Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases

by Handley, Renee R., Reid, Suzanne J., Brauning, Rudiger, Maclean, Paul, Mears, Emily R., Fourie, Imche, Patassini, Stefano, Cooper, Garth J. S., Rudiger, Skye R., McLaughlan, Clive J., Verma, Paul J., Gusella, James F., MacDonald, Marcy E., Waldvogel, Henry J., Bawden, C. Simon, Faull, Richard L. M., Snell, Russell G.
Published in Proceedings of the National Academy of Sciences - PNAS

Failed Retrograde Transport of NGF in a Mouse Model of Down's Syndrome: Reversal of Cholinergic Neurodegenerative Phenotypes Following NGF Infusion

by Cooper, Jonathan D., Salehi, Ahmad, Delcroix, Jean-Dominique, Howe, Charles L., Belichenko, Pavel V., Chua-Couzens, Jane, Kilbridge, Joshua F., Carlson, Elaine J., Epstein, Charles J., Mobley, William C.
Published in Proceedings of the National Academy of Sciences - PNAS

Cardiovascular fitness is associated with cognition in young adulthood

by Åberg, Maria A.I, Pedersen, Nancy L, Torén, Kjell, Svartengren, Magnus, Bäckstrand, Björn, Johnsson, Tommy, Cooper-Kuhn, Christiana M, Åberg, N. David, Nilsson, Michael, Kuhn, H. Georg
Published in Proceedings of the National Academy of Sciences - PNAS

Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis

by Dodge, James C, Christopher M. Treleaven, Joshua Pacheco, Samantha Cooper, Channa Bao, Marissa Abraham, Mandy Cromwell, S. Pablo Sardi, Wei-Lien Chuang, Richard L. Sidman, Seng H. Cheng, Lamya S. Shihabuddin
Published in Proceedings of the National Academy of Sciences - PNAS

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

by Wang, Ying, O'Connell, Jeffrey R, McArdle, Patrick F, Wade, James B, Dorff, Sarah E, Shah, Sanjiv J, Shi, Xiaolian, Pan, Lin, Rampersaud, Evadnie, Shen, Haiqing, Kim, James D, Subramanya, Arohan R, Steinle, Nanette I, Parsa, Afshin, Ober, Carole C, Welling, Paul A, Chakravarti, Aravinda, Weder, Alan B, Cooper, Richard S, Mitchell, Braxton D, Shuldiner, Alan R, Chang, Yen-Pei C
Published in Proceedings of the National Academy of Sciences - PNAS

Direct measurements of meltwater runoff on the Greenland ice sheet surface

by Smith, Laurence C., Yang, Kang, Pitcher, Lincoln H, Overstreet, Brandon T., Chu, Vena W., Rennermalm, Åsa K., Ryan, Jonathan C., Cooper, Matthew G., Gleason, Colin J., Tedesco, Marco, Jeyaratnam, Jeyavinoth, van As, Dirk, van den Broeke, Michiel R., van de Berg, Willem Jan, Noël, Brice, Langen, Peter L., Cullather, Richard I., Zhao, Bin, Willis, Michael J., Hubbard, Alun, Box, Jason E., Jenner, Brittany A., Behar, Alberto E.
Published in Proceedings of the National Academy of Sciences - PNAS

Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection

by Whelan, Fiona, Lafita, Aleix, Griffiths, Samuel C., Cooper, Rachael E. M., Whittingham, Jean L., Turkenburg, Johan P., Manfield, Iain W., St. John, Alexander N., Paci, Emanuele, Bateman, Alex, Potts, Jennifer R.
Published in Proceedings of the National Academy of Sciences - PNAS

The problem with delineating narrow criteria for citizen science

by Auerbach, Jeremy, Barthelmess, Erika L., Cavalier, Darlene, Cooper, Caren B., Fenyk, Heather, Haklay, Mordechai, Hulbert, Joseph M., Kyba, Christopher C. M., Larson, Lincoln R., Lewandowski, Eva, Shanley, Lea
Published in Proceedings of the National Academy of Sciences - PNAS

Genome-wide detection of human variants that disrupt intronic branchpoints

by Zhang, Peng, Philippot, Quentin, Ren, Weicheng, Lei, Wei-Te, Li, Juan, Stenson, Peter D, Palacín, Pere Soler, Colobran, Roger, Boisson, Bertrand, Zhang, Shen-Ying, Puel, Anne, Pan-Hammarström, Qiang, Zhang, Qian, Cooper, David N, Abel, Laurent, Casanova, Jean-Laurent
Published in Proceedings of the National Academy of Sciences - PNAS

Evidence for Protein X Binding to a Discontinuous Epitope on the Cellular Prion Protein during Scrapie Prion Propagation

by Kaneko, Kiyotoshi, Zulianello, Laurence, Scott, Michael, Cooper, Carol M., Wallace, Andrew C., James, Thomas L., Cohen, Fred E., Prusiner, Stanley B.
Published in Proceedings of the National Academy of Sciences - PNAS

A Peroxisome Proliferator-Activated Receptor γ Ligand Inhibits Adipocyte Differentiation

by Oberfield, Jennifer L., Collins, Jon L., Holmes, Christopher P., Goreham, Donna M., Cooper, Joel P., Cobb, Jeffery E., Lenhard, James M., Hull-Ryde, Emily A., Mohr, Christopher P., Blanchard, Steven G., Parks, Derek J., Moore, Linda B., Lehmann, Jürgen M., Plunket, Kelli, Miller, Ann B., Milburn, Michael V., Kliewer, Steven A., Willson, Timothy M.
Published in Proceedings of the National Academy of Sciences - PNAS

Nitrous oxide emission from denitrification in stream and river networks

by Beaulieu, Jake J, Tank, Jennifer L, Hamilton, Stephen K, Wollheim, Wilfred M, Hall, Robert O. Jr, Mulholland, Patrick J, Peterson, Bruce J, Ashkenas, Linda R, Cooper, Lee W, Dahm, Clifford N, Dodds, Walter K, Grimm, Nancy B, Johnson, Sherri L, McDowell, William H, Poole, Geoffrey C, Valett, H. Maurice, Arango, Clay P, Bernot, Melody J, Burgin, Amy J, Crenshaw, Chelsea L, Helton, Ashley M, Johnson, Laura T, O'Brien, Jonathan M, Potter, Jody D, Sheibley, Richard W, Sobota, Daniel J, Thomas, Suzanne M
Published in Proceedings of the National Academy of Sciences - PNAS

Designing heterotropically activated allosteric conformational switches using supercharging

by Schnatz, Peter J., Brisendine, Joseph M., Laing, Craig C., Everson, Bernard H., French, Cooper A., Molinaro, Paul M., Koder, Ronald L.
Published in Proceedings of the National Academy of Sciences - PNAS

Identification of the Antivasopermeability Effect of Pigment Epithelium-Derived Factor and Its Active Site

by Liu, Hua, Ren, Jian-Guo, Cooper, William L., Hawkins, Charles E., Cowan, Mitra R., Tong, Patrick Y., Nathans, Jeremy
Published in Proceedings of the National Academy of Sciences - PNAS

Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons

by Cao, Jun-Li, Vialou, Vincent F., Lobo, Mary Kay, Robison, Alfred J., Neve, Rachael L., Cooper, Donald C., Nestler, Eric J., Han, Ming-Hu
Published in Proceedings of the National Academy of Sciences - PNAS

Classroom sound can be used to classify teaching practices in college science courses

by Owens, Melinda T., Seidel, Shannon B., Wong, Mike, Bejines, Travis E., Lietz, Susanne, Perez, Joseph R., Sit, Shangheng, Subedar, Zahur-Saleh, Acker, Gigi N., Akana, Susan F., Balukjian, Brad, Benton, Hilary P., Blair, J. R., Boaz, Segal M., Boyer, Katharyn E., Bram, Jason B., Burrus, Laura W., Byrd, Dana T., Caporale, Natalia, Carpenter, Edward J., Chan, Yee-Hung Mark, Chen, Lily, Chovnick, Amy, Chu, Diana S., Clarkson, Bryan K., Cooper, Sara E., Creech, Catherine, Crow, Karen D., de la Torre, José R., Denetclaw, Wilfred F., Duncan, Kathleen E., Edwards, Amy S., Erickson, Karen L., Fuse, Megumi, Gorga, Joseph J., Govindan, Brinda, Green, L. Jeanette, Hankamp, Paul Z., Harris, Holly E., He, Zheng-Hui, Ingalls, Stephen, Ingmire, Peter D., Jacobs, J. Rebecca, Kamakea, Mark, Kimpo, Rhea R., Knight, Jonathan D., Krause, Sara K., Krueger, Lori E., Light, Terrye L., Lund, Lance, Márquez-Magaña, Leticia M., McCarthy, Briana K., McPheron, Linda J., Miller-Sims, Vanessa C., Moffatt, Christopher A., Muick, Pamela C., Nagami, Paul H., Nusse, Gloria L., Okimura, Kristine M., Pasion, Sally G., Patterson, Robert, Pennings, Pleuni S., Riggs, Blake, Romeo, Joseph, Roy, Scott W., Russo-Tait, Tatiane, Schultheis, Lisa M., Sengupta, Lakshmikanta, Small, Rachel, Spicer, Greg S., Stillman, Jonathon H., Swei, Andrea, Wade, Jennifer M., Waters, Steven B., Weinstein, Steven L., Willsie, Julia K., Wright, Diana W., Harrison, Colin D., Kelley, Loretta A., Trujillo, Gloriana, Domingo, Carmen R., Schinske, Jeffrey N., Tanner, Kimberly D.
Published in Proceedings of the National Academy of Sciences - PNAS

Competing English, Spanish, and French alabaster trade in Europe over five centuries as evidenced by isotope fingerprinting

by Kloppmann, W., Leroux, L., Bromblet, P., Le Pogam, P.-Y., Cooper, A. H., Worley, N., Guerrot, C., Montech, A. T., Gallas, A. M., Aillaud, R.
Published in Proceedings of the National Academy of Sciences - PNAS

Resolving the evolution of extant and extinct ruminants with high-throughput phylogenomics

by Decker, Jared E, Pires, J. Chris, Conant, Gavin C, McKay, Stephanie D, Heaton, Michael P, Chen, Kefei, Cooper, Alan, Vilkki, Johanna, Seabury, Christopher M, Caetano, Alexandre R, Johnson, Gary S, Brenneman, Rick A, Hanotte, Olivier, Eggert, Lori S, Wiener, Pamela, Kim, Jong-Joo, Kim, Kwan Suk, Sonstegard, Tad S, Van Tassell, Curt P, Neibergs, Holly L, McEwan, John C, Brauning, Rudiger, Coutinho, Luiz L, Babar, Masroor E, Wilson, Gregory A, McClure, Matthew C, Rolf, Megan M, Kim, JaeWoo, Schnabel, Robert D, Taylor, Jeremy F
Published in Proceedings of the National Academy of Sciences - PNAS

A Biophysical Model of Bidirectional Synaptic Plasticity: Dependence on AMPA and NMDA Receptors

by Castellani, Gastone C., Quinlan, Elizabeth M., Cooper, Leon N, Shouval, Harel Z.
Published in Proceedings of the National Academy of Sciences - PNAS

Specific hypomethylation programs underpin B cell activation in early multiple sclerosis

by Ma, Qin, Caillier, Stacy J, Muzic, Shaun, Wilson, Michael R, Henry, Roland G, Cree, Bruce A C, Hauser, Stephen L, Didonna, Alessandro, Oksenberg, Jorge R
Published in Proceedings of the National Academy of Sciences - PNAS