Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

by Papadimitriou, Nikos, Dimou, Niki, Tsilidis, Konstantinos K, Banbury, Barbara, Martin, Richard M, Lewis, Sarah J, Kazmi, Nabila, Robinson, Timothy M, Albanes, Demetrius, Aleksandrova, Krasimira, Berndt, Sonja I, Timothy Bishop, D, Brenner, Hermann, Buchanan, Daniel D, Bueno-de-Mesquita, Bas, Campbell, Peter T, Castellví-Bel, Sergi, Chan, Andrew T, Chang-Claude, Jenny, Ellingjord-Dale, Merete, Figueiredo, Jane C, Gallinger, Steven J, Giles, Graham G, Giovannucci, Edward, Gruber, Stephen B, Gsur, Andrea, Hampe, Jochen, Hampel, Heather, Harlid, Sophia, Harrison, Tabitha A, Hoffmeister, Michael, Hopper, John L, Hsu, Li, María Huerta, José, Huyghe, Jeroen R, Jenkins, Mark A, Keku, Temitope O, Kühn, Tilman, La Vecchia, Carlo, Le Marchand, Loic, Li, Christopher I, Li, Li, Lindblom, Annika, Lindor, Noralane M, Lynch, Brigid, Markowitz, Sanford D, Masala, Giovanna, May, Anne M, Milne, Roger, Monninkhof, Evelyn, Moreno, Lorena, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Perduca, Vittorio, Pharoah, Paul D P, Platz, Elizabeth A, Potter, John D, Rennert, Gad, Riboli, Elio, Sánchez, Maria-Jose, Schmit, Stephanie L, Schoen, Robert E, Severi, Gianluca, Sieri, Sabina, Slattery, Martha L, Song, Mingyang, Tangen, Catherine M, Thibodeau, Stephen N, Travis, Ruth C, Trichopoulou, Antonia, Ulrich, Cornelia M, van Duijnhoven, Franzel J B, Van Guelpen, Bethany, Vodicka, Pavel, White, Emily, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Peters, Ulrike, Gunter, Marc J, Murphy, Neil
Published in Nature communications

The biosecurity benefits of genetic engineering attribution

by Lewis, Gregory, Jordan, Jacob L, Relman, David A, Koblentz, Gregory D, Leung, Jade, Dafoe, Allan, Nelson, Cassidy, Epstein, Gerald L, Katz, Rebecca, Montague, Michael, Alley, Ethan C, Filone, Claire Marie, Luby, Stephen, Church, George M, Millett, Piers, Esvelt, Kevin M, Cameron, Elizabeth E, Inglesby, Thomas V
Published in Nature communications

The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments

by Grieshaber-Bouyer, Ricardo, Radtke, Felix A, Cunin, Pierre, Stifano, Giuseppina, Levescot, Anaïs, Vijaykumar, Brinda, Nelson-Maney, Nathan, Blaustein, Rachel B, Monach, Paul A, Nigrovic, Peter A
Published in Nature communications

Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment

by Sun, Hua, Cao, Song, Mashl, R Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C, Davies, Sherri R, Bailey, Matthew H, Primeau, Tina M, Hoog, Jeremy, Mudd, Jacqueline L, Dean, 2nd, Dennis A, Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A, Jayasinghe, Reyka G, Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V, Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A, Ma, Cynthia X, Aft, Rebecca, Fuh, Katherine C, Schwarz, Julie K, Zevallos, Jose P, Puram, Sidharth V, Dipersio, John F, Davis-Dusenbery, Brandi, Ellis, Matthew J, Lewis, Michael T, Davies, Michael A, Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A, Welm, Alana L, Welm, Bryan E, Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C, Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H, Moscow, Jeffrey A, Evrard, Yvonne A, Chuang, Jeffrey H, Raphael, Benjamin J, Ding, Li
Published in Nature communications

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

by Zillikens, M Carola, Stolk, Lisette, Livshits, Gregory, Broer, Linda, Johnson, Toby, Koller, Daniel L, Malkin, Ida, Ried, Janina S, Smith, Albert V, Thorleifsson, Gudmar, Vandenput, Liesbeth, Zhang, Weihua, Aghdassi, Ali, Baier, Leslie J, Biffar, Rainer, Bochud, Murielle, Boehnke, Michael, Cauley, Jane A, Chen, Zhao, Cho, Nam H, Jin Choi, Hyung, Claussnitzer, Melina, Demuth, Ilja, Erdos, Mike, Eriksson, Johan G, Estrada, Karol, Evans, Daniel S, Feitosa, Mary F, Fu, Mao, Garcia, Melissa, Glazer, Nicole L, Grallert, Harald, Grewal, Jagvir, Hofman, Albert, Hoffman, Eric P, Hsueh, Wen-Chi, Hubbard, Alan, Husted, Lise B, Illig, Thomas, Ingelsson, Erik, Ittermann, Till, Jordan, Joanne M, Kilpeläinen, Tuomas O, Kraus, William E, Kritchevsky, Stephen, Kuulasmaa, Teemu, Lee, Jong-Young, Lerch, Markus M, Lindgren, Cecilia, Liu, Tian, Liu, Youfang, Ljunggren, Östen, Luben, Robert N, Maixner, William, McGuigan, Fiona E, Mellström, Dan, Mitchell, Braxton D, Mosekilde, Leif, Newman, Anne, Nielson, Carrie M, O'Connell, Jeffrey R, Perola, Markus, Polasek, Ozren, Räikkönen, Katri, Ripatti, Samuli, Robbins, John A, Rotter, Jerome I, Rudan, Igor, Salomaa, Veikko, Satterfield, Suzanne, Schipf, Sabine, Scott, Laura, Shen, Jian, Smith, Shad, Steinhagen-Thiessen, Elisabeth, Styrkarsdottir, Unnur, Swart, Karin M A, Tan, Sian-Tsung, Tarnopolsky, Mark A, van Schoor, Natasja M, Verma, Arjun, Vollenweider, Peter, Völzke, Henry, Wactawski-Wende, Jean, Weedon, Michael N, Welch, Ryan, Wichmann, H-Erich, Wright, Nicole C, Xie, Weijia, Zhou, Yanhua, Chambers, John C, Döring, Angela, van Duijn, Cornelia M, Kooner, Jaspal S, Stefansson, Kari, Uitterlinden, André G, Wareham, Nicholas J, Waterworth, Dawn, Loos, Ruth J F, Harris, Tamara B
Published in Nature communications

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

by Bolaender, Alexander, Zatorska, Danuta, He, Huazhong, Joshi, Suhasini, Sharma, Sahil, Digwal, Chander S., Patel, Hardik J., Sun, Weilin, Imber, Brandon S., Ochiana, Stefan O., Patel, Maulik R., Shrestha, Liza, Shah, Smit. K., Wang, Shuo, Karimov, Rashad, Tao, Hui, Patel, Pallav D., Martin, Ananda Rodilla, Yan, Pengrong, Panchal, Palak, Almodovar, Justina, Corben, Adriana, Rimner, Andreas, Ginsberg, Stephen D., Lyashchenko, Serge, Burnazi, Eva, Ku, Anson, Kalidindi, Teja, Lee, Sang Gyu, Grkovski, Milan, Beattie, Bradley J., Zanzonico, Pat, Lewis, Jason S., Larson, Steve, Rodina, Anna, Pillarsetty, Nagavarakishore, Tabar, Viviane, Dunphy, Mark P., Taldone, Tony, Shimizu, Fumiko, Chiosis, Gabriela
Published in Nature communications

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

by Zekavat, Seyedeh M, Ruotsalainen, Sanni, Handsaker, Robert E, Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M, Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A, Fu, Mao, Johnson, W Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S, Cupples, L Adrienne, Rotter, Jerome I, Rich, Stephen S, Post, Wendy, Mitchell, Braxton D, Correa, Adolfo, Metspalu, Andres, Wilson, James G, Salomaa, Veikko, Kellis, Manolis, Daly, Mark J, Neale, Benjamin M, McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Published in Nature communications

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma

by Mourikis, Thanos P, Benedetti, Lorena, Foxall, Elizabeth, Temelkovski, Damjan, Nulsen, Joel, Perner, Juliane, Cereda, Matteo, Lagergren, Jesper, Howell, Michael, Yau, Christopher, Fitzgerald, Rebecca C, Scaffidi, Paola, Ciccarelli, Francesca D
Published in Nature communications

Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection

by Ahuja, Sunil K, Manoharan, Muthu Saravanan, Lee, Grace C, McKinnon, Lyle R, Meunier, Justin A, Steri, Maristella, Harper, Nathan, Fiorillo, Edoardo, Smith, Alisha M, Restrepo, Marcos I, Branum, Anne P, Bottomley, Matthew J, Orrù, Valeria, Jimenez, Fabio, Carrillo, Andrew, Pandranki, Lavanya, Winter, Caitlyn A, Winter, Lauryn A, Gaitan, Alvaro A, Moreira, Alvaro G, Walter, Elizabeth A, Silvestri, Guido, King, Christopher L, Zheng, Yong-Tang, Zheng, Hong-Yi, Kimani, Joshua, Blake Ball, T, Plummer, Francis A, Fowke, Keith R, Harden, Paul N, Wood, Kathryn J, Ferris, Martin T, Lund, Jennifer M, Heise, Mark T, Garrett, Nigel, Canady, Kristen R, Abdool Karim, Salim S, Little, Susan J, Gianella, Sara, Smith, Davey M, Letendre, Scott, Richman, Douglas D, Cucca, Francesco, Trinh, Hanh, Sanchez-Reilly, Sandra, Hecht, Joan M, Cadena Zuluaga, Jose A, Anzueto, Antonio, Pugh, Jacqueline A, Agan, Brian K, Root-Bernstein, Robert, Clark, Robert A, Okulicz, Jason F, He, Weijing
Published in Nature communications

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

by Matejcic, Marco, Saunders, Edward J, Dadaev, Tokhir, Brook, Mark N, Wang, Kan, Sheng, Xin, Olama, Ali Amin Al, Schumacher, Fredrick R, Ingles, Sue A, Govindasami, Koveela, Benlloch, Sara, Berndt, Sonja I, Albanes, Demetrius, Koutros, Stella, Muir, Kenneth, Stevens, Victoria L, Gapstur, Susan M, Tangen, Catherine M, Batra, Jyotsna, Clements, Judith, Gronberg, Henrik, Pashayan, Nora, Schleutker, Johanna, Wolk, Alicja, West, Catharine, Mucci, Lorelei, Kraft, Peter, Cancel-Tassin, Géraldine, Sorensen, Karina D, Maehle, Lovise, Grindedal, Eli M, Strom, Sara S, Neal, David E, Hamdy, Freddie C, Donovan, Jenny L, Travis, Ruth C, Hamilton, Robert J, Rosenstein, Barry, Lu, Yong-Jie, Giles, Graham G, Kibel, Adam S, Vega, Ana, Bensen, Jeanette T, Kogevinas, Manolis, Penney, Kathryn L, Park, Jong Y, Stanford, Janet L, Cybulski, Cezary, Nordestgaard, Børge G, Brenner, Hermann, Maier, Christiane, Kim, Jeri, Teixeira, Manuel R, Neuhausen, Susan L, De Ruyck, Kim, Razack, Azad, Newcomb, Lisa F, Lessel, Davor, Kaneva, Radka, Usmani, Nawaid, Claessens, Frank, Townsend, Paul A, Gago-Dominguez, Manuela, Roobol, Monique J, Menegaux, Florence, Khaw, Kay-Tee, Cannon-Albright, Lisa A, Pandha, Hardev, Thibodeau, Stephen N, Schaid, Daniel J, Wiklund, Fredrik, Chanock, Stephen J, Easton, Douglas F, Eeles, Rosalind A, Kote-Jarai, Zsofia, Conti, David V, Haiman, Christopher A
Published in Nature communications

Determinants of mosaic chromosomal alteration fitness

by Pershad, Yash, Mack, Taralynn, Poisner, Hannah, Jakubek, Yasminka A, Stilp, Adrienne M, Mitchell, Braxton D, Lewis, Joshua P, Boerwinkle, Eric, Loos, Ruth J F, Chami, Nathalie, Wang, Zhe, Barnes, Kathleen, Pankratz, Nathan, Fornage, Myriam, Redline, Susan, Psaty, Bruce M, Bis, Joshua C, Shojaie, Ali, Silverman, Edwin K, Cho, Michael H, Yun, Jeong H, DeMeo, Dawn, Levy, Daniel, Johnson, Andrew D, Mathias, Rasika A, Taub, Margaret A, Arnett, Donna, North, Kari E, Raffield, Laura M, Carson, April P, Doyle, Margaret F, Rich, Stephen S, Rotter, Jerome I, Guo, Xiuqing, Cox, Nancy J, Roden, Dan M, Franceschini, Nora, Desai, Pinkal, Reiner, Alex P, Auer, Paul L, Scheet, Paul A, Jaiswal, Siddhartha, Weinstock, Joshua S, Bick, Alexander G
Published in Nature communications