Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial

by Migden, Michael R, Dr, Guminski, Alexander, PhD, Gutzmer, Ralf, Prof, Dirix, Luc, MD, Lewis, Karl D, MD, Combemale, Patrick, MD, Herd, Robert M, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, Prof, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J, Prof, Schulze, Hans-Joachim, MD, Plummer, Ruth, Prof, Chang, Anne Lynn S, MD, Cornélis, Frank, MD, Lear, John T, MD, Sellami, Dalila, MD, Dummer, Reinhard, Prof
Published in The lancet oncology

The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell...

by Dummer, Reinhard, MD, Guminski, Alexander, MD, PhD, Gutzmer, Ralf, MD, Dirix, Luc, MD, Lewis, Karl D., MD, Combemale, Patrick, MD, Herd, Robert M., MD, Kaatz, Martin, MD, Loquai, Carmen, MD, Stratigos, Alexander J., MD, Schulze, Hans-Joachim, MD, Plummer, Ruth, MD, Gogov, Sven, MD, Pallaud, Celine, PhD, Yi, Tingting, PhD, Mone, Manisha, PhD, Chang, Anne Lynn S., MD, Cornélis, Frank, MD, Kudchadkar, Ragini, MD, Trefzer, Uwe, MD, Lear, John T., MD, Sellami, Dalila, MD, Migden, Michael R., MD
Published in Journal of the American Academy of Dermatology

Disentangling the Association between Statins, Cholesterol, and Colorectal Cancer: A Nested Case-Control Study

by Mamtani, Ronac, Lewis, James D, Scott, Frank I, Ahmad, Tariq, Goldberg, David S, Datta, Jashodeep, Yang, Yu-Xiao, Boursi, Ben
Published in PLoS medicine

Operative Versus Nonoperative Treatment for Adult Symptomatic Lumbar Scoliosis

by Kelly, Michael P, Lurie, Jon D, Yanik, Elizabeth L, Shaffrey, Christopher I, Baldus, Christine R, Boachie-Adjei, Oheneba, Buchowski, Jacob M, Carreon, Leah Y, Crawford, Charles H, Edwards, Charles, Errico, Thomas J, Glassman, Steven D, Gupta, Munish C, Lenke, Lawrence G, Lewis, Stephen J, Kim, Han Jo, Koski, Tyler, Parent, Stefan, Schwab, Frank J, Smith, Justin S, Zebala, Lukas P, Bridwell, Keith H
Published in Journal of bone and joint surgery. American volume

Olfactory Dysfunction and Depression Trajectories in Community-Dwelling Older Adults

by Kamath, Vidyulata, Jiang, Kening, Manning, Kevin J, Mackin, R Scott, Walker, Keenan A, Powell, Danielle, Lin, Frank R, Chen, Honglei, Brenowitz, Willa D, Yaffe, Kristine, Simonsick, Eleanor M, Deal, Jennifer A
Published in The journals of gerontology. Series A, Biological sciences and medical sciences

Elevated Levels of Serum Glial Fibrillary Acidic Protein Breakdown Products in Mild and Moderate Traumatic Brain Injury Are Associated With Intracranial Lesions and Neurosurgical I...

by Papa, Linda, MDCM, MSc, Lewis, Lawrence M., MD, Falk, Jay L., MD, Zhang, Zhiqun, PhD, Silvestri, Salvatore, MD, Giordano, Philip, MD, Brophy, Gretchen M., PharmD, Demery, Jason A., PhD, Dixit, Neha K., PhD, Ferguson, Ian, BA, Liu, Ming Cheng, MD, MS, Mo, Jixiang, PhD, Akinyi, Linnet, MS, Schmid, Kara, PhD, Mondello, Stefania, MD, PhD, Robertson, Claudia S., MD, Tortella, Frank C., PhD, Hayes, Ronald L., PhD, Wang, Kevin K.W., PhD
Published in Annals of emergency medicine

Synovitis and the risk of knee osteoarthritis: the MOST Study

by Felson, D.T, Niu, J, Neogi, T, Goggins, J, Nevitt, M.C, Roemer, F, Torner, J, Lewis, C.E, Guermazi, A
Published in Osteoarthritis and cartilage

Ecallantide for the Acute Treatment of Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema: A Multicenter, Randomized, Controlled Trial

by Lewis, Lawrence M., MD, Graffeo, Charles, MD, Crosley, Pascal, DO, Klausner, Howard A., MD, Clark, Carol L., MD, Frank, Anthony, MD, Miner, James, MD, Iarrobino, Ryan, BA, Chyung, Yung, MD
Published in Annals of emergency medicine

Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial

by Lederle, Frank A, Freischlag, Julie A, Kyriakides, Tassos C, Padberg, Frank T, Matsumura, Jon S, Kohler, Ted R, Lin, Peter H, Jean-Claude, Jessie M, Cikrit, Dolores F, Swanson, Kathleen M, Peduzzi, Peter N, Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group, for the
Published in JAMA : the journal of the American Medical Association

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

by The REMAP-CAP Investigators
Published in New England Journal of Medicine

Moderation of dietary sodium potentiates the renal and cardiovascular protective effects of angiotensin receptor blockers

by Heerspink, Hiddo J. Lambers, Holtkamp, Frank A., Parving, Hans-Henrik, Navis, Gerjan J., Lewis, Julia B., Ritz, Eberhard, de Graeff, Pieter A., de Zeeuw, Dick
Published in Kidney international

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

by The REMAP-CAP, ACTIV-4a, and ATTACC Investigators
Published in New England Journal of Medicine

Secular trends in small-bowel obstruction and adhesiolysis in the United States: 1988–2007

by Scott, Frank I., M.D, Osterman, Mark T., M.D., M.S.C.E, Mahmoud, Najjia N., M.D, Lewis, James D., M.D., M.S.C.E
Published in The American journal of surgery

Knee malalignment is associated with an increased risk for incident and enlarging bone marrow lesions in the more loaded compartments: the MOST study

by Hayashi, D, Englund, M, Roemer, F.W, Niu, J, Sharma, L, Felson, D.T, Crema, M.D, Marra, M.D, Segal, N.A, Lewis, C.E, Nevitt, M.C, Guermazi, A
Published in Osteoarthritis and cartilage

Heterogeneity of cartilage damage in Kellgren and Lawrence grade 2 and 3 knees: the MOST study

by Roemer, F.W., Felson, D.T., Stefanik, J.J., Rabasa, G., Wang, N., Crema, M.D., Neogi, T., Nevitt, M.C., Torner, J., Lewis, C.E., Peloquin, C., Guermazi, A.
Published in Osteoarthritis and cartilage

Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively defined cartilage thick...

by Guermazi, A, Eckstein, F, Hayashi, D, Roemer, F.W, Wirth, W, Yang, T, Niu, J, Sharma, L, Nevitt, M.C, Lewis, C.E, Torner, J, Felson, D.T
Published in Osteoarthritis and cartilage

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

by The ATTACC, ACTIV-4a, and REMAP-CAP Investigators
Published in New England Journal of Medicine

Association of Cardiometabolic Multimorbidity With Mortality

by Di Angelantonio, Emanuele, Kaptoge, Stephen, Wormser, David, Willeit, Peter, Butterworth, Adam S, Bansal, Narinder, O’Keeffe, Linda M, Gao, Pei, Wood, Angela M, Burgess, Stephen, Freitag, Daniel F, Pennells, Lisa, Peters, Sanne A, Hart, Carole L, Håheim, Lise Lund, Gillum, Richard F, Nordestgaard, Børge G, Psaty, Bruce M, Yeap, Bu B, Knuiman, Matthew W, Nietert, Paul J, Kauhanen, Jussi, Salonen, Jukka T, Kuller, Lewis H, Simons, Leon A, van der Schouw, Yvonne T, Barrett-Connor, Elizabeth, Selmer, Randi, Crespo, Carlos J, Rodriguez, Beatriz, Verschuren, W. M. Monique, Salomaa, Veikko, Svärdsudd, Kurt, van der Harst, Pim, Björkelund, Cecilia, Wilhelmsen, Lars, Wallace, Robert B, Brenner, Hermann, Amouyel, Philippe, Barr, Elizabeth L. M, Iso, Hiroyasu, Onat, Altan, Trevisan, Maurizio, D'Agostino, Ralph B, Cooper, Cyrus, Kavousi, Maryam, Welin, Lennart, Roussel, Ronan, Hu, Frank B, Sato, Shinichi, Davidson, Karina W, Howard, Barbara V, Leening, Maarten J. G, Rosengren, Annika, Dörr, Marcus, Deeg, Dorly J. H, Kiechl, Stefan, Stehouwer, Coen D. A, Nissinen, Aulikki, Giampaoli, Simona, Donfrancesco, Chiara, Kromhout, Daan, Price, Jackie F, Peters, Annette, Meade, Tom W, Casiglia, Edoardo, Lawlor, Debbie A, Gallacher, John, Nagel, Dorothea, Franco, Oscar H, Assmann, Gerd, Dagenais, Gilles R, Jukema, J. Wouter, Sundström, Johan, Woodward, Mark, Brunner, Eric J, Khaw, Kay-Tee, Wareham, Nicholas J, Whitsel, Eric A, Njølstad, Inger, Hedblad, Bo, Wassertheil-Smoller, Sylvia, Engström, Gunnar, Rosamond, Wayne D, Selvin, Elizabeth, Sattar, Naveed, Thompson, Simon G, Danesh, John
Published in JAMA : the journal of the American Medical Association

Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT tria...

by Holtkamp, Frank A, de Zeeuw, Dick, de Graeff, Pieter A, Laverman, Gozewijn D, Berl, Tom, Remuzzi, Giuseppe, Packham, David, Lewis, Julia B, Parving, Hans-Henrik, Lambers Heerspink, Hiddo J
Published in European heart journal

Association Between Depressive Symptoms and Incident Cardiovascular Diseases

by Harshfield, Eric L, Pennells, Lisa, Schwartz, Joseph E, Willeit, Peter, Kaptoge, Stephen, Bell, Steven, Shaffer, Jonathan A, Bolton, Thomas, Spackman, Sarah, Wassertheil-Smoller, Sylvia, Kee, Frank, Amouyel, Philippe, Shea, Steven J, Kuller, Lewis H, Kauhanen, Jussi, van Zutphen, E. M, Blazer, Dan G, Krumholz, Harlan, Nietert, Paul J, Kromhout, Daan, Laughlin, Gail, Berkman, Lisa, Wallace, Robert B, Simons, Leon A, Dennison, Elaine M, Barr, Elizabeth L. M, Meyer, Haakon E, Wood, Angela M, Danesh, John, Di Angelantonio, Emanuele, Davidson, Karina W
Published in JAMA : the journal of the American Medical Association