Progression analysis versus traditional methods to quantify slowing of disease progression in Alzheimer's disease

by Jönsson, Linus, Ivkovic, Milana, Atri, Alireza, Handels, Ron, Gustavsson, Anders, Hahn-Pedersen, Julie Hviid, León, Teresa, Lilja, Mathias, Gundgaard, Jens, Raket, Lars Lau
Published in Alzheimer's research & therapy

BH3 mimetics as anti-fibrotic therapy: Unleashing the mitochondrial pathway of apoptosis in myofibroblasts

by Kuehl, Tobias, Lagares, David
Published in Matrix biology

Exploring new uses for existing drugs: innovative mechanisms to fund independent clinical research

by Verbaanderd, Ciska, Rooman, Ilse, Huys, Isabelle
Published in Current controlled trials in cardiovascular medicine

Serum cytokine levels of COVID-19 patients after 7 days of treatment with Favipiravir or Kaletra

by Mortaz, Esmaeil, Bassir, Ali, Dalil Roofchayee, Neda, Dezfuli, Neda K., Jamaati, Hamidreza, Tabarsi, Payam, Moniri, Afshin, Rezaei, Mitra, Mehrian, Payam, Varahram, Mohammad, Marjani, Majid, Mumby, Sharon, Adcock, Ian M.
Published in International immunopharmacology

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c + dendritic cells

by Giuliani, Kurt T K, Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S, Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M, Healy, Helen, Kassianos, Andrew J
Published in Cell death & disease

pH-Responsive poly(itaconic acid-co-N-vinylpyrrolidone) hydrogels with reduced ionic strength loading solutions offer improved oral delivery potential for high isoelectric point-ex...

by Koetting, Michael C., Peppas, Nicholas A.
Published in International journal of pharmaceutics

Clinical Research on Alzheimer’s Disease: Progress and Perspectives

by Sun, Bin-Lu, Li, Wei-Wei, Zhu, Chi, Jin, Wang-Sheng, Zeng, Fan, Liu, Yu-Hui, Bu, Xian-Le, Zhu, Jie, Yao, Xiu-Qing, Wang, Yan-Jiang
Published in Neuroscience bulletin

Statistical controversies in clinical research: basket trials, umbrella trials, and other master protocols: a review and examples

by Renfro, L.A., Sargent, D.J.
Published in Annals of oncology

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

by Beautrait, Alexandre, Paradis, Justine S, Zimmerman, Brandon, Giubilaro, Jenna, Nikolajev, Ljiljana, Armando, Sylvain, Kobayashi, Hiroyuki, Yamani, Lama, Namkung, Yoon, Heydenreich, Franziska M, Khoury, Etienne, Audet, Martin, Roux, Philippe P, Veprintsev, Dmitry B, Laporte, Stéphane A, Bouvier, Michel
Published in Nature communications

Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis

by Stone, Julie A., McCrea, Jacqueline B., Witter, Rose, Zajic, Stefan, Stoch, S. Aubrey
Published in British journal of clinical pharmacology

Metabolomics in the study of retinal health and disease

by Laíns, Inês, Gantner, Mari, Murinello, Salome, Lasky-Su, Jessica A., Miller, Joan W., Friedlander, Martin, Husain, Deeba
Published in Progress in retinal and eye research

Direct Cytosolic Delivery of Proteins through Coengineering of Proteins and Polymeric Delivery Vehicles

by Lee, Yi-Wei, Luther, David C, Goswami, Ritabrita, Jeon, Taewon, Clark, Vincent, Elia, James, Gopalakrishnan, Sanjana, Rotello, Vincent M
Published in Journal of the American Chemical Society

Progress and challenges of immunotherapy in triple-negative breast cancer

by Zhu, Yinxing, Zhu, Xuedan, Tang, Cuiju, Guan, Xiaoxiang, Zhang, Wenwen
Published in Biochimica et biophysica acta. Reviews on cancer

Renal cell carcinoma therapy: Current and new drug candidates

by Pontes, Olívia, Oliveira-Pinto, Sofia, Baltazar, Fátima, Costa, Marta
Published in Drug discovery today

Combined Inhibition of SHP2 and MEK Is Effective in Models of NF1-Deficient Malignant Peripheral Nerve Sheath Tumors

by Wang, Jiawan, Pollard, Kai, Allen, Amy N, Tomar, Tushar, Pijnenburg, Dirk, Yao, Zhan, Rodriguez, Fausto J, Pratilas, Christine A
Published in Cancer research (Chicago, Ill.)

Recent advances in DDR (DNA damage response) inhibitors for cancer therapy

by Cheng, Binbin, Pan, Wei, Xing, Yi, Xiao, Yao, Chen, Jianjun, Xu, Zheng
Published in European journal of medicinal chemistry

Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma

by Larson, Rebecca C, Kann, Michael C, Graham, Charlotte, Mount, Christopher W, Castano, Ana P, Lee, Won-Ho, Bouffard, Amanda A, Takei, Hana N, Almazan, Antonio J, Scarfó, Irene, Berger, Trisha R, Schmidts, Andrea, Frigault, Matthew J, Gallagher, Kathleen M E, Maus, Marcela V
Published in Nature communications

Current status and future outlook for patient‐derived cancer models from a rare cancer research perspective

by Kondo, Tadashi
Published in Cancer science

Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration

by Ingraham, 4th, Charles H, Stalinska, Joanna, Carson, Sean C, Colley, Susan B, Rak, Monika, Lassak, Adam, Peruzzi, Francesca, Reiss, Krzysztof, Jursic, Branko S
Published in Scientific reports

Engineering cytokines for cancer immunotherapy: a systematic review

by Fu, Yong, Tang, Renhong, Zhao, Xiaofeng
Published in Frontiers in immunology