The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance

by Meads, Mark B, Hazlehurst, Lori A, Dalton, William S
Published in Clinical cancer research

Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma

by Zhao, Xiaohong, Lwin, Tint, Silva, Ariosto, Shah, Bijal, Tao, Jiangchuan, Fang, Bin, Zhang, Liang, Fu, Kai, Bi, Chengfeng, Li, Jiannong, Jiang, Huijuan, Meads, Mark B, Jacobson, Timothy, Silva, Maria, Distler, Allison, Darville, Lancia, Zhang, Ling, Han, Ying, Rebatchouk, Dmitri, Di Liberto, Maurizio, Moscinski, Lynn C, Koomen, John M, Dalton, William S, Shain, Kenneth H, Wang, Michael, Sotomayor, Eduardo, Tao, Jianguo
Published in Nature communications

A pharmacodynamic model of clinical synergy in multiple myeloma

by Sudalagunta, Praneeth, Silva, Maria C., Canevarolo, Rafael R., Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert, Gillies, Robert, Baz, Rachid, Meads, Mark B., Shain, Kenneth H., Silva, Ariosto S.
Published in EBioMedicine

An Ex Vivo Platform for the Prediction of Clinical Response in Multiple Myeloma

by Silva, Ariosto, Silva, Maria C, Sudalagunta, Praneeth, Distler, Allison, Jacobson, Timothy, Collins, Aunshka, Nguyen, Tuan, Song, Jinming, Chen, Dung-Tsa, Chen, Lu, Cubitt, Christopher, Baz, Rachid, Perez, Lia, Rebatchouk, Dmitri, Dalton, William, Greene, James, Gatenby, Robert, Gillies, Robert, Sontag, Eduardo, Meads, Mark B, Shain, Kenneth H
Published in Cancer research (Chicago, Ill.)

CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation

by Jiang, Qibing, Sudalagunta, Praneeth, Silva, Maria C, Canevarolo, Rafael R, Zhao, Xiaohong, Ahmed, Khandakar Tanvir, Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert A, Gillies, Robert J, Baz, Rachid, Meads, Mark B, Shain, Kenneth H, Silva, Ariosto S, Zhang, Wei
Published in Bioinformatics

Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

by Zhao, Xiaohong, Wang, Michelle Y., Jiang, Huijuan, Lwin, Tint, Park, Paul M., Gao, Jing, Meads, Mark B., Ren, Yuan, Li, Tao, Sun, Jiao, Fahmi, Naima Ahmed, Singh, Satishkumar, Sehgal, Lalit, Wang, Xuefeng, Silva, Ariosto S., Sotomayor, Eduardo M., Shain, Kenneth H., Cleveland, John L., Wang, Michael, Zhang, Wei, Qi, Jun, Shah, Bijal D., Tao, Jianguo
Published in Cell reports (Cambridge)

A novel TNF receptor-associated factor 6 binding domain mediates NF-kappa B signaling by the common cytokine receptor beta subunit

by Meads, Mark B, Li, Zhi-Wei, Dalton, William S
Published in The Journal of immunology (1950)

Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechani...

by Meads, Mark B, Medveczky, Peter G
Published in The Journal of biological chemistry

IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB– and caspase-8–dependent mechanisms

by Zhou, Liang, Zhang, Yu, Meads, Mark B., Dai, Yun, Ning, Yanxia, Hu, Xiaoyan, Li, Lin, Sharma, Kanika, Nkwocha, Jewel, Parker, Rebecca, Bui, Danny, McCarter, Jacquelyn, Kramer, Lora, Purcell, Cullen, Sudalagunta, Praneeth R., Canevarolo, Rafael R., Coelho Siqueira Silva, Maria D., De Avila, Gabriel, Alugubelli, Raghunandan Reddy, Silva, Ariosto S., Kmeiciak, Maciej, Ferreira-Gonzalez, Andrea, Shain, Kenneth H., Grant, Steven
Published in Blood advances

Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma

by Mostofa, Agm, Distler, Allison, Meads, Mark B, Sahakian, Eva, Powers, John J, Achille, Alexandra, Noyes, David, Wright, Gabriela, Fang, Bin, Izumi, Victoria, Koomen, John, Rampakrishnan, Rupal, Nguyen, Tuan P, De Avila, Gabriel, Silva, Ariosto S, Sudalagunta, Praneeth, Canevarolo, Rafael Renatino, Siqueira Silva, Maria D Coelho, Alugubelli, Raghunandan Reddy, Dai, Hongyue A, Kulkarni, Amit, Dalton, William S, Hampton, Oliver A, Welsh, Eric A, Teer, Jamie K, Tungesvik, Alexandre, Wright, Kenneth L, Pinilla-Ibarz, Javier, Sotomayor, Eduardo M, Shain, Kenneth H, Brayer, Jason
Published in JCI insight

Static adhesion of cancer cells to glass surfaces coated with glycosaminoglycans

by Peramo, Antonio, Meads, Mark B., Dalton, William S., Matthews, W. Garrett
Published in Colloids and surfaces, B, Biointerfaces

Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation

by Shain, Kenneth H, Yarde, Danielle N, Meads, Mark B, Huang, Mei, Jove, Richard, Hazlehurst, Lori A, Dalton, William S
Published in Cancer research (Chicago, Ill.)

Convergent genetic and expression data implicate immunity in Alzheimer's disease

by Jones, Lesley, Wang, Li-San, Choi, Seung-Hoan, Vedernikov, Alexey, Escott-Price, Valentina, Richards, Alexander, Naj, Adam C., Sims, Rebecca, Gerrish, Amy, Jun, Gyungah, Beecham, Gary W., Grenier-Boley, Benjamin, Smith, Albert V., Chouraki, Vincent, Thomas, Charlene, Zelenika, Diana, Vardarajan, Badri N., Kamatani, Yoichiro, Bihoreau, Marie-Thérèse, Reitz, Christiane, Pasquier, Florence, Hanon, Olivier, Buxbaum, Joseph D., Campion, Dominique, Crane, Paul K., Gudnason, Vilmundur, Cruchaga, Carlos, Craig, David, Berr, Claudine, Lopez, Oscar L., De Jager, Philip L., Deramecourt, Vincent, Evans, Denis, Tárraga, Lluís, Sleegers, Kristel, Gill, Michael, Emilsson, Valur, Keller, Lina, Barberger-Gateau, Pascale, McGuinness, Bernadette, Larson, Eric B., Myers, Amanda J., Dufouil, Carole, Todd, Stephen, Love, Seth, Kehoe, Pat, Rogaeva, Ekaterina, Gallacher, John, Tsuang, Debby W., Yu, Lei, Sorbi, Sandro, Fox, Nick, Hardy, John, Deniz Naranjo, Maria Candida, Clarke, Robert, Mancuso, Michelangelo, Mecocci, Patrizia, del Zompo, Maria, Maier, Wolfgang, Pilotto, Alberto, Bullido, Maria, Caffarra, Paolo, Gilbert, John R., Mayhaus, Manuel, Lannfelt, Lars, Pichler, Sabrina, Ingelsson, Martin, Beekly, Duane, Valladares, Otto, Coto, Eliecer, Hamilton-Nelson, Kara L., Owen, Michael J., Faber, Kelley M., O'Donovan, Michael C., Soininen, Hilkka, Mead, Simon, de Bruijn, Renee F.A.G., Rotter, Jerome I., Brice, Alexis, Morgan, Kevin, Foroud, Tatiana M., Hannequin, Didier, Powell, John F., Nalls, Michael A., Ritchie, Karen, Riemenschneider, Matthias, Boada, Mercè, Hiltunen, Mikko, Pastor, Pau, Mayeux, Richard, Graff, Caroline, Psaty, Bruce M., Haines, Jonathan L., Lathrop, Mark, Pericak-Vance, Margaret A., Launer, Lenore J., Farrer, Lindsay A., van Duijn, Cornelia M., Williams, Julie, Holmans, Peter A.
Published in Alzheimer's & dementia

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis

by Mehrotra, Rajnish, Stanaway, Ian B., Jarvik, Gail P., Lambie, Mark, Morelle, Johann, Perl, Jeffrey, Himmelfarb, Jonathan, Heimburger, Olof, Johnson, David W., Imam, Talha H., Robinson, Bruce, Stenvinkel, Peter, Devuyst, Olivier, Davies, Simon J., Pisoni, Ronald, Robinson, Bruce, Johnson, David, Cho, Yeoungjee, Wong, Muh Geot, Mather, Amanda, Cooper, Bruce, Devuyst, Olivier, Morelle, Johann, Goffin, Eric, Bammens, Bert, Bovy, Philippe, Margetts, Peter, Perl, Jeffrey, Taylor, Paul, Jain, Arsh, Jassal, Vanita, Stenvinkel, Peter, Heimburger, Olof, Kuan, Ying, Harron, Camille, Dasgupta, Indranil, Stoves, John, Akbani, Habib, Abeygunasekara, Sumith, Sharples, Edward, Mead, Paul, Hayat, Amer, Morgan, Neal, Cramp, Hilary, Robertson, Susan, Fielding, Richard, Brown, Edwina, Collinson, Helen, Ande, Pravene, Doulton, Tim, MacDougall, Iain, Cairns, Hugh, Vilar, Enric, Vardhan, Anand, Chess, James, Sandhu, Kanwaljit, Wilkie, Martin, McHaffie, Gavin, Lewis, Robert, Kamesh, Lavanya, Buck, Kate, Peel, Robert, Taylor, Jo, Johnston, Paul, Leung, Janson, Bingham, Coralie, Anijeet, Hameed, Ranakrishna, Satish, Nair, Sunita, Iggo, Neil, Lewis, David, Udayaraj, Uday, Dawson, Susan, Woordrow, Graham, Chandrasekar, Thangavelu, Hamer, Rizwan, Davies, Simon, Donovan, Kieron, Jones, Colin, Ynares, Christina, Dukes, Carl, Imam, Talha H., Corapi, Kristin, Nigwekar, Sagar, Khawar, Osman, Weiner, Daniel, Lau, Wei Ling, Harley, Kevin, Ghaffari, Arshia, Saxena, Ramesh, Abraham, Josephine, Mehrotra, Rajnish, Himmelfarb, Jonathan, Cavanaugh, Kerri L., Golper, Thomas A., Burkart, John M., Pirkle, James L., Miller, Brent, Jang, Judy, Turner, Jeffrey
Published in Kidney international

Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe)

by Sobrin, Lucia, Green, Todd, Sim, Xueling, Jensen, Richard A, Tai, E Shyong, Tay, Wan Ting, Wang, Jie Jin, Mitchell, Paul, Sandholm, Niina, Liu, Yiyuan, Hietala, Kustaa, Iyengar, Sudha K, Brooks, Matthew, Buraczynska, Monika, Van Zuydam, Natalie, Smith, Albert V, Gudnason, Vilmundur, Doney, Alex S F, Morris, Andrew D, Leese, Graham P, Palmer, Colin N A, Swaroop, Anand, Taylor, Jr, Herman A, Wilson, James G, Penman, Alan, Chen, Ching J, Groop, Per-Henrik, Saw, Seang-Mei, Aung, Tin, Klein, Barbara E, Rotter, Jerome I, Siscovick, David S, Cotch, Mary Frances, Klein, Ronald, Daly, Mark J, Wong, Tien Y
Published in Investigative ophthalmology & visual science

Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

by Ge, Yi-Jun, Zhang, Ya-Ru, Huang, Yu-Yuan, Dong, Qiang, Tan, Lan, Ferrari, Raffaele, Ramasamy, Adaikalavan, Kwok, John B.J., Dobson-Stone, Carol, Schofield, Peter R., Halliday, Glenda M., Piguet, Olivier, Bartley, Lauren, Thompson, Elizabeth, Haan, Eric, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Cruchaga, Carlos, Benussi, Luisa, Galimberti, Daniela, Fenoglio, Chiara, Scarpini, Elio, Lleó, Alberto, Nilsson, Karin, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Morris, Christopher M., Attems, Johannes, Thomas, Alan J., Pietrini, P., Huey, Edward D., Tierney, Michael C., Pastor, Pau, Razquin, Cristina, Ortega-Cubero, Sara, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Kurz, Alexander, Rainero, Innocenzo, Rogaeva, Ekaterina, Rossi, Giacomina, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Mead, Simon, Danek, Adrian, Van Langenhove, Tim, Cappa, Stefano F., Hannequin, Didier, Vercelletto, Martine, Brice, Alexis, Nacmias, Benedetta, Bagnoli, Silvia, Nielsen, Jørgen E., Ibach, Bernd, Gasparoni, Gilles, Gu, Wei, Warren, Jason D., Spillantini, Maria Grazia, Morris, Huw R., Snowden, Julie S., Rollinson, Sara, Richardson, Anna, Gerhard, Alexander, Bruni, Amalia C., Maletta, Raffaele, Cupidi, Chiara, Gallo, Maura, Smirne, Nicoletta, Rademakers, Rosa, Baker, Matt, Dickson, Dennis W., Petersen, Ronald C., Knopman, David, Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Miller, Bruce L., Karydas, Anna M., van Swieten, John C., Seelaar, Harro, Pijnenburg, Yolande A.L., Logroscino, Giancarlo, Capozzo, Rosa, Puca, Annibale A., Franceschi, Massimo, Postiglione, Alfredo, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Rollin, Adeline, Lebert, Florence, Kapogiannis, Dimitrios, Ferrucci, Luigi, Hardy, John
Published in Biological psychiatry (1969)

ROR1 and ROR2 expression in pancreatic cancer

by Liu, Dongli, Sharbeen, George, Phillips, Phoebe, Ford, Caroline E
Published in BMC cancer

Further Validation and Responsiveness Assessment of the Herpes Outbreak Impact Questionnaire and Herpes Symptom Checklist

by Meads, David M., MSc, McKenna, Stephen P., PhD, Bonney, Mary-Ann, MAppSci, Bloch, Mark T., MB, BS, MMed
Published in Value in health

HOW WILL DIAGNOSIS-RELATED GROUPS AFFECT EPIDEMIOLOGIC RESEARCH?

by COHEN, BRUCE B., POKRAS, ROBERT, MEADS, M. SUE, KRUSHA, WILLIAM MARK
Published in American journal of epidemiology