Whole-genome sequencing of the world's oldest people

by Gierman, Hinco J, Fortney, Kristen, Roach, Jared C, Coles, Natalie S, Li, Hong, Glusman, Gustavo, Markov, Glenn J, Smith, Justin D, Hood, Leroy, Coles, L Stephen, Kim, Stuart K
Published in PloS one

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

by Papadimitriou, Nikos, Dimou, Niki, Tsilidis, Konstantinos K, Banbury, Barbara, Martin, Richard M, Lewis, Sarah J, Kazmi, Nabila, Robinson, Timothy M, Albanes, Demetrius, Aleksandrova, Krasimira, Berndt, Sonja I, Timothy Bishop, D, Brenner, Hermann, Buchanan, Daniel D, Bueno-de-Mesquita, Bas, Campbell, Peter T, Castellví-Bel, Sergi, Chan, Andrew T, Chang-Claude, Jenny, Ellingjord-Dale, Merete, Figueiredo, Jane C, Gallinger, Steven J, Giles, Graham G, Giovannucci, Edward, Gruber, Stephen B, Gsur, Andrea, Hampe, Jochen, Hampel, Heather, Harlid, Sophia, Harrison, Tabitha A, Hoffmeister, Michael, Hopper, John L, Hsu, Li, María Huerta, José, Huyghe, Jeroen R, Jenkins, Mark A, Keku, Temitope O, Kühn, Tilman, La Vecchia, Carlo, Le Marchand, Loic, Li, Christopher I, Li, Li, Lindblom, Annika, Lindor, Noralane M, Lynch, Brigid, Markowitz, Sanford D, Masala, Giovanna, May, Anne M, Milne, Roger, Monninkhof, Evelyn, Moreno, Lorena, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Perduca, Vittorio, Pharoah, Paul D P, Platz, Elizabeth A, Potter, John D, Rennert, Gad, Riboli, Elio, Sánchez, Maria-Jose, Schmit, Stephanie L, Schoen, Robert E, Severi, Gianluca, Sieri, Sabina, Slattery, Martha L, Song, Mingyang, Tangen, Catherine M, Thibodeau, Stephen N, Travis, Ruth C, Trichopoulou, Antonia, Ulrich, Cornelia M, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Vodicka, Pavel, White, Emily, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Peters, Ulrike, Gunter, Marc J, Murphy, Neil
Published in Nature communications

The upper limb Physiological Profile Assessment: Description, reliability, normative values and criterion validity

by Ingram, Lewis A, Butler, Annie A, Walsh, Lee D, Brodie, Matthew A, Lord, Stephen R, Gandevia, Simon C
Published in PloS one

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

by Pardi, Norbert, Hogan, Michael J, Pelc, Rebecca S, Muramatsu, Hiromi, Andersen, Hanne, DeMaso, Christina R, Dowd, Kimberly A, Sutherland, Laura L, Scearce, Richard M, Parks, Robert, Wagner, Wendeline, Granados, Alex, Greenhouse, Jack, Walker, Michelle, Willis, Elinor, Yu, Jae-Sung, McGee, Charles E, Sempowski, Gregory D, Mui, Barbara L, Tam, Ying K, Huang, Yan-Jang, Vanlandingham, Dana, Holmes, Veronica M, Balachandran, Harikrishnan, Sahu, Sujata, Lifton, Michelle, Higgs, Stephen, Hensley, Scott E, Madden, Thomas D, Hope, Michael J, Karikó, Katalin, Santra, Sampa, Graham, Barney S, Lewis, Mark G, Pierson, Theodore C, Haynes, Barton F, Weissman, Drew
Published in Nature (London)

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

by Do, Ron, Stitziel, Nathan O, Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A, Peloso, Gina M, Auer, Paul L, Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N, DePristo, Mark A, Roberts, Robert, Stewart, Alexander F R, Saleheen, Danish, Danesh, John, Epstein, Stephen E, Sivapalaratnam, Suthesh, Hovingh, G Kees, Kastelein, John J, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H, Kraus, William E, Davies, Robert, Nikpay, Majid, Johansen, Christopher T, Wang, Jian, Hegele, Robert A, Hechter, Eliana, Marz, Winfried, Kleber, Marcus E, Huang, Jie, Johnson, Andrew D, Li, Mingyao, Burke, Greg L, Gross, Myron, Liu, Yongmei, Assimes, Themistocles L, Heiss, Gerardo, Lange, Ethan M, Folsom, Aaron R, Taylor, Herman A, Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F, Yin, Wu, Rivas, Manuel A, Donnelly, Peter, Rossouw, Jacques E, Psaty, Bruce M, Herrington, David M, Wilson, James G, Rich, Stephen S, Bamshad, Michael J, Tracy, Russell P, Cupples, L Adrienne, Rader, Daniel J, Reilly, Muredach P, Spertus, John A, Cresci, Sharon, Hartiala, Jaana, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, Reiner, Alex P, Carlson, Christopher S, Kooperberg, Charles, Jackson, Rebecca D, Boerwinkle, Eric, Lander, Eric S, Schwartz, Stephen M, Siscovick, David S, McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R, Watkins, Hugh, Nickerson, Deborah A, Ardissino, Diego, Sunyaev, Shamil R, O'Donnell, Christopher J, Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar
Published in Nature (London)

Quantitative serial MRI of the treated fibroid uterus

by Munro, Kirsty I, Thrippleton, Michael J, Williams, Alistair R W, McKillop, Graham, Walker, Jane, Horne, Andrew W, Newby, David E, Anderson, Richard A, Semple, Scott I, Marshall, Ian, Lewis, Steff C, Millar, Robert P, Bastin, Mark E, Critchley, Hilary O D
Published in PloS one

The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments

by Grieshaber-Bouyer, Ricardo, Radtke, Felix A, Cunin, Pierre, Stifano, Giuseppina, Levescot, Anaïs, Vijaykumar, Brinda, Nelson-Maney, Nathan, Blaustein, Rachel B, Monach, Paul A, Nigrovic, Peter A
Published in Nature communications

Somatic mutations affect key pathways in lung adenocarcinoma

by Meyerson, Matthew, Wilson, Richard K, Ding, Li, Getz, Gad, Wheeler, David A, Mardis, Elaine R, McLellan, Michael D, Cibulskis, Kristian, Sougnez, Carrie, Greulich, Heidi, Muzny, Donna M, Morgan, Margaret B, Fulton, Lucinda, Fulton, Robert S, Zhang, Qunyuan, Wendl, Michael C, Lawrence, Michael S, Larson, David E, Chen, Ken, Dooling, David J, Sabo, Aniko, Hawes, Alicia C, Shen, Hua, Jhangiani, Shalini N, Lewis, Lora R, Hall, Otis, Zhu, Yiming, Mathew, Tittu, Ren, Yanru, Yao, Jiqiang, Scherer, Steven E, Clerc, Kerstin, Metcalf, Ginger A, Ng, Brian, Milosavljevic, Aleksandar, Gonzalez-Garay, Manuel L, Osborne, John R, Meyer, Rick, Shi, Xiaoqi, Tang, Yuzhu, Koboldt, Daniel C, Lin, Ling, Abbott, Rachel, Miner, Tracie L, Pohl, Craig, Fewell, Ginger, Haipek, Carrie, Schmidt, Heather, Dunford-Shore, Brian H, Kraja, Aldi, Crosby, Seth D, Sawyer, Christopher S, Vickery, Tammi, Sander, Sacha, Robinson, Jody, Winckler, Wendy, Baldwin, Jennifer, Chirieac, Lucian R, Dutt, Amit, Fennell, Tim, Hanna, Megan, Johnson, Bruce E, Onofrio, Robert C, Thomas, Roman K, Tonon, Giovanni, Weir, Barbara A, Zhao, Xiaojun, Ziaugra, Liuda, Zody, Michael C, Giordano, Thomas, Orringer, Mark B, Roth, Jack A, Spitz, Margaret R, Wistuba, Ignacio I, Ozenberger, Bradley, Good, Peter J, Chang, Andrew C, Beer, David G, Watson, Mark A, Ladanyi, Marc, Broderick, Stephen, Yoshizawa, Akihiko, Travis, William D, Pao, William, Province, Michael A, Weinstock, George M, Varmus, Harold E, Gabriel, Stacey B, Lander, Eric S, Gibbs, Richard A
Published in Nature

Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment

by Sun, Hua, Cao, Song, Mashl, R Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C, Davies, Sherri R, Bailey, Matthew H, Primeau, Tina M, Hoog, Jeremy, Mudd, Jacqueline L, Dean, 2nd, Dennis A, Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A, Jayasinghe, Reyka G, Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V, Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A, Ma, Cynthia X, Aft, Rebecca, Fuh, Katherine C, Schwarz, Julie K, Zevallos, Jose P, Puram, Sidharth V, Dipersio, John F, Davis-Dusenbery, Brandi, Ellis, Matthew J, Lewis, Michael T, Davies, Michael A, Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A, Welm, Alana L, Welm, Bryan E, Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C, Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H, Moscow, Jeffrey A, Evrard, Yvonne A, Chuang, Jeffrey H, Raphael, Benjamin J, Ding, Li
Published in Nature communications

Cost-effectiveness of collaborative care for depression in UK primary care: economic evaluation of a randomised controlled trial (CADET)

by Green, Colin, Richards, David A, Hill, Jacqueline J, Gask, Linda, Lovell, Karina, Chew-Graham, Carolyn, Bower, Peter, Cape, John, Pilling, Stephen, Araya, Ricardo, Kessler, David, Bland, J Martin, Gilbody, Simon, Lewis, Glyn, Manning, Chris, Hughes-Morley, Adwoa, Barkham, Michael
Published in PloS one

Insights into social insects from the genome of the honeybee Apis mellifera [Erratum: 2006 Nov. 23, v. 444, no. 7118, p. 512.]

by Weinstock, George M, Robinson, Gene E, Gibbs, Richard A, Worley, Kim C, Evans, Jay D, Maleszka, Ryszard, Robertson, Hugh M, Weaver, Daniel B, Beye, Martin, Bork, Peer, Elsik, Christine G
Published in Nature

Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection

by Ahuja, Sunil K, Manoharan, Muthu Saravanan, Lee, Grace C, McKinnon, Lyle R, Meunier, Justin A, Steri, Maristella, Harper, Nathan, Fiorillo, Edoardo, Smith, Alisha M, Restrepo, Marcos I, Branum, Anne P, Bottomley, Matthew J, Orrù, Valeria, Jimenez, Fabio, Carrillo, Andrew, Pandranki, Lavanya, Winter, Caitlyn A, Winter, Lauryn A, Gaitan, Alvaro A, Moreira, Alvaro G, Walter, Elizabeth A, Silvestri, Guido, King, Christopher L, Zheng, Yong-Tang, Zheng, Hong-Yi, Kimani, Joshua, Blake Ball, T, Plummer, Francis A, Fowke, Keith R, Harden, Paul N, Wood, Kathryn J, Ferris, Martin T, Lund, Jennifer M, Heise, Mark T, Garrett, Nigel, Canady, Kristen R, Abdool Karim, Salim S, Little, Susan J, Gianella, Sara, Smith, Davey M, Letendre, Scott, Richman, Douglas D, Cucca, Francesco, Trinh, Hanh, Sanchez-Reilly, Sandra, Hecht, Joan M, Cadena Zuluaga, Jose A, Anzueto, Antonio, Pugh, Jacqueline A, Agan, Brian K, Root-Bernstein, Robert, Clark, Robert A, Okulicz, Jason F, He, Weijing
Published in Nature communications

Durable multitransgene expression in vivo using systemic, nonviral DNA delivery

by Handumrongkul, Chakkrapong, Ye, Alice L, Chmura, Stephen A, Soroceanu, Liliana, Mack, Marissa, Ice, Ryan J, Thistle, Robert, Myers, Methawee, Ursu, Sarah J, Liu, Yong, Kashani-Sabet, Mohammed, Heath, Timothy D, Liggitt, Denny, Lewis, David B, Debs, Robert
Published in Science advances

Determinants of mosaic chromosomal alteration fitness

by Pershad, Yash, Mack, Taralynn, Poisner, Hannah, Jakubek, Yasminka A, Stilp, Adrienne M, Mitchell, Braxton D, Lewis, Joshua P, Boerwinkle, Eric, Loos, Ruth J F, Chami, Nathalie, Wang, Zhe, Barnes, Kathleen, Pankratz, Nathan, Fornage, Myriam, Redline, Susan, Psaty, Bruce M, Bis, Joshua C, Shojaie, Ali, Silverman, Edwin K, Cho, Michael H, Yun, Jeong H, DeMeo, Dawn, Levy, Daniel, Johnson, Andrew D, Mathias, Rasika A, Taub, Margaret A, Arnett, Donna, North, Kari E, Raffield, Laura M, Carson, April P, Doyle, Margaret F, Rich, Stephen S, Rotter, Jerome I, Guo, Xiuqing, Cox, Nancy J, Roden, Dan M, Franceschini, Nora, Desai, Pinkal, Reiner, Alex P, Auer, Paul L, Scheet, Paul A, Jaiswal, Siddhartha, Weinstock, Joshua S, Bick, Alexander G
Published in Nature communications

Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

by Low, Walter C, Lewis, Peter R, Terri Bunch, S, Dunnett, Stephen B, Thomas, Stephen R, Iversen, Susan D, Björklund, Anders, Stenevi, Ulf
Published in Nature (London)