutapa, Ahmadieh, Hamid, Aichour, Ibtihel, Ammar, Walid, Anwari, Palwasha, Azzopardi, Peter, Bannick, Marlena S, Bedi, Neeraj, Bell, Michelle L, Bennett, Derrick A, Betsu, Balem Demtsu, Bikbov, Boris, Boneya, Dube Jara, Butt, Zahid A, Cameron, Ewan, Cárdenas, Rosario, Castañeda-Orjuela, Carlos A, Castro, Ruben Estanislao, Chitheer, Abdulaal A, Cromwell, Elizabeth A, das Neves, José, Dubey, Manisha, Estep, Kara, Feigin, Valery L, Fernandes, João C, Filip, Irina, Friedman, Joseph, Gishu, Melkamu Dedefo, Giussani, Giorgia, Glenn, Scott D, Hareri, Habtamu Abera, Hendrie, Delia, John, Denny, Johnson, Catherine O, Karema, Corine Kakizi, Keiyoro, Peter Njenga, Koyanagi, Ai, Kyu, Hmwe H, Lazarus, Jeffrey Victor, Li, Yongmei, Lozano, Rafael, McGrath, John J, Mehndiratta, Man Mohan, Meier, Toni, Meretoja, Tuomo J, Mezgebe, Haftay Berhane, Millear, Anoushka, Misganaw, Awoke, Mohammed, Kedir Endris, Naheed, Aliya, Nong, Vuong Minh, Norheim, Ole F, Noubiap, Jean Jacques N, Oh, In-Hwan, Ortiz, Alberto, Panda-Jonas, Songhomitra, Papachristou, Christina, Pillay, Julian David, Pinho, Christine, Piradov, Michael A, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rao, Puja C, Reinig, Nikolas, Remuzzi, Giuseppe, Renzaho, Andre M N, Rios Blancas, Maria Jesus, Rivas, Jacqueline Castillo, Roshandel, Gholamreza, Sartorius, Benn, Schneider, Ione J C, Shahraz, Saeid, Shamsizadeh, Morteza, Shi, Peilin, Shiri, Rahman, Silberberg, Donald H, Silveira, Dayane Gabriele Alves, Singh, Jasvinder A, Sinha, Dhirendra Narain, Skiadaresi, Eirini, Smith, Alison, Smith, Mari, Sorensen, Reed J D, Steiner, Caitlyn, Sunguya, Bruno F, Szoeke, Cassandra E I, Torre, Anna, Vollset, Stein Emil, Weichenthal, Scott, Yan, Lijing L, Yaseri, Mehdi, Zavala-Arciniega, Luis, Zodpey, Sanjay
Published in The Lancet (British edition)

The Public Health Gains Had Cigarette Companies Chosen to Sell Very Low Nicotine Cigarettes

by Levy, David T, Cummings, K Michael, Heckman, Bryan W, Li, Yameng, Yuan, Zhe, Smith, Tracy T, Meza, Rafael
Published in Nicotine & tobacco research

Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness

by Bain, William, Li, Huihua, van der Geest, Rick, Moore, Sara R, Olonisakin, Tolani F, Ahn, Brian, Papke, Erin, Moghbeli, Kaveh, DeSensi, Rebecca, Rapport, Sarah, Saul, Melissa, Hulver, Mei, Xiong, Zeyu, Mallampalli, Rama K, Ray, Prabir, Morris, Alison, Ma, Lina, Doi, Yohei, Zhang, Yingze, Kitsios, Georgios D, Kulkarni, Hrishikesh S, McVerry, Bryan J, Ferreira, Viviana P, Nouraie, Mehdi, Lee, Janet S
Published in American journal of respiratory and critical care medicine

A Functional Epidermal Growth Factor (EGF) Polymorphism, EGF Serum Levels, and Esophageal Adenocarcinoma Risk and Outcome

by Lanuti, Michael, Liu, Geoffrey, Goodwin, Jonathan M, Zhai, Rihong, Fuchs, Bryan C, Asomaning, Kofi, Su, Li, Nishioka, Norman S, Tanabe, Kenneth K, Christiani, David C
Published in Clinical cancer research

Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer

by Fu, Siqing, Hennessy, Bryan T, Ng, Chaan S, Ju, Zhenlin, Coombes, Kevin R, Wolf, Judith K, Sood, Anil K, Levenback, Charles F, Coleman, Robert L, Kavanagh, John J, Gershenson, David M, Markman, Maurie, Dice, Kristine, Howard, Adrienne, Li, Jane, Li, Yang, Stemke-Hale, Katherine, Dyer, Mary, Atkinson, Edward, Jackson, Ed, Kundra, Vikas, Kurzrock, Razelle, Bast, Robert C, Mills, Gordon B
Published in Gynecologic oncology

Pre-B-Cell Colony-enhancing Factor as a Potential Novel Biomarker in Acute Lung Injury

by Ye, Shui Q, Simon, Brett A, Maloney, James P, Zambelli-Weiner, April, Gao, Li, Grant, Audrey, Easley, R. Blaine, McVerry, Bryan J, Tuder, Rubin M, Standiford, Theodore, Brower, Roy G, Barnes, Kathleen C, Garcia, Joe G. N
Published in American journal of respiratory and critical care medicine

Global mortality estimates for the 2009 Influenza Pandemic from the GLaMOR project: a modeling study

by Simonsen, Lone, Spreeuwenberg, Peter, Lustig, Roger, Taylor, Robert J, Fleming, Douglas M, Kroneman, Madelon, Van Kerkhove, Maria D, Mounts, Anthony W, Paget, W John
Published in PLoS medicine

Intraoperative Conversion From Partial to Radical Nephrectomy: Incidence, Predictive Factors, and Outcomes

by Petros, Firas G., Keskin, Sarp K., Yu, Kai-Jie, Li, Roger, Metcalfe, Michael J., Fellman, Bryan M., Chang, Courtney M., Gu, Cindy, Tamboli, Pheroze, Matin, Surena F., Karam, Jose A., Wood, Christopher G.
Published in Urology (Ridgewood, N.J.)

Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: results from a population-based study

by Tan, W C, Bourbeau, J, Hernandez, P, Chapman, K R, Cowie, R, FitzGerald, J M, Marciniuk, D D, Maltais, F, Buist, A S, O'Donnell, D E, Sin, D D, Aaron, S D
Published in Thorax

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

by Lange, Leslie A., Schmidt, Ellen M., Bizon, Chris, Jun, Goo, Auer, Paul, Li, Kuo-ping, Locke, Adam, Rivas, Manuel A., Feitosa, Mary F., Zhang, Qunyuan, Huffman, Jennifer E., Crosby, Jacy, Robinson, Jennifer G., Crosslin, David R., Rosenthal, Elisabeth A., Tsai, Michael, Rieder, Mark J., Fox, Ervin R., van Duijn, Cornelia M., Taylor, Herman A., Loos, Ruth J.F., Ballantyne, Christie M., Reiner, Alexander P., Cupples, L. Adrienne, Kang, Hyun Min, Lettre, Guillaume, Rader, Daniel J., Reilly, Muredach P., Stoletzki, Nina, Barr, R. Graham, Benjamin, Emelia J., Carr, Jeff, Dupuis, Josée, Ellis, Jaclyn, Fornage, Myriam, Goff, David, Grody, Wayne, Heard-Costa, Nancy L., Levy, Daniel, Li, Dalin, Loria, Cay, Mackey, Rachel, Quinlan, Aaron R., Rice, Kenneth, Sanders, Jill P., Tracy, Russell P., Tsai, Michael Y., Wassel, Chrstina L., Watson, Karol, Wilson, Gregory, Wilson, James G., Zakai, Neil A., Nalls, Michael, Bamshad, Michael J., Accurso, Frank, Beaty, Terri, Caplan, Daniel, Chidekel, Aaron, Christiani, David C., De Paula, Alicia, Gutierrez, Hector, Hassoun, Paul M., Hiatt, Peter, Hummer, Laura K., Kim, Yoonhee, Lin, Xihong, Louie, Tin L., Mathias, Rasika A., McNamara, John, McNamara, Sharon, Nielson, Dennis, Orenstein, David, O’Sullivan, Brian, Passero, Mary Ann, Perkett, Elizabeth, Spencer, Terry, Tabor, Holly K., Weiss, Robert, Wigley, Fred, Wise, Robert A., Wurfel, Mark M., Eichler, Evan E., Fu, Wenqing, Smith, Joshua D., Tennessen, Jacob A., Peters, Ulrike, Brzyski, Robert, Curb, J. David, Eaton, Charles B., Heiss, Gerardo, Johnson, Karen C., Lasser, Norman, Lin, Dan-Yu, Logsdon, Benjamin A., Manson, JoAnn E., Martin, Lisa, Stein, Evan, Applebaum-Bowden, Deborah, Paltoo, Dina N., Sturcke, Anne
Published in American journal of human genetics

Plasma 1,3-β-d-glucan levels predict adverse clinical outcomes in critical illness

by Kitsios, Georgios D, Kotok, Daniel, Yang, Haopu, Finkelman, Malcolm A, Zhang, Yonglong, Britton, Noel, Li, Xiaoyun, Levochkina, Marina S, Wagner, Amy K, Schaefer, Caitlin, Villandre, John J, Guo, Rui, Evankovich, John W, Bain, William, Shah, Faraaz, Zhang, Yingze, Methé, Barbara A, Benos, Panayiotis V, McVerry, Bryan J, Morris, Alison
Published in JCI insight