Critical Assessment of Targeted Protein Degradation as a Research Tool and Pharmacological Modality

by Kostic, Milka, Jones, Lyn H.
Published in Trends in pharmacological sciences (Regular ed.)

Effects of exercise on Irisin, BDNF and IL-6 serum levels in patients with progressive multiple sclerosis

by Briken, Sven, Rosenkranz, Sina Cathérine, Keminer, Oliver, Patra, Stefan, Ketels, Gesche, Heesen, Christoph, Hellweg, Rainer, Pless, Ole, Schulz, Karl-Heinz, Gold, Stefan M
Published in Journal of neuroimmunology

Oncology Meets Immunology: The Cancer-Immunity Cycle

by Chen, Daniel S., Mellman, Ira
Published in Immunity (Cambridge, Mass.)

Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

by Howes, Oliver D, McCutcheon, Rob, Agid, Ofer, de Bartolomeis, Andrea, van Beveren, Nico J.M, Birnbaum, Michael L, Bloomfield, Michael A.P, Bressan, Rodrigo A, Buchanan, Robert W, Carpenter, William T, Castle, David J, Citrome, Leslie, Daskalakis, Zafiris J, Davidson, Michael, Drake, Richard J, Dursun, Serdar, Ebdrup, Bjørn H, Elkis, Helio, Falkai, Peter, Fleischacker, W. Wolfgang, Gadelha, Ary, Gaughran, Fiona, Glenthøj, Birte Y, Graff-Guerrero, Ariel, Hallak, Jaime E.C, Honer, William G, Kennedy, James, Kinon, Bruce J, Lawrie, Stephen M, Lee, Jimmy, Leweke, F. Markus, MacCabe, James H, McNabb, Carolyn B, Meltzer, Herbert, Möller, Hans-Jürgen, Nakajima, Shinchiro, Pantelis, Christos, Reis Marques, Tiago, Remington, Gary, Rossell, Susan L, Russell, Bruce R, Siu, Cynthia O, Suzuki, Takefumi, Sommer, Iris E, Taylor, David, Thomas, Neil, Üçok, Alp, Umbricht, Daniel, Walters, James T.R, Kane, John, Correll, Christoph U
Published in The American journal of psychiatry

Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting

by Anttila, Vesa, Saraste, Antti, Knuuti, Juhani, Hedman, Marja, Jaakkola, Pekka, Laugwitz, Karl-Ludwig, Krane, Markus, Jeppsson, Anders, Sillanmäki, Saara, Rosenmeier, Jaya, Zingmark, Pernilla, Rudvik, Anna, Garkaviy, Pavlo, Watson, Christina, Pangalos, Menelas N., Chien, Kenneth R., Fritsche-Danielson, Regina, Collén, Anna, Gan, Li-Ming
Published in Molecular therapy

CRISPR-based therapeutics: current challenges and future applications

by Modell, Ashley E., Lim, Donghyun, Nguyen, Tuan M., Sreekanth, Vedagopuram, Choudhary, Amit
Published in Trends in pharmacological sciences (Regular ed.)

Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration

by Vest, Ryan T, Chou, Ching-Chieh, Zhang, Hui, Haney, Michael S, Li, Lulin, Laqtom, Nouf N, Chang, Betty, Shuken, Steven, Nguyen, Andy, Yerra, Lakshmi, Yang, Andrew C, Green, Carol, Tanga, Mary, Abu-Remaileh, Monther, Bassik, Michael C, Frydman, Judith, Luo, Jian, Wyss-Coray, Tony
Published in Proceedings of the National Academy of Sciences - PNAS

Cancer drug discovery by repurposing: teaching new tricks to old dogs

by Gupta, Subash C, Sung, Bokyung, Prasad, Sahdeo, Webb, Lauren J, Aggarwal, Bharat B
Published in Trends in pharmacological sciences (Regular ed.)

Enfortumab Vedotin Antibody-Drug Conjugate Targeting Nectin-4 Is a Highly Potent Therapeutic Agent in Multiple Preclinical Cancer Models

by Challita-Eid, Pia M, Satpayev, Daulet, Yang, Peng, An, Zili, Morrison, Karen, Shostak, Yuriy, Raitano, Arthur, Nadell, Rossana, Liu, Wendy, Lortie, Dawn Ratay, Capo, Linnette, Verlinsky, Alla, Leavitt, Monica, Malik, Faisal, Aviña, Hector, Guevara, Claudia I, Dinh, Nick, Karki, Sher, Anand, Banmeet S, Pereira, Daniel S, Joseph, Ingrid B J, Doñate, Fernando, Morrison, Kendall, Stover, David R
Published in Cancer research (Chicago, Ill.)

Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease

by Aillaud, Isabelle, Funke, Susanne Aileen
Published in Cellular and molecular neurobiology

Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa

by Margolin, Emmanuel, Burgers, Wendy A, Sturrock, Edward D, Mendelson, Marc, Chapman, Rosamund, Douglass, Nicola, Williamson, Anna-Lise, Rybicki, Edward P
Published in Nature reviews. Microbiology

Genetic alterations and their therapeutic implications in epithelial ovarian cancer

by Lapke, Nina, Chen, Chien-Hung, Chang, Ting-Chang, Chao, Angel, Lu, Yen-Jung, Lai, Chyong-Huey, Tan, Kien Thiam, Chen, Hua-Chien, Lu, Hsiao-Yun, Chen, Shu-Jen
Published in BMC cancer

Delivery of CD47-SIRPα checkpoint blocker by BCMA-directed UCAR-T cells enhances antitumor efficacy in multiple myeloma

by Lu, Qizhong, Yang, Donghui, Li, Hexian, Zhu, Zhixiong, Zhang, Zongliang, Chen, Yongdong, Yang, Nian, Li, Jia, Wang, Zeng, Niu, Ting, Tong, Aiping
Published in Cancer letters

Applications of Fluorine in Medicinal Chemistry

by Gillis, Eric P, Eastman, Kyle J, Hill, Matthew D, Donnelly, David J, Meanwell, Nicholas A
Published in Journal of medicinal chemistry

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

by Kowalski, Piotr S., Rudra, Arnab, Miao, Lei, Anderson, Daniel G.
Published in Molecular therapy

SARS-CoV-2 variants and ending the COVID-19 pandemic

by Fontanet, Arnaud, Autran, Brigitte, Lina, Bruno, Kieny, Marie Paule, Karim, Salim S Abdool, Sridhar, Devi
Published in The Lancet (British edition)

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy

by Quijano-Rubio, Alfredo, Bhuiyan, Aladdin M, Yang, Huilin, Leung, Isabel, Bello, Elisa, Ali, Lestat R, Zhangxu, Kevin, Perkins, Jilliane, Chun, Jung-Ho, Wang, Wentao, Lajoie, Marc J, Ravichandran, Rashmi, Kuo, Yun-Huai, Dougan, Stephanie K, Riddell, Stanley R, Spangler, Jamie B, Dougan, Michael, Silva, Daniel-Adriano, Baker, David
Published in Nature biotechnology

Hydrogen sulfide reduces pyroptosis and alleviates ischemia-reperfusion-induced acute kidney injury by inhibiting NLRP3 inflammasome

by Ni, Jindi, Jiang, Lijing, Shen, Guofeng, Xia, Zhuye, Zhang, Lu, Xu, Jing, Feng, Quanxia, Qu, Hongping, Xu, Fulin, Li, Xiang
Published in Life sciences (1973)

Unlocking the potential of agonist antibodies for treating cancer using antibody engineering

by Jhajj, Harkamal S., Lwo, Timon S., Yao, Emily L., Tessier, Peter M.
Published in Trends in molecular medicine

Machine learning–based integration of network features and chemical structure of compounds for SARS‐CoV‐2 drug effect analysis

by Späth, Julian, Wang, Rui‐Sheng, Humphrey, Maeve, Baumbach, Jan, Loscalzo, Joseph
Published in CPT: pharmacometrics and systems pharmacology