Imbalance in the response of pre- and post-synaptic components to amyloidopathy

by Stephen, Terri-Leigh, Tamagnini, Francesco, Piegsa, Judith, Sung, Katherine, Harvey, Joshua, Oliver-Evans, Alice, Murray, Tracey K, Ahmed, Zeshan, Hutton, Michael L, Randall, Andrew, O'Neill, Michael J, Jackson, Johanna S
Published in Scientific reports

Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders

by Iturria-Medina, Yasser, Sotero, Roberto C, Toussaint, Paule J, Evans, Alan C
Published in PLoS computational biology

Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

by Vogel, Jacob W, Iturria-Medina, Yasser, Strandberg, Olof T, Smith, Ruben, Levitis, Elizabeth, Evans, Alan C, Hansson, Oskar
Published in Nature communications

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

by Escott-Price, Valentina, Harold, Denise, Jones, Lesley, Gerrish, Amy, Vedernikov, Alexey, DeStefano, Anita L, Ibrahim-Verbaas, Carla A, Bis, Joshua C, Grenier-Boley, Benjamin, Russo, Giancarlo, Smith, Albert V, Chouraki, Vincent, Thomas, Charlene, Zelenika, Diana, Kamatani, Yoichiro, Lin, Chiao-Feng, Dunstan, Melanie L, Vronskaya, Maria, Ruiz, Agustin, Bihoreau, Marie-Thérèse, Reitz, Christiane, Pasquier, Florence, Hollingworth, Paul, Hanon, Olivier, Fitzpatrick, Annette L, Becker, Tim, Gudnason, Vilmundur, Amin, Najaf, De Jager, Philip L, Johnston, Janet A, Evans, Denis, Hernández, Isabel, Goate, Alison M, Fiévet, Nathalie, Kamboh, M Ilyas, Keller, Lina, McGuinness, Bernadette, Wallon, David, Love, Seth, Gallacher, John, George-Hyslop, Peter St, Lleo, Alberto, Bayer, Anthony, Tsuang, Debby W, Yu, Lei, Spalletta, Gianfranco, Proitsi, Petra, Sorbi, Sandro, Garcia, Florentino Sanchez, Fox, Nick C, Naranjo, Maria Candida Deniz, Bosco, Paolo, Clarke, Robert, Brayne, Carol, Bonuccelli, Ubaldo, Mancuso, Michelangelo, Moebus, Susanne, Zompo, Maria Del, Maier, Wolfgang, Panza, Francesco, Caffarra, Paolo, Perry, William, Mayhaus, Manuel, Lannfelt, Lars, Pichler, Sabrina, Carrasquillo, Minerva M, Alvarez, Victoria, Valladares, Otto, Hamilton-Nelson, Kara L, Pastor, Pau, Owen, Michael J, Faber, Kelley M, Jonsson, Palmi V, O'Donovan, Michael C, Cantwell, Laura B, Blacker, Deborah, Mead, Simon, Mosley, Jr, Thomas H, de Bruijn, Renee F A G, Passmore, Peter, Brice, Alexis, Morgan, Kevin, Foroud, Tatiana M, Kukull, Walter A, Hannequin, Didier, Powell, John F, Nalls, Michael A, Ritchie, Karen, Kauwe, John S K, Riemenschneider, Matthias, Boada, Mercè, Martin, Eden R, Rujescu, Dan, Tzourio, Christophe, Hofman, Albert, Graff, Caroline, Launer, Lenore J, Van Broeckhoven, Christine, van Duijn, Cornelia M, Seshadri, Sudha
Published in PloS one

Non-coding variability at the APOE locus contributes to the Alzheimer's risk

by Zhou, Xiaopu, Chen, Yu, Mok, Kin Y, Kwok, Timothy C Y, Mok, Vincent C T, Guo, Qihao, Ip, Fanny C, Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F, Hardy, John, Fu, Amy K Y, Li, Yun, Ip, Nancy Y
Published in Nature communications

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

by Franzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael
Published in Nature communications

Multi-method analysis of MRI images in early diagnostics of Alzheimer's disease

by Wolz, Robin, Julkunen, Valtteri, Koikkalainen, Juha, Niskanen, Eini, Zhang, Dong Ping, Rueckert, Daniel, Soininen, Hilkka, Lötjönen, Jyrki
Published in PloS one

Robust Identification of Alzheimer's Disease subtypes based on cortical atrophy patterns

by Park, Jong-Yun, Na, Han Kyu, Kim, Sungsoo, Kim, Hyunwook, Kim, Hee Jin, Seo, Sang Won, Na, Duk L, Han, Cheol E, Seong, Joon-Kyung
Published in Scientific reports

Standardization of analysis sets for reporting results from ADNI MRI data

by Wyman, Bradley T, Harvey, Danielle J, Crawford, Karen, Bernstein, Matt A, Carmichael, Owen, Cole, Patricia E, Crane, Paul K, DeCarli, Charles, Fox, Nick C, Gunter, Jeffrey L, Hill, Derek, Killiany, Ronald J, Pachai, Chahin, Schwarz, Adam J, Schuff, Norbert, Senjem, Matthew L, Suhy, Joyce, Thompson, Paul M, Weiner, Michael, Jack, Clifford R
Published in Alzheimer's & dementia

Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

by de Matos, Ana M., Martins, Alice, Man, Teresa, Evans, David, Walter, Magnus, Oliveira, Maria Conceição, López, Óscar, Fernandez-Bolaños, José G., Dätwyler, Philipp, Ernst, Beat, Macedo, M. Paula, Contino, Marialessandra, Colabufo, Nicola A., Rauter, Amélia P.
Published in Pharmaceuticals (Basel, Switzerland)

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

by Franzmeier, Nicolai, Suárez-Calvet, M, Frontzkowski, Lukas, Moore, Annah, Hohman, Timothy J, Morenas-Rodriguez, Estrella, Nuscher, Brigitte, Shaw, Leslie, Trojanowski, John Q, Dichgans, Martin, Kleinberger, Gernot, Haass, Christian, Ewers, Michael
Published in Molecular neurodegeneration

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

by Huang, Meiyan, Yang, Wei, Feng, Qianjin, Chen, Wufan
Published in Scientific reports

Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease

by Reitz, Christiane, Tosto, Giuseppe, Mayeux, Richard, Luchsinger, Jose A
Published in PloS one

Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer's Disease

by Hao, Xiaoke, Li, Chanxiu, Du, Lei, Yao, Xiaohui, Yan, Jingwen, Risacher, Shannon L, Saykin, Andrew J, Shen, Li, Zhang, Daoqiang
Published in Scientific reports

Rates of decline in Alzheimer disease decrease with age

by Holland, Dominic, Desikan, Rahul S, Dale, Anders M, McEvoy, Linda K
Published in PloS one

Plasma based markers of [11C] PiB-PET brain amyloid burden

by Kiddle, Steven John, Thambisetty, Madhav, Simmons, Andrew, Riddoch-Contreras, Joanna, Hye, Abdul, Westman, Eric, Pike, Ian, Ward, Malcolm, Johnston, Caroline, Lupton, Michelle Katharine, Lunnon, Katie, Soininen, Hilkka, Kloszewska, Iwona, Tsolaki, Magda, Vellas, Bruno, Mecocci, Patrizia, Lovestone, Simon, Newhouse, Stephen, Dobson, Richard
Published in PloS one

Generative FDG-PET and MRI model of aging and disease progression in Alzheimer's disease

by Dukart, Juergen, Kherif, Ferath, Mueller, Karsten, Adaszewski, Stanislaw, Schroeter, Matthias L, Frackowiak, Richard S J, Draganski, Bogdan
Published in PLoS computational biology

Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset

by Johnstone, Daniel, Milward, Elizabeth A, Berretta, Regina, Moscato, Pablo
Published in PloS one

Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

by Swaminathan, Shanker, Huentelman, Matthew J, Corneveaux, Jason J, Myers, Amanda J, Faber, Kelley M, Foroud, Tatiana, Mayeux, Richard, Shen, Li, Kim, Sungeun, Turk, Mari, Hardy, John, Reiman, Eric M, Saykin, Andrew J
Published in PloS one

Sex Modulates the Pathological Aging Effect on Caudate Functional Connectivity in Mild Cognitive Impairment

by Yang, Zhengshi, Caldwell, Jessica Z K, Cummings, Jeffrey L, Ritter, Aaron, Kinney, Jefferson W, Cordes, Dietmar
Published in Frontiers in psychiatry