The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories

by Tremblay, Karine, Rousseau, Simon, Zawati, Ma'n H, Auld, Daniel, Chassé, Michaël, Coderre, Daniel, Falcone, Emilia Liana, Gauthier, Nicolas, Grandvaux, Nathalie, Gros-Louis, François, Jabet, Carole, Joly, Yann, Kaufmann, Daniel E, Laprise, Catherine, Larochelle, Catherine, Maltais, François, Mes-Masson, Anne-Marie, Montpetit, Alexandre, Piché, Alain, Richards, J Brent, Tse, Sze Man, Turgeon, Alexis F, Turecki, Gustavo, Vinh, Donald C, Wang, Han Ting, Mooser, Vincent
Published in PloS one

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

by Yuan, Xin, Waterworth, Dawn, Perry, John R.B., Lim, Noha, Song, Kijoung, Chambers, John C., Zhang, Weihua, Vollenweider, Peter, Stirnadel, Heide, Johnson, Toby, Bergmann, Sven, Beckmann, Noam D., Li, Yun, Ferrucci, Luigi, Melzer, David, Hernandez, Dena, Singleton, Andrew, Scott, James, Elliott, Paul, Waeber, Gerard, Cardon, Lon, Frayling, Timothy M., Kooner, Jaspal S., Mooser, Vincent
Published in American journal of human genetics

Performance of genotype imputation for rare variants identified in exons and flanking regions of genes

by Li, Li, Li, Yun, Browning, Sharon R, Browning, Brian L, Slater, Andrew J, Kong, Xiangyang, Aponte, Jennifer L, Mooser, Vincent E, Chissoe, Stephanie L, Whittaker, John C, Nelson, Matthew R, Ehm, Margaret Gelder
Published in PloS one

A genome-wide association study of neuroticism in a population-based sample

by Calboli, Federico C F, Tozzi, Federica, Galwey, Nicholas W, Antoniades, Athos, Mooser, Vincent, Preisig, Martin, Vollenweider, Peter, Waterworth, Dawn, Waeber, Gerard, Johnson, Michael R, Muglia, Pierandrea, Balding, David J
Published in PloS one

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

by Jang, Yangsoo, Waterworth, Dawn, Lee, Jong-Eun, Song, Kijoung, Kim, Sujin, Kim, Hyo-Soo, Park, Kyung Woo, Cho, Hyun-Jai, Oh, Il-Young, Park, Jeong Euy, Lee, Bok-Soo, Ku, Hyo Jeong, Shin, Dong-Jik, Lee, Jong Ho, Jee, Sun Ha, Han, Bok-Ghee, Jang, Hye-Yoon, Cho, Eun-Young, Vallance, Patrick, Whittaker, John, Cardon, Lon, Mooser, Vincent
Published in PloS one

A Genomewide Scan for Early-Onset Coronary Artery Disease in 438 Families: The GENECARD Study

by Hauser, Elizabeth R., Crossman, David C., Granger, Christopher B., Haines, Jonathan L., Jones, Christopher J.H., Mooser, Vincent, McAdam, Brendan, Winkelmann, Bernhard R., Wiseman, Alan H., Muhlestein, J. Brent, Bartel, Alan G., Dennis, Charles A., Dowdy, Elaine, Estabrooks, Susan, Eggleston, Karen, Francis, Sheila, Roche, Kath, Clevenger, Paula W., Huang, Liling, Pedersen, Bonnie, Shah, Svati, Schmidt, Silke, Haynes, Carol, West, Sandra, Asper, Donny, Booze, Michael, Sharma, Sanjay, Sundseth, Scott, Middleton, Lefkos, Roses, Allen D., Hauser, Michael A., Vance, Jeffery M., Pericak-Vance, Margaret A., Kraus, William E.
Published in American journal of human genetics

Genome-wide association study identifies two loci strongly affecting transferrin glycosylation

by KUTALIK, Zoltán, BENYAMIN, Beben, VOLLENWEIDER, Peter, MARQUES-VIDAL, Pedro, WHITFIELD, John B, BERGMANN, Sven, MOOSER, Vincent, WAEBER, Gérard, MONTGOMERY, Grant W, MARTIN, Nicholas G, MADDEN, Pamela A. F, HEATH, Andrew C, BECKMANN, Jacques S
Published in Human molecular genetics

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

by Valsesia, Armand, Stevenson, Brian J, Waterworth, Dawn, Mooser, Vincent, Vollenweider, Peter, Waeber, Gérard, Jongeneel, C Victor, Beckmann, Jacques S, Kutalik, Zoltán, Bergmann, Sven
Published in BMC genomics

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

by Teumer, Alexander, Li, Man, Garnaas, Maija, Taliun, Daniel, Yang, Qiong, Ko, Yi-An, Isaacs, Aaron, d'Adamo, Pio, Dieffenbach, Aida Karina, Zonderman, Alan B, Nolte, Ilja M, Smith, Albert V, Uitterlinden, Andre G, Johansson, Åsa, Kollerits, Barbara, Freedman, Barry I, Ponte, Belen, Hayward, Caroline, Helmer, Catherine, van Duijn, Cornelia M, Ruggiero, Daniela, Toniolo, Daniela, Czamara, Darina, Siscovick, David S, Gieger, Christian, Rochtchina, Elena, Holliday, Elizabeth G, Salvi, Erika, Bottinger, Erwin P, Murgia, Federico, Rivadeneira, Fernando, Ernst, Florian, Kronenberg, Florian, Homuth, Georg, Coassin, Stefan, Thun, Gian-Andri, Malerba, Giovanni, Montgomery, Grant W, Eiriksdottir, Gudny, Jacobs, Gunnar, Li, Guo, Schmidt, Helena, Lin, Honghuang, Ford, Ian, Prokopenko, Inga, Kolcic, Ivana, Stafford, Jeanette M, Gaspoz, Jean-Michel, Smith, Jennifer A, Hirschhorn, Joel N, Whitfield, John B, Coresh, Josef, Keene, Keith L, Yengo, Loic, Ferrucci, Luigi, Rose, Lynda M, Struchalin, Maksim, Kleber, Marcus E, Cavalieri, Margherita, Haun, Margot, Ciullo, Marina, Woodward, Mark, Cocca, Massimiliano, Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Stumvoll, Michael, Kähönen, Mika, Bouatia-Naji, Nabila, Martin, Nicholas G, Hastie, Nick, Probst-Hensch, Nicole, Devuyst, Olivier, Raitakari, Olli, Gasparini, Paolo, Kovacs, Peter, Wild, Philipp S, Froguel, Philippe, Biffar, Reiner, Schmidt, Reinhold, Scott, Rodney J, Katz, Ronit, Hwang, Shih-Jen, Enroth, Stefan, Turner, Stephen T, Zeller, Tanja, Nikopensius, Tiit, Esko, Tonu, Aalto, Ville, Igl, Wilmar, Lieb, Wolfgang, Liu, Yongmei, Snieder, Harold, Susztak, Katalin, Hamet, Pavel, Goessling, Wolfram, Chasman, Daniel I, Köttgen, Anna, Kao, W H Linda, Fox, Caroline S
Published in Nature communications

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

by Munroe, Patricia B, Smith, Albert V, Verwoert, Germaine C, Amin, Najaf, Teumer, Alexander, Zhao, Jing Hua, Parsa, Afshin, Dehghan, Abbas, Peden, John F, Rudan, Igor, Chambers, John C, Fox, Ervin R, Alexander, Myriam, Tabara, Yasuharu, Seielstad, Mark, Kuznetsova, Tatiana, Ludwig, Barbara, Tomaszewski, Maciej, O'Connell, Jeffrey R, Kardia, Sharon L, Hingorani, Aroon D, Lawlor, Debbie A, Lawrence, Robert W, Clarke, Robert, Ongen, Halit, Li, Yali, Adair, Linda S, Lee, Nanette R, Bolton, Judith A Hoffman, Chaturvedi, Nish, Islam, Muhammad, Kulkarni, Smita R, Groop, Leif, Voight, Benjamin F, Guarrera, Simonetta, Plump, Andrew, Barroso, Inês, Vartiainen, Erkki, Burton, Paul R, Dong, Yanbin, Wang, Xiaoling, Lohman, Kurt K, Smith, Nicholas L, Kinra, Sanjay, Prabhakaran, Dorairaj, Forrester, Terrence, Hilton, Gina, McKenzie, Colin A, Kita, Yoshikuni, Wichmann, H-Erich, Zhang, Weihua, Hedblad, Bo, Nilsson, Peter, Wong, Andrew, Raffel, Leslie J, Yao, Jie, Schwartz, Stephen M, Ikram, M Arfan, Rasheed, Asif, Watkins, Hugh, Bakker, Stephan J L, van Gilst, Wiek H, Janipalli, Charles S, Rivadeneira, Fernando, Ala-Korpela, Mika, Soininen, Pasi, Völzke, Henry, Lathrop, Mark, Zelenika, Diana, Deloukas, Panos, Mangino, Massimo, Zhai, Guangju, Nalls, Michael A, Terzic, Janos, Kumar, M V Kranthi, Charchar, Fadi J, Schwarz, Peter E H, Guo, Xiuqing, Bots, Michiel L, Samani, Nilesh J, Palmer, Lyle J, Casas, Juan P, Vineis, Paolo, Raitakari, Olli, Wong, Tien Y, Tai, E Shyong, Cooper, Richard S, Rao, Dabeeru C, Harris, Tamara B, Morris, Richard W, Kivimaki, Mika, Coresh, Josef, Navis, Gerjan, Han, Bok-Ghee, Melander, Olle, Gyllensten, Ulf B, Rettig, Rainer, Uda, Manuela, Psaty, Bruce M, Abecasis, Gonçalo R
Published in Nature (London)

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

by JACQUEMONT, Sébastien, REYMOND, Alexandre, THORLEIFSSON, Gudmar, BELFIORE, Marco, BOUQUILLON, Sonia, CAMPION, Dominique, DE LEEUW, Nicole, DE VRIES, Bert B. A, ESKO, Tõnu, FERNANDEZ, Bridget A, FERNANDEZ-ARANDA, Fernando, FERNANDEZ-REAL, José Manuel, ZUFFEREY, Flore, GRATACOS, Mònica, GUILMATRE, Audrey, HOYER, Juliane, JARVELIN, Marjo-Riitta, FRANK KOOY, R, KURG, Ants, LE CAIGNEC, Cédric, MÄNNIK, Katrin, PLATT, Orah S, SANLAVILLE, Damien, HAREWOOD, Louise, VAN HAELST, Mieke M, VILLATORO GOMEZ, Sergi, WALHA, Faida, WU, Bai-Lin, YU, Yongguo, ABOURA, Azzedine, ADDOR, Marie-Claude, ALEMBIK, Yves, ANTONARAKIS, Stylianos E, ARVEILER, Benoît, WALTERS, Robin G, BARTH, Magalie, BEDNAREK, Nathalie, BENA, Frédérique, BERGMANN, Sven, BERI, Mylène, BERNARDINI, Laura, BLAUMEISER, Bettina, BONNEAU, Dominique, BOTTANI, Armand, BOUTE, Odile, KUTALIK, Zoltán, BRUNNER, Han G, CAILLEY, Dorothee, CALLIER, Patrick, CHIESA, Jean, CHRAST, Jacqueline, COIN, Lachlan, COUTTON, Charles, CUISSET, Jean-Marie, CUVELLIER, Jean-Christophe, DAVID, Albert, MARTINET, Danielle, YIPING SHEN, VALSESIA, Armand, BECKMANN, Noam D
Published in Nature (London)

Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome: the dal-GenE trial

by Tardif, Jean Claude, Pfeffer, Marc A, Kouz, Simon, Koenig, Wolfgang, Maggioni, Aldo P, McMurray, John J V, Mooser, Vincent, Waters, David D, Grégoire, Jean C, L’Allier, Philippe L, Wouter Jukema, J, White, Harvey D., Heinonen, Therese, Black, Donald M, Laghrissi-Thode, Fouzia, Levesque, Sylvie, Guertin, Marie Claude, Dubé, Marie Pierre
Published in European heart journal

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women

by Fox, Caroline S, Liu, Yongmei, White, Charles C, Feitosa, Mary, Smith, Albert V, Heard-Costa, Nancy, Lohman, Kurt, Johnson, Andrew D, Foster, Meredith C, Greenawalt, Danielle M, Griffin, Paula, Ding, Jinghong, Newman, Anne B, Tylavsky, Fran, Miljkovic, Iva, Kritchevsky, Stephen B, Launer, Lenore, Garcia, Melissa, Eiriksdottir, Gudny, Carr, J Jeffrey, Gudnason, Vilmunder, Harris, Tamara B, Cupples, L Adrienne, Borecki, Ingrid B
Published in PLoS genetics

A meta-analysis of gene expression signatures of blood pressure and hypertension

by Huan, Tianxiao, Esko, Tõnu, Peters, Marjolein J, Pilling, Luke C, Schramm, Katharina, Schurmann, Claudia, Chen, Brian H, Liu, Chunyu, Joehanes, Roby, Johnson, Andrew D, Yao, Chen, Ying, Sai-Xia, Courchesne, Paul, Milani, Lili, Raghavachari, Nalini, Wang, Richard, Liu, Poching, Reinmaa, Eva, Dehghan, Abbas, Hofman, Albert, Uitterlinden, André G, Hernandez, Dena G, Bandinelli, Stefania, Singleton, Andrew, Melzer, David, Metspalu, Andres, Carstensen, Maren, Grallert, Harald, Herder, Christian, Meitinger, Thomas, Peters, Annette, Roden, Michael, Waldenberger, Melanie, Dörr, Marcus, Felix, Stephan B, Zeller, Tanja, Vasan, Ramachandran, O'Donnell, Christopher J, Munson, Peter J, Yang, Xia, Prokisch, Holger, Völker, Uwe, van Meurs, Joyce B J, Ferrucci, Luigi, Levy, Daniel
Published in PLoS genetics

Large-scale gene-centric analysis identifies novel variants for coronary artery disease

by Butterworth, AS, Farrall, M, Hardwick, RJ, Saleheen, D, Peden, JF, Soranzo, N, Chambers, JC, Sivapalaratnam, S, Kleber, ME, Klopp, N, Erdmann, J, Assimes, TL, Ball, SG, Balmforth, AJ, Barnes, TA, Basart, H, Baumert, J, Bezzina, CR, Boerwinkle, E, Boehm, BO, Brocheton, J, Bugert, P, Cambien, F, Clarke, R, Codd, V, Collins, R, Couper, D, Cupples, LA, de Jong, JS, Diemert, P, Ejebe, K, Elbers, CC, Elliott, P, Fornage, M, Franzosi, MG, Frossard, P, Garner, S, Goel, A, Goodall, AH, Hengstenberg, C, Hunt, SE, Kastelein, JJP, Klungel, OH, Kluter, H, Koch, K, Konig, IR, Kooner, AS, Laaksonen, R, Lathrop, M, Li, MY, Liu, K, McPherson, R, Musameh, MD, Musani, S, Nelson, CP, O'Donnell, CJ, Ongen, H, Papanicolaou, G, Peters, A, Peters, BJM, Potter, S, Psaty, BM, Qu, LM, Rader, DJ, Rasheed, A, Rice, C, Scott, J, Seedorf, U, Sehmi, JS, Sotoodehnia, N, Stark, K, Stephens, J, van der Schoot, CE, van der Schouw, YT, Tomaszewski, M, van der Harst, P, Vasan, RS, Wilde, AAM, Willenborg, C, Winkelmann, BR, Zaidi, M, Zhang, WH, Ziegler, A, de Bakker, PIW, Koenig, W, Marz, W, Trip, MD, Reilly, MP, Kathiresan, S, Schunkert, H, Hamsten, A, Hall, AS, Kooner, JS, Thompson, SG, Thompson, JR, Deloukas, P, Ouwehand, WH, Watkins, H, Danesh, J, Samani, NJ
Published in PLoS genetics

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

by Heid, Iris M, Qi, Lu, Speliotes, Elizabeth K, Thorleifsson, Gudmar, Willer, Cristen J, Herrera, Blanca M, Jackson, Anne U, Lim, Noha, Scheet, Paul, Amin, Najaf, Chambers, John C, Drong, Alexander, Luan, Jian'an, Rivadeneira, Fernando, Sanna, Serena, Timpson, Nicholas J, Zhao, Jing Hua, Bergman, Richard N, Bonnycastle, Lori L, Bumpstead, Suzannah J, Chanock, Stephen J, Chines, Peter, Coin, Lachlan, Crawford, Gabriel, Doering, Angela, Dominiczak, Anna, Ebrahim, Shah, Ferrucci, Luigi, Fischer, Guido, Grallert, Harald, Groves, Christopher J, Grundy, Scott, Hadley, David, Hamsten, Anders, Havulinna, Aki S, Hofman, Albert, Holloway, John W, Illig, Thomas, Isomaa, Bo, Jacobs, Leonie C, Jameson, Karen, Jousilahti, Pekka, Karpe, Fredrik, Kuusisto, Johanna, Laitinen, Jaana, Lawlor, Debbie A, Mangino, Massimo, McArdle, Wendy L, Morris, Andrew P, Munroe, Patricia, Narisu, Narisu, Nordström, Anna, Nordström, Peter, Palmer, Colin N A, Peden, John F, Salomaa, Veikko, Sandhu, Manjinder S, Scott, Laura J, Scuteri, Angelo, Silander, Kaisa, Song, Kijoung, Yuan, Xin, Swift, Amy J, Tuomi, Tiinamaija, Waeber, Gerard, Wallace, Chris, Walters, G Bragi, Weedon, Michael N, Witteman, Jacqueline C M, Zhang, Weihua, Collins, Francis S, Davey Smith, George, Hattersley, Andrew T, Hu, Frank B, Jarvelin, Marjo-Riitta, Kooner, Jaspal S, Laakso, Markku, Lakatta, Edward, Mooser, Vincent, Morris, Andrew D, Samani, Nilesh J, Strachan, David P, Tanaka, Toshiko, Tuomilehto, Jaakko, van Duijn, Cornelia M, Wareham, Nicholas J, Hugh Watkins, Boehnke, Michael, Deloukas, Panos, Groop, Leif, Hunter, David J, Thorsteinsdottir, Unnur, Schlessinger, David, Wichmann, H-Erich, Frayling, Timothy M, Hirschhorn, Joel N, Loos, Ruth J F, Stefansson, Kari, Mohlke, Karen L, McCarthy, Mark I
Published in PLoS genetics

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

by Cousminer, Diana L, Stergiakouli, Evangelia, Berry, Diane J, Ang, Wei, Groen-Blokhuis, Maria M, Körner, Antje, Siitonen, Niina, Ntalla, Ioanna, Marinelli, Marcella, Perry, John R B, Kettunen, Johannes, Jansen, Rick, Surakka, Ida, Timpson, Nicholas J, Ring, Susan, Mcmahon, George, Power, Chris, Wang, Carol, Kähönen, Mika, Viikari, Jorma, Lehtimäki, Terho, Middeldorp, Christel M, Hulshoff Pol, Hilleke E, Neef, Madlen, Weise, Sebastian, Pahkala, Katja, Niinikoski, Harri, Zeggini, Eleftheria, Panoutsopoulou, Kalliope, Bustamante, Mariona, Penninx, Brenda W J H, Murabito, Joanne, Torrent, Maties, Dedoussis, George V, Kiess, Wieland, Boomsma, Dorret I, Pennell, Craig E, Raitakari, Olli T, Hyppönen, Elina, Davey Smith, George, Ripatti, Samuli, McCarthy, Mark I, Widén, Elisabeth
Published in Human molecular genetics

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

by Freathy, Rachel M, Kazeem, Gbenga R, Morris, Richard W, Johnson, Paul C D, Paternoster, Lavinia, Ebrahim, Shah, Hattersley, Andrew T, Hill, Anita, Hingorani, Aroon D, Holst, Claus, Jefferis, Barbara J, Kring, Sofia I I, Mooser, Vincent, Padmanabhan, Sandosh, Preisig, Martin, Ring, Susan M, Sattar, Naveed, Upton, Mark N, Vollenweider, Peter, Waeber, Gerard, Sørensen, Thorkild I A, Frayling, Timothy M, Watt, Graham, Lawlor, Debbie A, Whincup, Peter H, Tozzi, Federica, Davey Smith, George, Munafò, Marcus
Published in International journal of epidemiology

Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations

by Guo, Xiuqing, Bis, Joshua C., Yang, Min-Lee, Ehret, Georg, Sijbrands, Eric J., Eiriksdottir, Gudny, Pihur, Vasyl, Vasan, Ramachandran S., Gateva, Vesela, Tobin, Martin D., Bochud, Murielle, Zhao, Jing Hua, Heath, Simon C., Eyheramendy, Susana, Zhang, Feng, Farrall, Martin, Wallace, Chris, Khaw, Kay-Tee, Nilsson, Peter, Polidoro, Silvia, Grobbee, Diederick E., Onland-Moret, N. Charlotte, Teumer, Alexander, Luan, Jian’an, Burton, Paul R., McArdle, Wendy L., Brown, Morris, Newhouse, Stephen J., Webster, John, Zeggini, Eleftheria, Bergmann, Sven, Song, Kijoung, Waeber, Gerard, Yuan, Xin, Groop, Leif, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Romanazzi, Valeria, Vineis, Paolo, Luben, Robert N., Crawford, Gabriel J., Boehnke, Michael, Collins, Francis S., Jackson, Anne U., Stringham, Heather M., Morken, Mario A., Gieger, Christian, Wichmann, H. Erich, O’Donnell, Christopher J., Siscovick, David S., O’Reilly, Paul F., Peltonen, Leena, Pouta, Anneli, van Gilst, Wiek H., Clarke, Robert, Goel, Anuj, Syvänen, Ann-Christine, Scheet, Paul, Scuteri, Angelo, Ernst, Florian, Felix, Stephan B., Lorbeer, Roberto, Völker, Uwe, Hercberg, Serge, Zeleneka, Diana, Deloukas, Panos, Soranzo, Nicole, Zhai, Guangju, Laakso, Markku, Forouhi, Nita G., Völzke, Henry, Numans, Mattijs E., Navis, Gerjan, Paterson, Andrew D., Bandinelli, Stefania, Spector, Tim D., Altshuler, David, Strachan, David P., Jarvelin, Marjo-Riitta, Melander, Olle, Loos, Ruth J.F., Caulfield, Mark, Raffel, Leslie J., Amin, Najaf, Rotter, Jerome I., Launer, Lenore J., Caulfield, Mark, Morrison, Alanna C., Li, Guo, Harris, Tamara B., Zhang, He, Siscovick, David S., Gao, Wei, Rivadeneira, Fernando, Willer, Cristen J., Huo, Yong, Palmas, Walter, van Duijn, Cornelia, Fornage, Myriam
Published in American journal of human genetics

Genetic Architecture of Ambulatory Blood Pressure in the General Population: Insights From Cardiovascular Gene-Centric Array

by Tomaszewski, Maciej, Debiec, Radoslaw, Braund, Peter S, Nelson, Christopher P, Hardwick, Robert, Christofidou, Paraskevi, Denniff, Matthew, Codd, Veryan, Rafelt, Suzanne, van der Harst, Pim, Waterworth, Dawn, Song, Kijoung, Vollenweider, Peter, Waeber, Gerard, Zukowska-Szczechowska, Ewa, Burton, Paul R, Mooser, Vincent, Charchar, Fadi J, Thompson, John R, Tobin, Martin D, Samani, Nilesh J
Published in Hypertension (Dallas, Tex. 1979)