Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15 by Inoue, Satoshi, Hao, Zhenyue, Elia, Andrew J, Cescon, David, Zhou, Lily, Silvester, Jennifer, Snow, Bryan, Harris, Isaac S, Sasaki, Masato, Li, Wanda Y, Itsumi, Momoe, Yamamoto, Kazuo, Ueda, Takeshi, Dominguez-Brauer, Carmen, Gorrini, Chiara, Chio, Iok In Christine, Haight, Jillian, You-Ten, Annick, McCracken, Susan, Wakeham, Andrew, Ghazarian, Danny, Penn, Linda J Z, Melino, Gerry, Mak, Tak W

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection by Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M., Rezelj, Veronica V., Correa Marrero, Miguel, Polacco, Benjamin J., Melnyk, James E., Ulferts, Svenja, Kaake, Robyn M., Batra, Jyoti, Richards, Alicia L., Stevenson, Erica, Gordon, David E., Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M., Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E., Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z., Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher J.P., Gaulton, Anna, Manners, Emma J., Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K., McBride, Timothy, O’Neal, Michael C., Cai, Yiming, Chang, Jason C.J., Broadhurst, David J., Klippsten, Saker, De wit, Emmie, Leach, Andrew R., Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R., Mullins, R. Dyche, Fischer, Elizabeth R., Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R., Shokat, Kevan M., Swaney, Danielle L., Beltrao, Pedro, Krogan, Nevan J.

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Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability by Zhan, Zhiyan, Song, Lili, Zhang, Weiwei, Gu, Haihui, Cheng, Haizi, Zhang, Yingwen, Yang, Yi, Ji, Guangzhen, Feng, Haizhong, Cheng, Tao, Li, Yanxin

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Serpine 1 induces alveolar type II cell senescence through activating p53‐p21‐Rb pathway in fibrotic lung disease by Jiang, Chunsun, Liu, Gang, Luckhardt, Tracy, Antony, Veena, Zhou, Yong, Carter, A. Brent, Thannickal, Victor J., Liu, Rui‐Ming

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Inhibitor of Apoptosis Proteins Determines Glioblastoma Stem‐Like Cell Fate in an Oxygen‐Dependent Manner by Soubéran, Aurélie, Cappaï, Jessica, Chocry, Mathieu, Nuccio, Christopher, Raujol, Julie, Colin, Carole, Lafitte, Daniel, Kovacic, Hervé, Quillien, Véronique, Baeza‐Kallee, Nathalie, Rougon, Geneviève, Figarella‐Branger, Dominique, Tchoghandjian, Aurélie

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Procyanidin‐B2 enriched fraction of cinnamon acts as a proteasome inhibitor and anti‐proliferative agent in human prostate cancer cells by Gopalakrishnan, Srividya, Ediga, Harshavardhana H., Reddy, S. Sreenivasa, Reddy, G. Bhanuprakash, Ismail, Ayesha

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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy by Fang, Yong, McGrail, Daniel J, Sun, Chaoyang, Labrie, Marilyne, Chen, Xiaohua, Zhang, Dong, Ju, Zhenlin, Vellano, Christopher P, Lu, Yiling, Li, Yongsheng, Jeong, Kang Jin, Ding, Zhiyong, Liang, Jiyong, Wang, Steven W, Dai, Hui, Lee, Sanghoon, Sahni, Nidhi, Mercado-Uribe, Imelda, Kim, Tae-Beom, Chen, Ken, Lin, Shiaw-Yih, Peng, Guang, Westin, Shannon N, Liu, Jinsong, O'Connor, Mark J, Yap, Timothy A, Mills, Gordon B

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Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases by Xu, Wei, Yang, Hui, Liu, Ying, Yang, Ying, Wang, Ping, Kim, Se-Hee, Ito, Shinsuke, Yang, Chen, Wang, Pu, Xiao, Meng-Tao, Liu, Li-xia, Jiang, Wen-qing, Liu, Jing, Zhang, Jin-ye, Wang, Bin, Frye, Stephen, Zhang, Yi, Xu, Yan-hui, Lei, Qun-ying, Guan, Kun-Liang, Zhao, Shi-min, Xiong, Yue

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Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs) by Rathore, Rama, McCallum, Jennifer E., Varghese, Elizabeth, Florea, Ana-Maria, Büsselberg, Dietrich

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Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells by Liu, Jihao, Chen, Zhuo, Huang, Mingdong, Tang, Shuzhi, Wang, Qianchao, Hu, Ping, Gupta, Pranav, Ashby, Charles R., Chen, Zhe-Sheng, Zhang, Lei

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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling by Hrdinka, Matous, Schlicher, Lisa, Dai, Bing, Pinkas, Daniel M, Bufton, Joshua C, Picaud, Sarah, Ward, Jennifer A, Rogers, Catherine, Suebsuwong, Chalada, Nikhar, Sameer, Cuny, Gregory D, Huber, Kilian VM, Filippakopoulos, Panagis, Bullock, Alex N, Degterev, Alexei, Gyrd‐Hansen, Mads

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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity by Gupta, Rajat, Somyajit, Kumar, Narita, Takeo, Maskey, Elina, Stanlie, Andre, Kremer, Magdalena, Typas, Dimitris, Lammers, Michael, Mailand, Niels, Nussenzweig, Andre, Lukas, Jiri, Choudhary, Chunaram

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A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants by Gabrielsen, Mads, Buetow, Lori, Nakasone, Mark A., Ahmed, Syed Feroj, Sibbet, Gary J., Smith, Brian O., Zhang, Wei, Sidhu, Sachdev S., Huang, Danny T.

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The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs by Zhu, Yi, Tchkonia, Tamara, Pirtskhalava, Tamar, Gower, Adam C., Ding, Husheng, Giorgadze, Nino, Palmer, Allyson K., Ikeno, Yuji, Hubbard, Gene B., Lenburg, Marc, O'Hara, Steven P., LaRusso, Nicholas F., Miller, Jordan D., Roos, Carolyn M., Verzosa, Grace C., LeBrasseur, Nathan K., Wren, Jonathan D., Farr, Joshua N., Khosla, Sundeep, Stout, Michael B., McGowan, Sara J., Fuhrmann‐Stroissnigg, Heike, Gurkar, Aditi U., Zhao, Jing, Colangelo, Debora, Dorronsoro, Akaitz, Ling, Yuan Yuan, Barghouthy, Amira S., Navarro, Diana C., Sano, Tokio, Robbins, Paul D., Niedernhofer, Laura J., Kirkland, James L.

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Cell cycle regulation: p53-p21-RB signaling by Engeland, Kurt

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Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI by Weng, Chien-Hui, Chen, Li-Yu, Lin, Yu-Chin, Shih, Jin-Yuan, Lin, Yun-Chieh, Tseng, Ruo-Yu, Chiu, An-Chieh, Yeh, Yu-Hsuan, Liu, Chi, Lin, Yi-Ting, Fang, Jim-Min, Chen, Ching-Chow

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Targeting cellular metabolism to improve cancer therapeutics by Zhao, Y, Butler, E B, Tan, M

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An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro by Li, Wei, Wang, Hang, Kuang, Chun-yan, Zhu, Jin-kun, Yu, Yang, Qin, Zhe-xue, Liu, Jie, Huang, Lan

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Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity by Schafer, P.H., Parton, A., Capone, L., Cedzik, D., Brady, H., Evans, J.F., Man, H.-W., Muller, G.W., Stirling, D.I., Chopra, R.

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Bone-Targeted Therapies in Cancer-Induced Bone Disease by Sousa, Sofia, Clézardin, Philippe

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