Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells

by Jeong, Jaekwang, Choi, Jungmin, Kim, Wonnam, Dann, Pamela, Takyar, Farzin, Gefter, Julia V., Friedman, Peter A., Wysolmerski, John J.
Published in The Journal of biological chemistry

GARP regulates the bioavailability and activation of TGFβ

by Wang, Rui, Zhu, Jianghai, Dong, Xianchi, Shi, Minlong, Lu, Chafen, Springer, Timothy A
Published in Molecular biology of the cell

In Vitro Generation of Long-Term Repopulating Hematopoietic Stem Cells by Fibroblast Growth Factor-1

by de Haan, Gerald, Weersing, Ellen, Dontje, Bert, van Os, Ronald, Bystrykh, Leonid V., Vellenga, Edo, Miller, Geraldine
Published in Developmental cell

Evidence for Novel Functions of the Keratin Tail Emerging from a Mutation Causing Ichthyosis Hystrix

by Sprecher, Eli, Miller, Christopher J., Richard, Gabriele, Ishida-Yamamoto, Akemi, Becker, Oren M., Marekov, Lyuben, Steinert, Peter M., Neldner, Kenneth
Published in Journal of investigative dermatology

Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress

by Morita, Kei-ichi, Saitoh, Masao, Tobiume, Kei, Matsuura, Hiroshi, Enomoto, Shoji, Nishitoh, Hideki, Ichijo, Hidenori
Published in The EMBO journal

Mesenchymal Stromal Cells Express GARP/LRRC32 on Their Surface: Effects on Their Biology and Immunomodulatory Capacity

by Carrillo‐Galvez, Ana Belén, Cobo, Marién, Cuevas‐Ocaña, Sara, Gutiérrez‐Guerrero, Alejandra, Sánchez‐Gilabert, Almudena, Bongarzone, Pierpaolo, García‐Pérez, Angélica, Muñoz, Pilar, Benabdellah, Karim, Toscano, Miguel G., Martín, Francisco, Anderson, Per
Published in Stem cells (Dayton, Ohio)

SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress

by Gao, Jing, Feng, Zhihui, Wang, Xueqiang, Zeng, Mengqi, Liu, Jing, Han, Shujun, Xu, Jie, Chen, Lei, Cao, Ke, Long, Jiangang, Li, Zongfang, Shen, Weili, Liu, Jiankang
Published in Cell death and differentiation

Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors

by Ady, Visou, Perroy, Julie, Tricoire, Ludovic, Piochon, Claire, Dadak, Selma, Chen, Xiaoru, Dusart, Isabelle, Fagni, Laurent, Lambolez, Bertrand, Levenes, Carole
Published in EMBO reports

ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

by Umeda, Kazuaki, Ikenouchi, Junichi, Katahira-Tayama, Sayaka, Furuse, Kyoko, Sasaki, Hiroyuki, Nakayama, Mayumi, Matsui, Takeshi, Tsukita, Sachiko, Furuse, Mikio, Tsukita, Shoichiro
Published in Cell

GARP is a key molecule for mesenchymal stromal cell responses to TGF‐β and fundamental to control mitochondrial ROS levels

by Carrillo‐Gálvez, Ana Belén, Gálvez‐Peisl, Sheyla, González‐Correa, Juan Elías, Haro‐Carrillo, Marina, Ayllón, Verónica, Carmona‐Sáez, Pedro, Ramos‐Mejía, Verónica, Galindo‐Moreno, Pablo, Cara, Francisca E., Granados‐Principal, Sergio, Muñoz, Pilar, Martin, Francisco, Anderson, Per
Published in Stem cells translational medicine

Targeting mutant fibroblast growth factor receptors in cancer

by Greulich, Heidi, Pollock, Pamela M
Published in Trends in molecular medicine

The E3 Ubiquitin Ligase AIP4 Mediates Ubiquitination and Sorting of the G Protein-Coupled Receptor CXCR4

by Marchese, Adriano, Raiborg, Camilla, Santini, Francesca, Keen, James H, Stenmark, Harald, Benovic, Jeffrey L
Published in Developmental cell

The intestinal microenvironment in sepsis

by Fay, Katherine T., Ford, Mandy L., Coopersmith, Craig M.
Published in Biochimica et biophysica acta. Molecular basis of disease

Up-regulation of miRNA-221 inhibits hypoxia/reoxygenation-induced autophagy through the DDIT4/mTORC1 and Tp53inp1/p62 pathways

by Chen, Qiying, Zhou, Yue, Richards, A. Mark, Wang, Peipei
Published in Biochemical and biophysical research communications

Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1 +/− Mice

by Wang, Grace Ying, Wang, Joy, Mancianti, Maria-Laura, Epstein, Ervin H.
Published in Cancer cell

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

by Bernassola, Francesca, Karin, Michael, Ciechanover, Aaron, Melino, Gerry
Published in Cancer cell

GARP: a key receptor controlling FOXP3 in human regulatory T cells

by Probst‐Kepper, M., Geffers, R., Kröger, A., Viegas, N., Erck, C., Hecht, H.‐J., Lünsdorf, H., Roubin, R., Moharregh‐Khiabani, D., Wagner, K., Ocklenburg, F., Jeron, A., Garritsen, H., Arstila, T.P., Kekäläinen, E., Balling, R., Hauser, H., Buer, J., Weiss, S.
Published in Journal of cellular and molecular medicine

Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner

by Gray, Stephen, Santiago, Emerson R., Chappie, Joshua S., Cohen, Paula E.
Published in Cell reports (Cambridge)

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling

by Zhang, Xing-Ding, Baladandayuthapani, Veerabhadran, Lin, Heather, Mulligan, George, Li, Bin, Esseltine, Dixie-Lee W., Qi, Lin, Xu, Jianliang, Hunziker, Walter, Barlogie, Bart, Usmani, Saad Z., Zhang, Qing, Crowley, John, Hoering, Antje, Shah, Jatin J., Weber, Donna M., Manasanch, Elisabet E., Thomas, Sheeba K., Li, Bing-Zong, Wang, Hui-Han, Zhang, Jiexin, Kuiatse, Isere, Tang, Jin-Le, Wang, Hua, He, Jin, Yang, Jing, Milan, Enrico, Cenci, Simone, Ma, Wen-Cai, Wang, Zhi-Qiang, Davis, Richard Eric, Yang, Lin, Orlowski, Robert Z.
Published in Cancer cell

Illuminating the complexity of GPCR pathway selectivity – advances in biosensor development

by Wright, Shane C., Bouvier, Michel
Published in Current opinion in structural biology