Lung adenocarcinoma promotion by air pollutants

by Hill, William, Lim, Emilia L, Weeden, Clare E, Lee, Claudia, Augustine, Marcellus, Chen, Kezhong, Kuan, Feng-Che, Marongiu, Fabio, Evans, Jr, Edward J, Moore, David A, Rodrigues, Felipe S, Pich, Oriol, Bakker, Bjorn, Cha, Hongui, Myers, Renelle, van Maldegem, Febe, Boumelha, Jesse, Veeriah, Selvaraju, Rowan, Andrew, Naceur-Lombardelli, Cristina, Karasaki, Takahiro, Sivakumar, Monica, De, Swapnanil, Caswell, Deborah R, Nagano, Ai, Black, James R M, Martínez-Ruiz, Carlos, Ryu, Min Hyung, Huff, Ryan D, Li, Shijia, Favé, Marie-Julie, Magness, Alastair, Suárez-Bonnet, Alejandro, Priestnall, Simon L, Lüchtenborg, Margreet, Lavelle, Katrina, Pethick, Joanna, Hardy, Steven, McRonald, Fiona E, Lin, Meng-Hung, Troccoli, Clara I, Ghosh, Moumita, Miller, York E, Merrick, Daniel T, Keith, Robert L, Al Bakir, Maise, Bailey, Chris, Hill, Mark S, Saal, Lao H, Chen, Yilun, George, Anthony M, Abbosh, Christopher, Kanu, Nnennaya, Lee, Se-Hoon, McGranahan, Nicholas, Berg, Christine D, Sasieni, Peter, Houlston, Richard, Turnbull, Clare, Lam, Stephen, Awadalla, Philip, Grönroos, Eva, Downward, Julian, Jacks, Tyler, Carlsten, Christopher, Malanchi, Ilaria, Hackshaw, Allan, Litchfield, Kevin, DeGregori, James, Jamal-Hanjani, Mariam, Swanton, Charles
Published in Nature (London)

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

by Vatanen, Tommi, Franzosa, Eric A, Schwager, Randall, Tripathi, Surya, Arthur, Timothy D, Vehik, Kendra, Lernmark, Åke, Hagopian, William A, Rewers, Marian J, She, Jin-Xiong, Toppari, Jorma, Ziegler, Anette-G, Akolkar, Beena, Krischer, Jeffrey P, Stewart, Christopher J, Ajami, Nadim J, Petrosino, Joseph F, Gevers, Dirk, Lähdesmäki, Harri, Vlamakis, Hera, Huttenhower, Curtis, Xavier, Ramnik J
Published in Nature (London)

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

by Mercader, Josep M, Udler, Miriam S, Wessel, Jennifer, Teslovich, Tanya M, Caulkins, Lizz, Barajas-Olmos, Francisco, Boerwinkle, Eric, Chen, Ling, Contreras-Cubas, Cecilia, Córdova, Emilio, Correa, Adolfo, DeFronzo, Ralph A, Dolan, Lawrence, Elliott, Amanda, Floyd, James S, Garay-Sevilla, Maria Eugenia, García-Ortiz, Humberto, Heard-Costa, Nancy L, Jørgensen, Marit E, Kang, Hyun Min, Kelsey, Megan, Linneberg, Allan, Liu, Ching-Ti, Liu, Jianjun, Lyssenko, Valeriya, Marcketta, Anthony, Martínez-Hernández, Angélica, Mayer-Davis, Elizabeth, Morrison, Alanna C, Ndungu, Anne, Ng, Maggie C Y, O'Dushlaine, Colm, Post, Wendy S, Vasan, Ramachandran S, Rayner, N William, Revilla-Monsalve, Cristina, Santoro, Nicola, Schurmann, Claudia, Soberón, Xavier, Strom, Tim M, Thameem, Farook, Torres, Jason M, Vujkovic, Marijana, Witte, Daniel R, Atzmon, Gil, Blangero, John, Bonnycastle, Lori L, Chan, Edmund, Cheng, Ching-Yu, Collins, Francis S, de Vries, Paul S, Glaser, Benjamin, Gonzalez, Ma Elena, Groop, Leif, Kooner, Jaspal Singh, Kwak, Soo Heon, Laakso, Markku, Nilsson, Peter, Spector, Timothy D, Tai, E Shyong, Tuomilehto, Jaakko, Wilson, James G, Burke, Brian, Carey, David J, Frossard, Philippe, Hwang, Mi Yeong, Kim, Young Jin, Kirchner, H Lester, Lee, Jong-Young, Lee, Juyoung, Loos, Ruth J F, Ma, Ronald C W, Morris, Andrew D, Palmer, Colin N A, Pankow, James, Rasheed, Asif, Saleheen, Danish, Sim, Xueling, Small, Kerrin S, Teo, Yik Ying, Haiman, Christopher, Hanis, Craig L, Dewey, Frederick E, Baras, Aris, Gieger, Christian, Meitinger, Thomas, Lange, Leslie, Pedersen, Oluf, Zeitler, Philip, Dabelea, Dana, Abecasis, Goncalo, Cox, Nancy J, Sladek, Rob, Meigs, James B, Rotter, Jerome I, Altshuler, David, Burtt, Noël P, Morris, Andrew P, Florez, Jose C, Boehnke, Michael
Published in Nature (London)

The genetic architecture of type 2 diabetes

by Teslovich, Tanya M, Mahajan, Anubha, Fontanillas, Pierre, Moutsianas, Loukas, Rivas, Manuel A, Rayner, N William, Cingolani, Pablo, Lindgren, Cecilia M, Chen, Yuhui, Huang, Jinyan, Varga, Tibor V, Green, Todd, Fingerlin, Tasha, Horikoshi, Momoko, Huh, Iksoo, Lee, Juyoung, Lee, Selyeong, Maxwell, Taylor J, Yoon, Joon, Barzilai, Nir, Han, Bok-Ghee, Kuulasmaa, Teemu, Balkau, Beverley, Giedraitis, Vilmantas, Purcell, Shaun, Kwak, Soo-Heon, Afzal, Uzma, Aguilar, David, Cheng, Ching-Yu, Palli, Domenico, Fowler, Sharon P, Freedman, Barry I, Hicks, Pamela J, Musani, Solomon K, Puppala, Sobha, Wilson, Sr, Gregory, Surdulescu, Gabriela L, Herder, Christian, Doney, Alex S F, Kinnunen, Leena, Hakaste, Liisa, Jørgensen, Marit E, Justesen, Johanne Marie, Käräjämäki, Annemari, Lannfelt, Lars, Narisu, Narisu, Melander, Olle, Milani, Lili, Neville, Matt, Qi, Qibin, Rolandsson, Olov, Stirrups, Kathleen, Blancher, Christine, Maguire, Jared, Shakir, Khalid, DePristo, Mark, de Angelis, Martin Hrabé, Jun, Goo, Murphy, Jacquelyn, Onofrio, Robert, Thorand, Barbara, Meisinger, Christa, Isomaa, Bo, Rauramaa, Rainer, Watanabe, Richard M, Bergman, Richard N, Bottinger, Erwin P, Chan, Juliana C N, Langenberg, Claudia, Jablonski, Kathleen A, Lehman, Donna M, Froguel, Philippe, Small, Kerrin S, Grallert, Harald, Glaser, Benjamin, Banks, Eric, Gieger, Christian, Illig, Thomas, Buck, Gemma, Trakalo, Joseph, Mägi, Reedik, Farjoun, Yossi, Owen, Katharine R, Gloyn, Anna L, Tuomi, Tiinamaija, Kooner, Jaspal Singh, Donnelly, Peter, Morris, Andrew D, Hattersley, Andrew T, Bowden, Donald W, Laakso, Markku, Bell, Graeme I, Duggirala, Ravindranath, McVean, Gilean, Meigs, James B, Cox, Nancy J, Mohlke, Karen L, Florez, Jose C, Morris, Andrew P, Kang, Hyun Min
Published in Nature (London)

Inhibition of LTβR signalling activates WNT-induced regeneration in lung

by Conlon, Thomas M, John-Schuster, Gerrit, Heide, Danijela, Pfister, Dominik, Lehmann, Mareike, Hu, Yan, Ertüz, Zeynep, Lopez, Martin A, Ansari, Meshal, Strunz, Maximilian, Mayr, Christoph, Angelidis, Ilias, Ciminieri, Chiara, Costa, Rita, Kohlhepp, Marlene Sophia, Guillot, Adrien, Günes, Gizem, Jeridi, Aicha, Funk, Maja C, Beroshvili, Giorgi, Prokosch, Sandra, Hetzer, Jenny, Verleden, Stijn E, Alsafadi, Hani, Lindner, Michael, Burgstaller, Gerald, Becker, Lore, Irmler, Martin, Dudek, Michael, Janzen, Jakob, Goffin, Eric, Gosens, Reinoud, Knolle, Percy, Pirotte, Bernard, Stoeger, Tobias, Beckers, Johannes, Wagner, Darcy, Singh, Indrabahadur, Theis, Fabian J, de Angelis, Martin Hrabé, O'Connor, Tracy, Tacke, Frank, Boutros, Michael, Dejardin, Emmanuel, Eickelberg, Oliver, Schiller, Herbert B, Königshoff, Melanie, Heikenwalder, Mathias, Yildirim, Ali Önder
Published in Nature (London)

Temporal development of the gut microbiome in early childhood from the TEDDY study

by Stewart, Christopher J, Ajami, Nadim J, O'Brien, Jacqueline L, Hutchinson, Diane S, Smith, Daniel P, Wong, Matthew C, Ross, Matthew C, Lloyd, Richard E, Doddapaneni, HarshaVardhan, Metcalf, Ginger A, Muzny, Donna, Gibbs, Richard A, Vatanen, Tommi, Huttenhower, Curtis, Xavier, Ramnik J, Rewers, Marian, Hagopian, William, Toppari, Jorma, Ziegler, Anette-G, She, Jin-Xiong, Akolkar, Beena, Lernmark, Ake, Hyoty, Heikki, Vehik, Kendra, Krischer, Jeffrey P, Petrosino, Joseph F
Published in Nature (London)

Stroke genetics informs drug discovery and risk prediction across ancestries

by Malik, Rainer, Hachiya, Tsuyoshi, Jürgenson, Tuuli, Namba, Shinichi, Kamanu, Frederick K, Le Grand, Quentin, He, Yunye, Georgakis, Marios K, Krebs, Kristi, Vaura, Felix C, Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Chong, Michael R, Akinyemi, Rufus, Jee, Yon Ho, Abedi, Vida, Nygaard, Marianne, Leonard, Hampton L, Knol, Maria J, Lewis, Adam J, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D, Bartz, Traci M, Bordes, Constance, Børte, Sigrid, Cain, Anael, Ridker, Paul M, Chen, Zhengming, Cole, John W, de Jager, Phil L, de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E, Geerlings, Mirjam I, Gudnason, Vilmundur, Hata, Jun, Ho, Yuk-Lam, Havulinna, Aki S, Hopewell, Jemma C, Hyacinth, Hyacinth I, Inouye, Michael, Kittner, Steven J, Kumar, Amit, Lacaze, Paul, Li, Jiang, Mitchell, Braxton D, Mosley, Thomas H, Nordestgaard, Børge G, Okada, Yukinori, Onland-Moret, N Charlotte, Ovbiagele, Bruce, Peters, Annette, Sabatine, Marc S, Saleheen, Danish, Sandset, Else Charlotte, Salomaa, Veikko, Shimizu, Atsushi, Sloane, Kelly L, Tanno, Kozo, Torres-Aguila, Nuria P, Trégouët, David-Alexandre, Trompet, Stella, Tuladhar, Anil Man, Tybjærg-Hansen, Anne, Vibo, Riina, Wiggins, Kerri L, Wilson, Peter W F, Yang, Qiong, Yoon, Kyungheon, Ninomiya, Toshiharu, Grabe, Hans J, Strbian, Daniel, Kim, Young Jin, Wassertheil-Smoller, Sylvia, Ikram, Mohammad A, Rundek, Tatjana, Lathrop, G Mark, Riaz, Moeen, Simonsick, Eleanor M, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Haeusler, Karl Georg, Heuschmann, Peter Ulrich, Longstreth, W T, Paré, Guillaume, Damrauer, Scott M, Chasman, Daniel I, Rotter, Jerome I, Anderson, Christopher D, Zwart, John-Anker, Niiranen, Teemu J, Fornage, Myriam, Liaw, Yung-Po, Fernández-Cadenas, Israel, Walters, Robin G, Ruff, Christian T, Milani, Lili
Published in Nature (London)

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

by Weinstock, Joshua S, Gopakumar, Jayakrishnan, Burugula, Bala Bharathi, Uddin, Md Mesbah, Jahn, Nikolaus, Belk, Julia A, Bouzid, Hind, Daniel, Bence, Miao, Zhuang, Ly, Nghi, Mack, Taralynn M, Luna, Sofia E, Prothro, Katherine P, Laurie, Cecelia A, Broome, Jai G, Taylor, Kent D, Guo, Xiuqing, Sinner, Moritz F, von Falkenhausen, Aenne S, Kääb, Stefan, Shuldiner, Alan R, O'Connell, Jeffrey R, Lewis, Joshua P, Boerwinkle, Eric, Barnes, Kathleen C, Chami, Nathalie, Kenny, Eimear E, Loos, Ruth J F, Fornage, Myriam, Hou, Lifang, Lloyd-Jones, Donald M, Redline, Susan, Cade, Brian E, Psaty, Bruce M, Bis, Joshua C, Brody, Jennifer A, Silverman, Edwin K, Yun, Jeong H, Qiao, Dandi, Palmer, Nicholette D, Freedman, Barry I, Bowden, Donald W, Cho, Michael H, DeMeo, Dawn L, Vasan, Ramachandran S, Yanek, Lisa R, Peyser, Patricia A, He, Jiang, Rienstra, Michiel, Van der Harst, Pim, Kaplan, Robert, Heckbert, Susan R, Smith, Nicholas L, Wiggins, Kerri L, Arnett, Donna K, Tiwari, Hemant, Cutler, Michael J, Knight, Stacey, Muhlestein, J Brent, Correa, Adolfo, Raffield, Laura M, Gao, Yan, de Andrade, Mariza, Rotter, Jerome I, Rich, Stephen S, Tracy, Russell P, Konkle, Barbara A, Johnsen, Jill M, Melander, Olle, Nilsson, Peter M, Duggirala, Ravindranath, Curran, Joanne E, Blangero, John, McGarvey, Stephen, Williams, L Keoki, Xiao, Shujie, Yang, Mao, Gu, C Charles, Lee, Wen-Jane, Marcus, Gregory M, Kane, John P, Pullinger, Clive R, Darbar, Dawood, Roden, Dan M, Albert, Christine, Kooperberg, Charles, Manson, JoAnn E, Desai, Pinkal, Johnson, Andrew D, Mathias, Rasika A, Blackwell, Thomas W, Abecasis, Goncalo R, Smith, Albert V, Kang, Hyun M, Natarajan, Pradeep, Kitzman, Jacob O, Whitsel, Eric A, Reiner, Alexander P, Bick, Alexander G, Jaiswal, Siddhartha
Published in Nature (London)

A genomic mutational constraint map using variation in 76,156 human genomes

by Chen, Siwei, Francioli, Laurent C, Goodrich, Julia K, Collins, Ryan L, Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A, Vittal, Christopher, Gauthier, Laura D, Poterba, Timothy, Wilson, Michael W, Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T, Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O'Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R, Talkowski, Michael E, Rehm, Heidi L, Daly, Mark J, Tiao, Grace, Neale, Benjamin M, MacArthur, Daniel G, Karczewski, Konrad J
Published in Nature (London)