Futures: lost to the past

by Moore, Joseph
Published in Nature (London)

Longitudinal analyses reveal immunological misfiring in severe COVID-19

by Lucas, Carolina, Wong, Patrick, Klein, Jon, Castro, Tiago B R, Silva, Julio, Sundaram, Maria, Ellingson, Mallory K, Mao, Tianyang, Oh, Ji Eun, Israelow, Benjamin, Takahashi, Takehiro, Tokuyama, Maria, Lu, Peiwen, Venkataraman, Arvind, Park, Annsea, Mohanty, Subhasis, Wang, Haowei, Wyllie, Anne L, Vogels, Chantal B F, Earnest, Rebecca, Lapidus, Sarah, Ott, Isabel M, Moore, Adam J, Muenker, M Catherine, Fournier, John B, Campbell, Melissa, Odio, Camila D, Casanovas-Massana, Arnau, Herbst, Roy, Shaw, Albert C, Medzhitov, Ruslan, Schulz, Wade L, Grubaugh, Nathan D, Dela Cruz, Charles, Farhadian, Shelli, Ko, Albert I, Omer, Saad B, Iwasaki, Akiko
Published in Nature (London)

Sex differences in immune responses that underlie COVID-19 disease outcomes

by Takahashi, Takehiro, Ellingson, Mallory K, Wong, Patrick, Israelow, Benjamin, Lucas, Carolina, Klein, Jon, Silva, Julio, Mao, Tianyang, Oh, Ji Eun, Tokuyama, Maria, Lu, Peiwen, Venkataraman, Arvind, Park, Annsea, Liu, Feimei, Meir, Amit, Sun, Jonathan, Wang, Eric Y, Casanovas-Massana, Arnau, Wyllie, Anne L, Vogels, Chantal B F, Earnest, Rebecca, Lapidus, Sarah, Ott, Isabel M, Moore, Adam J, Shaw, Albert, Fournier, John B, Odio, Camila D, Farhadian, Shelli, Dela Cruz, Charles, Grubaugh, Nathan D, Schulz, Wade L, Ring, Aaron M, Ko, Albert I, Omer, Saad B, Iwasaki, Akiko
Published in Nature (London)

NLRX1 is a regulator of mitochondrial antiviral immunity

by Lich, John D, Accavitti-Loper, Mary A, Ting, Jenny P-Y, Sun, Lijun, Heise, Mark T, Bergstralh, Daniel T, Lei, Yu, Duncan, Joseph A, Morrison, Thomas E, Ye, Zhengmao, Zimmermann, Albert G, Madden, Victoria J, Moore, Chris B, Chen, Zhijian
Published in Nature

Diverse functional autoantibodies in patients with COVID-19

by Wang, Eric Y, Mao, Tianyang, Klein, Jon, Dai, Yile, Huck, John D, Jaycox, Jillian R, Liu, Feimei, Zhou, Ting, Israelow, Benjamin, Wong, Patrick, Coppi, Andreas, Lucas, Carolina, Silva, Julio, Oh, Ji Eun, Song, Eric, Perotti, Emily S, Zheng, Neil S, Fischer, Suzanne, Campbell, Melissa, Fournier, John B, Wyllie, Anne L, Vogels, Chantal B F, Ott, Isabel M, Kalinich, Chaney C, Petrone, Mary E, Watkins, Anne E, Dela Cruz, Charles, Farhadian, Shelli F, Schulz, Wade L, Ma, Shuangge, Grubaugh, Nathan D, Ko, Albert I, Iwasaki, Akiko, Ring, Aaron M
Published in Nature (London)

DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

by He, Yizhou Joseph, Meghani, Khyati, Caron, Marie-Christine, Yang, Chunyu, Ronato, Daryl A, Bian, Jie, Sharma, Anchal, Moore, Jessica, Niraj, Joshi, Detappe, Alexandre, Doench, John G, Legube, Gaelle, Root, David E, D'Andrea, Alan D, Drané, Pascal, De, Subhajyoti, Konstantinopoulos, Panagiotis A, Masson, Jean-Yves, Chowdhury, Dipanjan
Published in Nature (London)

A primitive Y chromosome in papaya marks incipient sex chromosome evolution

by Ming, Ray, Liu, Zhiyong, Moore, Paul H, Ma, Hao, Ackerman, Christine M, Ragiba, Makandar, Yu, Qingyi, Pearl, Heather M, Kim, Minna S, Charlton, Joseph W, Stiles, John I, Zee, Francis T, Paterson, Andrew H
Published in Nature

Functional hydrogel structures for autonomous flow control inside microfluidic channels

by Beebe, David J, Moore, Jeffrey S, Bauer, Joseph M, Yu, Qing, Liu, Robin H, Devadoss, Chelladurai, Jo, Byung-Ho
Published in Nature (London)

Mapping the human genetic architecture of COVID-19

by Niemi, Mari E. K, Karjalainen, Juha, Liao, Rachel G, Neale, Benjamin M, Daly, Mark, Ganna, Andrea
Published in Nature (London)

Expanded encyclopaedias of DNA elements in the human and mouse genomes

by Moore, Jill E, Purcaro, Michael J, Pratt, Henry E, Epstein, Charles B, Shoresh, Noam, Adrian, Jessika, Kawli, Trupti, Davis, Carrie A, Dobin, Alexander, Kaul, Rajinder, Halow, Jessica, Van Nostrand, Eric L, Freese, Peter, Gorkin, David U, Shen, Yin, He, Yupeng, Mackiewicz, Mark, Pauli-Behn, Florencia, Williams, Brian A, Mortazavi, Ali, Keller, Cheryl A, Zhang, Xiao-Ou, Elhajjajy, Shaimae I, Huey, Jack, Dickel, Diane E, Snetkova, Valentina, Wei, Xintao, Wang, Xiaofeng, Rivera-Mulia, Juan Carlos, Rozowsky, Joel, Zhang, Jing, Chhetri, Surya B, Zhang, Jialing, Victorsen, Alec, White, Kevin P, Visel, Axel, Yeo, Gene W, Burge, Christopher B, Lécuyer, Eric, Gilbert, David M, Dekker, Job, Rinn, John, Mendenhall, Eric M, Ecker, Joseph R, Kellis, Manolis, Klein, Robert J, Noble, William S, Kundaje, Anshul, Guigó, Roderic, Farnham, Peggy J, Cherry, J Michael, Myers, Richard M, Ren, Bing, Graveley, Brenton R, Gerstein, Mark B, Pennacchio, Len A, Snyder, Michael P, Bernstein, Bradley E, Wold, Barbara, Hardison, Ross C, Gingeras, Thomas R, Stamatoyannopoulos, John A, Weng, Zhiping
Published in Nature (London)

Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

by Woolf, Clifford J, Samad, Tarek A, Moore, Kimberly A, Sapirstein, Adam, Billet, Sara, Allchorne, Andrew, Poole, Stephen, Bonventre, Joseph V
Published in Nature (London)

Design of amidobenzimidazole STING receptor agonists with systemic activity

by Ramanjulu, Joshi M, Pesiridis, G Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H Christian, Muelbaier, Marcel, Schneck, Jessica L, Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L, Charnley, Adam K, Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I, Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C, Li, Yue, Klein, Michael, Hopson, Christopher B, Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A, Lian, Yiqian, Duffy, Kevin J, Adams, Jerry, Foley, Kevin P, Gough, Peter J, Marquis, Robert W, Smothers, James, Hoos, Axel, Bertin, John
Published in Nature (London)

Extensive phylogenies of human development inferred from somatic mutations

by Coorens, Tim H H, Moore, Luiza, Robinson, Philip S, Sanghvi, Rashesh, Christopher, Joseph, Hewinson, James, Przybilla, Moritz J, Lawson, Andrew R J, Spencer Chapman, Michael, Cagan, Alex, Oliver, Thomas R W, Neville, Matthew D C, Hooks, Yvette, Noorani, Ayesha, Mitchell, Thomas J, Fitzgerald, Rebecca C, Campbell, Peter J, Martincorena, Iñigo, Rahbari, Raheleh, Stratton, Michael R
Published in Nature (London)

Perspectives on ENCODE

by Snyder, Michael P, Gingeras, Thomas R, Moore, Jill E, Weng, Zhiping, Gerstein, Mark B, Ren, Bing, Hardison, Ross C, Stamatoyannopoulos, John A, Graveley, Brenton R, Feingold, Elise A, Pazin, Michael J, Pagan, Michael, Gilchrist, Daniel A, Hitz, Benjamin C, Cherry, J Michael, Bernstein, Bradley E, Mendenhall, Eric M, Zerbino, Daniel R, Frankish, Adam, Flicek, Paul, Myers, Richard M
Published in Nature (London)

Integrated genomic and molecular characterization of cervical cancer

by Saller, Charles, Tarvin, Katherine, Yau, Christina, Robertson, A. Gordon, Mungall, Karen, Lim, Lynette, Mar, Richard, Clarke, Amanda, Tam, Angela, Dhalla, Noreen, Carlsen, Rebecca, Holt, Robert A, Jones, Steven J. M, Hadjipanayis, Angela, Seidman, Jonathan, Rabeno, Brenda, Huelsenbeck-Dill, Lori, Iacocca, Mary, Petrelli, Nicholas, Adebamowo, Sally N, Adebamowo, Clement, Shelton, Candace, Crain, Daniel, Mallery, David, Curley, Erin, Gardner, Johanna, Shelton, Troy, Wu, Ye, Birrer, Michael, Miller, Christopher A, Fulton, Robert S, Appelbaum, Elizabeth L, Rader, Janet S, Behmaram, Behnaz, Bradley, William, Wrangle, John, Schultz, Nikolaus, Ladanyi, Marc, Felau, Ina, Zenklusen, Jean C, Demchok, John A, Sheth, Margi, Ferguson, Martin L, Tarnuzzer, Roy, Zhang, Jiashan, Wang, Zhining, Olaniyan, Olayinka, Sofia, Heidi J, Chen, Zhong, Saleh, Anthony D, Cheng, Hui, Parfitt, Jeremy, Albert, Monique, Sekhon, Harman, Gilbert, Sebastien, Myers, Jerome, Tucker, Kelinda, Lester, Jenny, Wan, Yunhu, Miller, Judy, Cherniack, Andrew D, Meyerson, Matthew, Voet, Doug, Kim, Jaegil, Lawrence, Michael S, Gehlenborg, Nils, Lin, Pei, Gabriel, Stacey B, Schumacher, Steven E, Leraas, Kristen M, Gastier-Foster, Julie M, Danilova, Ludmila, Salvesen, Helga B, Ju, Zhenlin, Diao, Lixia, Zhao, Hao, Ryan, Michael C, Averett Byers, Lauren, Yuan, Yuan, Bristow, Christopher A, Shaw, Kenna R. Mills, Radenbaugh, Amie, Chalise, Prabhakar, Godwin, Andrew K, Auman, J. Todd, Perou, Charles M, Veluvolu, Umadevi, Rathmell, W. Kimryn, Simons, Janae V, Mose, Lisle E, Shi, Yan, Thorne, Leigh B, Walker, Joan, Moore, Kathleen, McMeekin, Scott, Nelson, Tina, Bhargava, Rohit, Bootwalla, Moiz S, Triche, Timothy, Jr, Agnew, Kathy J
Published in Nature (London)

Frequent mutation of histone―modifying genes in non―Hodgkin lymphoma

by MORIN, Ryan D, MENDEZ-LAGO, Maria, JACKMAN, Shaun, KRZYWINSKI, Martin, SCOTT, David W, TRINH, Diane L, TAMURA-WELLS, Jessica, SA LI, FIRME, Marlo R, ROGIC, Sanja, GRIFFITH, Malachi, CHAN, Susanna, MUNGALL, Andrew J, YAKOVENKO, Oleksandr, MEYER, Irmtraud M, ZHAO, Eric Y, SMAILUS, Duane, MOKSA, Michelle, CHITTARANJAN, Suganthi, RIMSZA, Lisa, BROOKS-WILSON, Angela, SPINELLI, John J, BEN-NERIAH, Susana, GOYA, Rodrigo, MEISSNER, Barbara, WOOLCOCK, Bruce, BOYLE, Merrill, MCDONALD, Helen, TAM, Angela, YONGJUN ZHAO, DELANEY, Allen, ZENG, Thomas, TSE, Kane, BUTTERFIELD, Yaron, MUNGALL, Karen L, BIROL, Inanç, HOLT, Rob, SCHEIN, Jacqueline, HORSMAN, Douglas E, MOORE, Richard, JONES, Steven J. M, CONNORS, Joseph M, HIRST, Martin, GASCOYNE, Randy D, MARRA, Marco A, CORBETT, Richard D, JOHNSON, Nathalie A, SEVERSON, Tesa M, CHIU, Readman, FIELD, Matthew
Published in Nature (London)

Failure of human rhombic lip differentiation underlies medulloblastoma formation

by Haldipur, Parthiv, Saulnier, Olivier, Sjoboen, Alexandria H, Erickson, Anders W, Ong, Winnie, Gordon, Victor, Coudière-Morrison, Ludivine, Shokouhian, Mohammad, Suárez, Raúl A, Borlase, Stephanie, Scott, David S, Vladoiu, Maria C, Farooq, Hamza, Nakashima, Takuma, Funakoshi, Yusuke, Diaz-Mejia, J Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y, Balin, Polina, Visvanathan, Abhirami, Lee, John J Y, Ayoub, Ramy, Chen, Xin, Mungall, Karen L, Bérubé, Pierre, Wang, Yu C, Kim, Seung-Ki, Delattre, Olivier, Bourdeaut, Franck, Masliah-Planchon, Julien, Grajkowska, Wieslawa A, Dirks, Peter, Fèvre-Montange, Michelle, Jouvet, Anne, French, Pim J, Kros, Johan M, Zitterbart, Karel, Bailey, Swneke D, Eberhart, Charles G, Giannini, Caterina, Garami, Miklós, Phillips, Joanna J, Ra, Young S, de Torres, Carmen, Ng, Ho-Keung, Poon, Wai S, López-Aguilar, Enrique, Gillespie, G Yancey, Van Meter, Timothy E, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C, Cooper, Michael K, Rubin, Joshua B, Kumabe, Toshihiro, Jung, Shin, Iolascon, Achille, Ferrucci, Veronica, de Antonellis, Pasqualino, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S, Van Meir, Erwin G, Porrati, Paola, Finocchiaro, Gaetano, Massimino, Maura, Carlotti, Carlos G, Roussel, Martine F, Boop, Frederick, Chan, Jennifer A, Aldinger, Kimberly A, Thompson, Eric M, Ansari, Marc, Garre, Maria L, Eguía, Pilar, Pérezpeña, Mario, Cavalli, Florence M G, Wu, Xiaochong, Daniels, Craig, Rich, Jeremy N, Jones, Steven J M, Marra, Marco A, Reimand, Jüri, Sorensen, Poul H, Wechsler-Reya, Robert J, Weiss, William A, Pugh, Trevor J, Garzia, Livia, Stein, Lincoln D, Jabado, Nada, Malkin, David, Golden, Jeffrey A, Doble, Brad, Ramaswamy, Vijay, Millen, Kathleen J, Taylor, Michael D
Published in Nature (London)

Diverse Organic-Mineral Associations in Jezero Crater, Mars

by Sharma, Sunanda, Roppel, Ryan D., Murphy, Ashley E., Beegle, Luther W., Bhartia, Rohit, Steele, Andrew, Hollis, Joseph Razzell, Siljeström, Sandra, McCubbin, Francis M., Asher, Sanford A., Abbey, William J., Allwood, Abigail C., Berger, Eve L., Bleefeld, Benjamin L., Burton, Aaron S., Bykov, Sergei V., Cardarelli, Emily L., Conrad, Pamela G., Corpolongo, Andrea, Czaja, Andrew D., DeFlores, Lauren P., Edgett, Kenneth, Farley, Kenneth A., Fornaro, Teresa, Fox, Allison C., Fries, Marc D., Harker, David, Hickman-Lewis, Keyron, Huggett, Joshua, Imbeah, Samara, Jakubek, Ryan S., Kah, Linda C., Lee, Carina, Liu, Yang, Magee, Angela, Minitti, Michelle, Moore, Kelsey R., Pascuzzo, Alyssa, Sanchez-Vahamonde, Carolina Rodriguez, Scheller, Eva L., Shkolyar, Svetlana, Stack, Kathryn M., Steadman, Kim, Tuite, Michael, Uckert, Kyle, Werynski, Alyssa, Wiens, Roger C., Williams, Amy J., Winchell, Katherine, Kennedy, Megan R., Yanchilina, Anastasia
Published in Nature (London)

Minutes-duration optical flares with supernova luminosities

by Ho, Anna Y. Q., Perley, Daniel A., Chen, Ping, Schulze, Steve, Dhillon, Vik, Kumar, Harsh, Suresh, Aswin, Swain, Vishwajeet, Bremer, Michael, Smartt, Stephen J., Anderson, Joseph P., Anupama, G. C., Awiphan, Supachai, Barway, Sudhanshu, Bellm, Eric C., Ben-Ami, Sagi, Bhalerao, Varun, de Boer, Thomas, Brink, Thomas G., Burruss, Rick, Chandra, Poonam, Chen, Ting-Wan, Chen, Wen-Ping, Cooke, Jeff, Coughlin, Michael W., Das, Kaustav K., Drake, Andrew J., Filippenko, Alexei V., Freeburn, James, Fremling, Christoffer, Fulton, Michael D., Gal-Yam, Avishay, Galbany, Lluís, Gao, Hua, Graham, Matthew J., Gromadzki, Mariusz, Gutiérrez, Claudia P., Hinds, K-Ryan, Inserra, Cosimo, A J, Nayana, Karambelkar, Viraj, Kasliwal, Mansi M., Kulkarni, Shri, Müller-Bravo, Tomás E., Magnier, Eugene A., Mahabal, Ashish A., Moore, Thomas, Ngeow, Chow-Choong, Nicholl, Matt, Ofek, Eran O., Omand, Conor M. B., Onori, Francesca, Pan, Yen-Chen, Pessi, Priscila J., Petitpas, Glen, Polishook, David, Poshyachinda, Saran, Pursiainen, Miika, Riddle, Reed, Rodriguez, Antonio C., Rusholme, Ben, Segre, Enrico, Sharma, Yashvi, Smith, Ken W., Sollerman, Jesper, Srivastav, Shubham, Strotjohann, Nora Linn, Suhr, Mark, Svinkin, Dmitry, Wang, Yanan, Wiseman, Philip, Wold, Avery, Yang, Sheng, Yang, Yi, Yao, Yuhan, Young, David R., Zheng, WeiKang
Published in Nature (London)

Evidence for a subsurface ocean on Europa

by Carr, Michael H, Belton, Michael J. S, Chapman, Clark R, Davies, Merton E, Geissler, Paul, Greenberg, Richard, McEwen, Alfred S, Tufts, Bruce R, Greeley, Ronald, Sullivan, Robert, Head, James W, Pappalardo, Robert T, Klaasen, Kenneth P, Johnson, Torrence V, Kaufman, James, Senske, David, Moore, Jeffrey, Neukum, Gerhard, Schubert, Gerald, Burns, Joseph A, Thomas, Peter, Veverka, Joseph
Published in Nature (London)