Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits by Southam, Lorraine, Gilly, Arthur, Süveges, Dániel, Farmaki, Aliki-Eleni, Schwartzentruber, Jeremy, Tachmazidou, Ioanna, Matchan, Angela, Rayner, Nigel W, Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria

Get full text

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates by Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R S, Xifara, Dionysia K, Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W, Chen, Yuan, Pollin, Toni I, O'Connell, Jeffrey R, Yerges-Armstrong, Laura M, Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria

Get full text

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven by Rantalainen, Mattias, Herrera, Blanca M, Nicholson, George, Bowden, Rory, Wills, Quin F, Min, Josine L, Neville, Matt J, Barrett, Amy, Allen, Maxine, Rayner, Nigel W, Fleckner, Jan, McCarthy, Mark I, Zondervan, Krina T, Karpe, Fredrik, Holmes, Chris C, Lindgren, Cecilia M

Get full text

THOC5: a novel gene involved in HDL-cholesterol metabolism[S] by Keller, Maria, Schleinitz, Dorit, Förster, Julia, Tönjes, Anke, Böttcher, Yvonne, Fischer-Rosinsky, Antje, Breitfeld, Jana, Weidle, Kerstin, Rayner, Nigel W., Burkhardt, Ralph, Enigk, Beate, Müller, Ines, Halbritter, Jan, Koriath, Moritz, Pfeiffer, Andreas, Krohn, Knut, Groop, Leif, Spranger, Joachim, Stumvoll, Michael, Kovacs, Peter

Get full text

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs by Tönjes, Anke, Koriath, Moritz, Schleinitz, Dorit, Dietrich, Kerstin, Böttcher, Yvonne, Rayner, Nigel W., Almgren, Peter, Enigk, Beate, Richter, Olaf, Rohm, Silvio, Fischer-Rosinsky, Antje, Pfeiffer, Andreas, Hoffmann, Katrin, Krohn, Knut, Aust, Gabriela, Spranger, Joachim, Groop, Leif, Blüher, Matthias, Kovacs, Peter, Stumvoll, Michael

Get full text

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study by Winkler, Thomas W, Feitosa, Mary F, Esko, Tõnu, Kilpeläinen, Tuomas O, Rüeger, Sina, Ferreira, Teresa, Absher, Devin, Bis, Joshua C, Fischer, Krista, Galesloot, Tessel E, Goel, Anuj, Gustafsson, Stefan, Haitjema, Saskia, Lahti, Jari, McKnight, Barbara, Monda, Keri L, Montasser, May E, Ryan, Kathy A, Scharnagl, Hubert, Sung, Yun Ju, van Setten, Jessica, van Vliet-Ostaptchouk, Jana V, Verweij, Niek, Zhao, Jing Hua, Andersson, Ehm A, Baldassarre, Damiano, Barlassina, Cristina, Campbell, Harry, Chen, Yii-Der Ida, Chines, Peter S, Claudi-Boehm, Simone, de Geus, Eco J C, Eury, Elodie, Friedrich, Nele, Grallert, Harald, Ham, Annelies C, Hansen, Torben, Hattersley, Andrew T, Hernandez, Dena, Hillege, Hans, Holmen, Oddgeir, Karaleftheri, Maria, Kinnunen, Leena, Kovacs, Peter, Kratzer, Wolfgang, Kuh, Diana, Kyriakou, Theodosios, Liu, Yan-Ping, Lyssenko, Valeriya, Männistö, Satu, Montgomery, Grant W, Morris, Andrew P, Ong, Ken K, Pilia, Maria G, Sanders, Alan R, Seufferlein, Thomas, Slagboom, P Eline, Stolk, Ronald P, Tsafantakis, Emmanouil, van der Most, Peter J, Völker, Uwe, Vonk, Judith M, Wennauer, Roman, Beilby, John, Boerwinkle, Eric, Bornstein, Stefan R, Chambers, John C, Farrall, Martin, Ford, Ian, Franke, Lude, Hofman, Albert, Hu, Frank, James, Alan L, Kajantie, Eero, Kivimaki, Mika, Maerz, Winfried, Martin, Nicholas G, Laakso, Markku, Melbye, Mads, Murray, Jeffrey C, Musk, Arthur W, Nieminen, Markku S, Njølstad, Inger, Ohlsson, Claes, Oldehinkel, Albertine J, Pasterkamp, Gerard, Pedersen, Oluf, Qi, Lu, Rauramaa, Rainer, Saltevo, Juha, Snieder, Harold, Spector, Tim D, Völzke, Henry, Wareham, Nicholas J, Assimes, Themistocles L, Berndt, Sonja I, Hunter, David J, van Duijn, Cornelia M, North, Kari E, Loos, Ruth J F

Get full text

Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity by Frayling, Timothy M, Timpson, Nicholas J, Weedon, Michael N, Zeggini, Eleftheria, Freathy, Rachel M, Lindgren, Cecilia M, Perry, John R.B, Elliott, Katherine S, Lango, Hana, Rayner, Nigel W, Shields, Beverley, Harries, Lorna W, Barrett, Jeffrey C, Ellard, Sian, Groves, Christopher J, Knight, Bridget, Patch, Ann-Marie, Ness, Andrew R, Ebrahim, Shah, Lawlor, Debbie A, Ring, Susan M, Ben-Shlomo, Yoav, Jarvelin, Marjo-Riitta, Sovio, Ulla, Bennett, Amanda J, Melzer, David, Ferrucci, Luigi, Loos, Ruth J.F, Barroso, Inês, Wareham, Nicholas J, Karpe, Fredrik, Owen, Katharine R, Cardon, Lon R, Walker, Mark, Hitman, Graham A, Palmer, Colin N.A, Doney, Alex S.F, Morris, Andrew D, Smith, George Davey, Hattersley, Andrew T, McCarthy, Mark I

Get full text

Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes by Weedon, Michael N, Lindgren, Cecilia M, Timpson, Nicholas J, Freathy, Rachel M, Morris, Andrew P, Walker, Mark, Doney, Alex S.F, Clayton, David G, Craddock, Nick, Deloukas, Panos, Ouwehand, Willem H, Todd, John A, Evans, David, Leung, Hin-Tak, Attwood, Antony P, Boorman, James P, Everson, Ursula, Knight, Alexandra S, Stevens, Helen E, Walters, Graham R, Walker, Neil M, Winzer, Thilo, Ring, Susan M, Strachan, David P, Pembrey, Marcus, Fraser, Christine, Jones, Ian R, Kirov, George, Williamson, Richard, Young, Allan H, Ferrier, I. Nicol, Iles, Mark M, Maqbool, Azhar, Hall, Alistair S, Braund, Peter S, Stevens, Suzanne, Thompson, John R, Bredin, Francesca, Lees, Charles W, Forbes, Alastair, Lewis, Cathryn M, Prescott, Natalie J, Todhunter, Catherine E, Ahmad, Tariq, Cummings, Fraser R, Jewell, Derek P, Webster, John, Connell, John, Dominiczak, Anna, Gungadoo, Johannie, Lee, Kate L, Munroe, Patricia B, Onipinla, Abiodun, Caulfield, Mark, Farrall, Martin, Potter, Catherine, Silman, Alan J, Worthington, Jane, Newport, Melanie, Sirugo, Giorgio, Lyons, Emily, Farrar, Claire, Brown, Matthew A, Simmonds, Matthew J, Gough, Stephen C.L, Ban, Maria, Goris, An, Compston, Alastair, Hunt, Sarah E, Inouye, Michael, McGinnis, Ralph, Widden, Claire, Su, Zhan, Teo, Yik Ying, Ouwehand, Nilesh J, Samani, Michael R, Ardern-Jones, A, Brice, G, Castle, B, Donaldson, A, Eeles, R, Goodman, S, Gray, J, Greenhalgh, L, Hodgson, S.V, Izatt, L, Jeffers, L, Locke, I, Longmuir, M, Mackay, J, Magee, A, Miedzybrodzka, Z, Paterson, J, Porteous, M, Rowe, S, Shanley, S, Saggar, A, Side, L, Steel, M, Thomas, M

Get full text

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups by Scherag, André, Dina, Christian, Hinney, Anke, Vatin, Vincent, Scherag, Susann, Vogel, Carla I G, Müller, Timo D, Grallert, Harald, Wichmann, H-Erich, Balkau, Beverley, Heude, Barbara, Jarvelin, Marjo-Riitta, Hartikainen, Anna-Liisa, Levy-Marchal, Claire, Weill, Jacques, Delplanque, Jérôme, Körner, Antje, Kiess, Wieland, Kovacs, Peter, Rayner, Nigel W, Prokopenko, Inga, McCarthy, Mark I, Schäfer, Helmut, Jarick, Ivonne, Boeing, Heiner, Fisher, Eva, Reinehr, Thomas, Heinrich, Joachim, Rzehak, Peter, Berdel, Dietrich, Borte, Michael, Biebermann, Heike, Krude, Heiko, Rosskopf, Dieter, Rimmbach, Christian, Rief, Winfried, Fromme, Tobias, Klingenspor, Martin, Schürmann, Annette, Schulz, Nadja, Nöthen, Markus M, Mühleisen, Thomas W, Erbel, Raimund, Jöckel, Karl-Heinz, Moebus, Susanne, Boes, Tanja, Illig, Thomas, Froguel, Philippe, Hebebrand, Johannes, Meyre, David

Get full text

A genome-wide association search for type 2 diabetes genes in African Americans by Palmer, Nicholette D, Cooke, Jessica N, Bostrom, Meredith A, Ferrara, Assiamira, Ziegler, Julie T, Freedman, Barry I, Scott, Laura J, Morris, Andrew P, Thorleifsson, Gudmar, Ferreira, Teresa, Dupuis, Josée, Segrè, Ayellet V, van Hoek, Mandy, Bennett, Amanda J, Boström, Kristina Bengtsson, Couper, David J, Elliott, Katherine S, Elliott, Amanda L, Erdos, Michael R, Franklin, Christopher S, Ganser, Martha, Grarup, Niels, Guiducci, Candace, Kuusisto, Johanna, Lauritzen, Torsten, Lyssenko, Valeriya, Payne, Felicity, Prokopenko, Inga, Robertson, Neil R, Rocheleau, Ghislain, Roden, Michael, Saxena, Richa, Sigurdsson, Gunnar, Thorand, Barbara, Tichet, Jean, Weedon, Michael N, Hunter, David J, Hveem, Kristian, Pramstaller, Peter P, Sijbrands, Eric, Walker, Mark, Wareham, Nicholas J, Hattersley, Andrew T, Hu, Frank B, Pedersen, Oluf, Thorsteinsdottir, Unnur, Wilson, James F, van Duijn, Cornelia M, Altshuler, David, McCarthy, Mark I, Elliott, Paul, Dehghan, Abbas, Lajunen, Taina, Kanoni, Stavroula, Zabena, Carina, O'Connell, Jeffrey, Luan, Jian'an, Roccasecca, Rosa Maria, Bochud, Murielle, Clarke, Robert, Coin, Lachlan J M, Cooper, Matthew N, Crisponi, Laura, Frants, Rune, Galan, Pilar, Graessler, Jürgen, Grundy, Scott, Gwilliam, Rhian, Hartikainen, Anna-Liisa, Hercberg, Serge, Hicks, Andrew A, Hui, Jennie, Kovacs, Peter, Manning, Alisa K, McAteer, Jarred B, Melzer, David, Meyre, David, Naitza, Silvia, Orrù, Marco, Pattaro, Cristian, Peden, John F, Pichler, Irene, Psaty, Bruce M, Rayner, Nigel W, van Dijk, Ko Willems, Waeber, Gérard, Yarnell, John W G, Zethelius, Björn, Loos, Ruth J F, Smith, George Davey, Karpe, Fredrik, Serrano-Ríos, Manuel, Ebrahim, Shah, Pramstaller, Peter Paul, Wright, Alan F, Stumvoll, Michael, Hamsten, Anders, Buchanan, Thomas A, Peltonen, Leena, Mooser, Vincent

Get full text

Analysis with the exome array identifies multiple new independent variants in lipid loci by Kanoni, Stavroula, Masca, Nicholas G D, Stirrups, Kathleen E, Varga, Tibor V, Warren, Helen R, Scott, Robert A, Southam, Lorraine, Zhang, Weihua, Yaghootkar, Hanieh, Müller-Nurasyid, Martina, Couto Alves, Alexessander, Strawbridge, Rona J, Lataniotis, Lazaros, An Hashim, Nikman, Besse, Céline, Boland, Anne, Braund, Peter S, Connell, John M, Dominiczak, Anna, Farmaki, Aliki-Eleni, Franks, Stephen, Grallert, Harald, Jansson, Jan-Håkan, Karaleftheri, Maria, Keinänen-Kiukaanniemi, Sirkka, Matchan, Angela, Pasko, Dorota, Peters, Annette, Poulter, Neil, Rayner, Nigel W, Renström, Frida, Rolandsson, Olov, Sabater-Lleal, Maria, Sennblad, Bengt, Sever, Peter, Shields, Denis, Silveira, Angela, Stanton, Alice V, Strauch, Konstantin, Tomaszewski, Maciej, Tsafantakis, Emmanouil, Waldenberger, Melanie, Blakemore, Alexandra I F, Dedoussis, George, Escher, Stefan A, Kooner, Jaspal S, McCarthy, Mark I, Palmer, Colin N A, Hamsten, Anders, Caulfield, Mark J, Frayling, Timothy M, Tobin, Martin D, Jarvelin, Marjo-Riitta, Zeggini, Eleftheria, Gieger, Christian, Chambers, John C, Wareham, Nick J, Munroe, Patricia B, Franks, Paul W, Samani, Nilesh J, Deloukas, Panos

Get full text

Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals by Kilpeläinen, Tuomas O, den Hoed, Marcel, Ong, Ken K, Grøntved, Anders, Brage, Soren, Consortium, Early Growth Genetics, Jameson, Karen, Cooper, Cyrus, Khaw, Kay-Tee, Ekelund, Ulf, Wareham, Nicholas J, Loos, Ruth JF

Get full text

Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease by Huertas-Vazquez, Adriana, Nelson, Christopher P, Guo, Xiuqing, Reinier, Kyndaron, Uy-Evanado, Audrey, Teodorescu, Carmen, Ayala, Jo, Jerger, Katherine, Chugh, Harpriya, Braund, Peter S, Deloukas, Panos, Hall, Alistair S, Balmforth, Anthony J, Jones, Michelle, Taylor, Kent D, Pulit, Sara L, Newton-Cheh, Christopher, Gunson, Karen, Jui, Jonathan, Rotter, Jerome I, Albert, Christine M, Samani, Nilesh J, Chugh, Sumeet S

Get full text