Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease

by Lin, Lucy, Patel, Ealin N, Nielsen, Alexander L, Turner, Lewis D, Tepp, William H, Nguyen, Kong, Pellett, Sabine, Janda, Kim
Published in International journal of molecular sciences

Finding the gas pedal on a slow sirtuin

by Nielsen, Alexander L., Olsen, Christian A.
Published in The Journal of biological chemistry

Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach

by Turner, Lewis D, Nielsen, Alexander L, Lin, Lucy, Pellett, Sabine, Sugane, Takashi, Olson, Margaret E, Johnson, Eric A, Janda, Kim D
Published in RSC medicinal chemistry

Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay

by Shirey, Ryan J., Hart, Jonathan R., Sridharan, BanuPriya, Novick, Scott J., Turner, Lewis D., Zhou, Bin, Nielsen, Alexander L., Eubanks, Lisa M., Ueno, Lynn, Hixon, Mark S., Lairson, Luke L., Spicer, Timothy P., Scampavia, Louis D., Griffin, Patrick R., Vogt, Peter K., Janda, Kim D.
Published in Bioorganic & medicinal chemistry

Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell...

by Nielsen, Alexander L, Rajabi, Nima, Kudo, Norio, Lundø, Kathrine, Moreno-Yruela, Carlos, Bæk, Michael, Fontenas, Martin, Lucidi, Alessia, Madsen, Andreas S, Yoshida, Minoru, Olsen, Christian A
Published in RSC chemical biology

Neurotrophic Effects of Vascular Endothelial Growth Factor B and Novel Mimetic Peptides on Neurons from the Central Nervous System

by Dmytriyeva, Oksana, de Diego Ajenjo, Amaia, Lundø, Kathrine, Hertz, Henrik, Rasmussen, Kim K, Christiansen, Anders T, Klingelhofer, Jorg, Nielsen, Alexander L, Hoeber, Jan, Kozlova, Elena, Woldbye, David P. D, Pankratova, Stanislava
Published in ACS chemical neuroscience

Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

by Troelsen, Kathrin S, Bæk, Michael, Nielsen, Alexander L, Madsen, Andreas S, Rajabi, Nima, Olsen, Christian A
Published in RSC chemical biology

A Dual Pressure Linear Ion Trap Orbitrap Instrument with Very High Sequencing Speed

by Olsen, Jesper V., Schwartz, Jae C., Griep-Raming, Jens, Nielsen, Michael L., Damoc, Eugen, Denisov, Eduard, Lange, Oliver, Remes, Philip, Taylor, Dennis, Splendore, Maurizio, Wouters, Eloy R., Senko, Michael, Makarov, Alexander, Mann, Matthias, Horning, Stevan
Published in Molecular & cellular proteomics

The phylogeny of extant starfish (Asteroidea: Echinodermata) including Xyloplax, based on comparative transcriptomics

by Linchangco, Gregorio V., Foltz, David W., Reid, Rob, Williams, John, Nodzak, Conor, Kerr, Alexander M., Miller, Allison K., Hunter, Rebecca, Wilson, Nerida G., Nielsen, William J., Mah, Christopher L., Rouse, Greg W., Wray, Gregory A., Janies, Daniel A.
Published in Molecular phylogenetics and evolution

Linking microbial community structure with function: fluorescence in situ hybridization-microautoradiography and isotope arrays

by Wagner, Michael, Nielsen, Per H, Loy, Alexander, Nielsen, Jeppe L, Daims, Holger
Published in Current opinion in biotechnology

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

by Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Bjornsdottir, Gyda, Gilly, Arthur, Ingvarsson, Thorvaldur, Luetge, Almut, Lund, Sigrun H., Mangino, Massimo, Takuwa, Hiroshi, Thomas, Laurent F., Loughlin, John, Arden, Nigel, Doherty, Michael, Ollier, William E.R., Spector, Tim D., Wallis, Gillian A., Martinsen, Amy E., Fors, Egil Andreas, Hagen, Knut, Nilsen, Kristian Bernhard, Lie, Marie Udnesseter, Børte, Sigrid, Brumpton, Ben, Fritsche, Lars G., Zhou, Wei, Heuch, Ingrid, Storheim, Kjersti, Tyrpenou, Evangelos, Koukakis, Athanasios, Efstathios, Chronopoulos, Nikolaou, Vasileios S., Malizos, Konstantinos, Anastasopoulou, Lydia, Abecasis, Goncalo, Baras, Aris, Cantor, Michael, Coppola, Giovanni, Lotta, Luca A., Shuldiner, Alan, Karalis, Katia, Siminovitch, Katherine, Beechert, Christina, Forsythe, Caitlin, Fuller, Erin D., Gu, Zhenhua, Lattari, Michael, Padilla, Maria Sotiropoulos, Widom, Louis, Wolf, Sarah E., Pradhan, Manasi, Manoochehri, Kia, Bai, Xiaodong, Balasubramanian, Suganthi, Boutkov, Boris, Eom, Gisu, Habegger, Lukas, Hawes, Alicia, Maxwell, Evan K., Orelus, Max, Panea, Razvan, Polanco, Tommy, Salerno, William, Staples, Jeffrey C., Li, Dadong, Sharma, Deepika, Banerjee, Ilanjana, Locke, Adam, Haas, Mary, Akbari, Parsa, Ferreira, Manuel A.R., Jones, Marcus B., Mitnaul, Lyndon J., Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Lietman, Steven A., Samartzis, Dino, Stefansson, Kari, Uitterlinden, André G., Davey Smith, George, Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Hveem, Kristian, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Published in Cell

An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation

by Dinesen, Anders, Andersen, Veronica L., Elkhashab, Marwa, Pilati, Diego, Bech, Pernille, Fuchs, Elisabeth, Samuelsen, Torbjørn R., Winther, Alexander, Cai, Yunpeng, Märcher, Anders, Wall, Archie, Omer, Marjan, Nielsen, Jesper S., Chudasama, Vijay, Baker, James R., Gothelf, Kurt V., Wengel, Jesper, Kjems, Jørgen, Howard, Kenneth A.
Published in Bioconjugate chemistry

The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth

by Brehm, Alexander, Nielsen, Søren J., Miska, Eric A., McCance, Dennis J., Reid, Juliet L., Bannister, Andrew J., Kouzarides, Tony
Published in The EMBO journal

Systemic Corticosteroids and the Risk of Venous Thromboembolism in Patients with Severe COPD: A Nationwide Study of 30,473 Outpatients

by Rastoder, Ema, Sivapalan, Pradeesh, Eklöf, Josefin, Saeed, Mohamad Isam, Jordan, Alexander Svorre, Meteran, Howraman, Tønnesen, Louise, Biering-Sørensen, Tor, Løkke, Anders, Seersholm, Niels, Lynghøj Nielsen, Thyge, Carlsen, Jørn, Janner, Julie, Godtfredsen, Nina, Bodtger, Uffe, Laursen, Christian B., Hilberg, Ole, Knop, Filip K., Priemé, Helene, Ingebrigtsen, Truls Sylvan, Gottlieb, Vibeke, Wilcke, Jon Torgny, Stæhr Jensen, Jens Ulrik
Published in Biomedicines

Identification of dominant signaling pathways from proteomics expression data

by Zubarev, Roman A., Nielsen, Michael L., Fung, Eva M., Savitski, Mikhail M., Kel-Margoulis, Olga, Wingender, Edgar, Kel, Alexander
Published in Journal of proteomics

The acute action of ammonia on rat brain metabolism in vivo

by Hawkins, R A, Miller, A L, Nielsen, R C, Veech, R L
Published in Biochemical journal