Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses

by Lan, Yan, Yeung, Tsz-Lun, Huang, Hui, Wegener, Ansgar A, Saha, Somdutta, Toister-Achituv, Mira, Jenkins, Molly H, Chiu, Li-Ya, Lazorchak, Adam, Tarcic, Ohad, Wang, Hong, Qi, Jin, Locke, George, Kalimi, Doron, Qin, Guozhong, Marelli, Bo, Yu, Huakui, Gross, Alec W, Derner, Melissa G, Soloviev, Maria, Botte, Mathieu, Sircar, Aroop, Ma, Hong, Sood, Vanita D, Zhang, Dong, Jiang, Feng, Lo, Kin-Ming
Published in Journal for immunotherapy of cancer

A comprehensive review of SHP2 and its role in cancer

by Asmamaw, Moges Dessale, Shi, Xiao-Jing, Zhang, Li-Rong, Liu, Hong-Min
Published in Cellular oncology (Dordrecht)

SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities

by Liu, Yonglan, Zhang, Wengang, Jang, Hyunbum, Nussinov, Ruth
Published in Cellular and molecular life sciences : CMLS

ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97

by Pozner, Amir, Li, Li, Verma, Shiv Prakash, Wang, Shuxin, Barrott, Jared J, Nelson, Mary L, Yu, Jamie S E, Negri, Gian Luca, Colborne, Shane, Hughes, Christopher S, Zhu, Ju-Fen, Lambert, Sydney L, Carroll, Lara S, Smith-Fry, Kyllie, Stewart, Michael G, Kannan, Sarmishta, Jensen, Bodrie, John, Cini M, Sikdar, Saif, Liu, Hongrui, Dang, Ngoc Ha, Bourdage, Jennifer, Li, Jinxiu, Vahrenkamp, Jeffery M, Mortenson, Katelyn L, Groundland, John S, Wustrack, Rosanna, Senger, Donna L, Zemp, Franz J, Mahoney, Douglas J, Gertz, Jason, Zhang, Xiaoyang, Lazar, Alexander J, Hirst, Martin, Morin, Gregg B, Nielsen, Torsten O, Shen, Peter S, Jones, Kevin B
Published in Nature communications

Nemvaleukin alfa, a novel engineered IL-2 fusion protein, drives antitumor immunity and inhibits tumor growth in small cell lung cancer

by Pan, Yuanwang, Hao, Yuan, Han, Han, Chen, Ting, Ding, Hailin, Labbe, Kristen E, Shum, Elaine, Guidry, Kayla, Hu, Hai, Sherman, Fiona, Geng, Ke, Stephens, Janaye, Chafitz, Alison, Tang, Sittinon, Huang, Hsin-Yi, Peng, Chengwei, Almonte, Christina, Lopes, Jared E, Losey, Heather C, Winquist, Raymond J, Velcheti, Vamsidhar, Zhang, Hua, Wong, Kwok-Kin
Published in Journal for immunotherapy of cancer

The era of immunogenomics/immunopharmacogenomics

by Zewde, Makda, Kiyotani, Kazuma, Park, Jae-Hyun, Fang, Hua, Yap, Kai Lee, Yew, Poh Yin, Alachkar, Houda, Kato, Taigo, Mai, Tu H, Ikeda, Yuji, Matsuda, Tatsuo, Liu, Xiao, Ren, Lili, Deng, Boya, Harada, Makiko, Nakamura, Yusuke
Published in Journal of human genetics

Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective

by Yang, Yang, Li, Shuo, Wang, Yujiao, Zhao, Yi, Li, Qiu
Published in Signal transduction and targeted therapy

Role and mechanistic actions of protein kinase inhibitors as an effective drug target for cancer and COVID

by Narayanan, J., Tamilanban, T., Kumar, P. Senthil, Guru, Ajay, Muthupandian, Saravanan, Kathiravan, M. K., Arockiaraj, Jesu
Published in Archives of microbiology

Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells

by Shockey, W. Andrew, Kieslich, Christopher A., Wilder, Catera L., Watson, Valencia, Platt, Manu O.
Published in Cellular and molecular bioengineering

Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies

by Shah, Ashu, Chaudhary, Sanjib, Lakshmanan, Imayavaramban, Aithal, Abhijit, Kisling, Sophia G, Sorrell, Claire, Marimuthu, Saravanakumar, Gautam, Shailendra K, Rauth, Sanchita, Kshirsagar, Prakash, Cox, Jesse L, Natarajan, Gopalakrishnan, Bhatia, Rakesh, Mallya, Kavita, Rachagani, Satyanarayana, Nasser, Mohd Wasim, Ganti, Apar Kishor, Salgia, Ravi, Kumar, Sushil, Jain, Maneesh, Ponnusamy, Moorthy P, Batra, Surinder K
Published in NPJ precision oncology

Circulating tumor cells as Trojan Horse for understanding, preventing, and treating cancer: a critical appraisal

by Mentis, Alexios-Fotios A., Grivas, Petros D., Dardiotis, Efthimios, Romas, Nicholas A., Papavassiliou, Athanasios G.
Published in Cellular and molecular life sciences : CMLS

INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses

by Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P
Published in Journal for immunotherapy of cancer

Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

by Cai, Ze-Min, Li, Zi-Zhan, Zhong, Nian-Nian, Cao, Lei-Ming, Xiao, Yao, Li, Jia-Qi, Huo, Fang-Yi, Liu, Bing, Xu, Chun, Zhao, Yi, Rao, Lang, Bu, Lin-Lin
Published in Journal of nanobiotechnology

Contributions from emerging transcriptomics technologies and computational strategies for drug discovery

by Kadioglu, Onat, Efferth, Thomas
Published in Investigational new drugs

Emerging biomaterials for tumor immunotherapy

by Xiao, Minna, Tang, Qinglai, Zeng, Shiying, Yang, Qian, Yang, Xinming, Tong, Xinying, Zhu, Gangcai, Lei, Lanjie, Li, Shisheng
Published in Biomaterials research

Comparison of health-care utilization and expenditures for minimally invasive vs. open colectomy for benign disease

by Diaz, Sarah E., Lee, Yongjin F., Bastawrous, Amir L., Shih, I.-Fan, Lee, Shih-Hao, Li, Yanli, Cleary, Robert K.
Published in Surgical endoscopy

Sensitizing immune unresponsive colorectal cancers to immune checkpoint inhibitors through MAVS overexpression

by Hwang, Bin-Jin, Tsao, Li-Chung, Acharya, Chaitanya R, Trotter, Timothy, Agarwal, Pankaj, Wei, Junping, Wang, Tao, Yang, Xiao-Yi, Lei, Gangjun, Osada, Takuya, Lyerly, Herbert Kim, Morse, Michael A, Hartman, Zachary Conrad
Published in Journal for immunotherapy of cancer

TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress

by Ueno, Hiroyuki, Hoshino, Takuya, Yano, Wakako, Tsukioka, Sayaka, Suzuki, Takamasa, Hara, Shoki, Ogino, Yoshio, Chong, Khoon Tee, Suzuki, Tatsuya, Tsuji, Shingo, Itadani, Hikaru, Yamamiya, Ikuo, Otsu, Yoshihiro, Ito, Satoshi, Yonekura, Toshiya, Terasaka, Miki, Tanaka, Nozomu, Miyahara, Seiji
Published in Communications biology

A review of the clinical efficacy of FDA-approved antibody‒drug conjugates in human cancers

by Liu, Kaifeng, Li, Meijia, Li, Yudong, Li, Yutong, Chen, Zixin, Tang, Yiqi, Yang, Meitian, Deng, Guoquan, Liu, Hongwei
Published in Molecular cancer

Mechanisms of chromosomal instability (CIN) tolerance in aggressive tumors: surviving the genomic chaos

by Dhital, Brittiny, Rodriguez-Bravo, Veronica
Published in Chromosome research