Analysis of protein-coding genetic variation in 60,706 humans

by Lek, Monkol, Karczewski, Konrad J, Minikel, Eric V, Samocha, Kaitlin E, Banks, Eric, Fennell, Timothy, O'Donnell-Luria, Anne H, Ware, James S, Hill, Andrew J, Cummings, Beryl B, Tukiainen, Taru, Birnbaum, Daniel P, Kosmicki, Jack A, Duncan, Laramie E, Estrada, Karol, Zhao, Fengmei, Zou, James, Pierce-Hoffman, Emma, Berghout, Joanne, Cooper, David N, Deflaux, Nicole, DePristo, Mark, Do, Ron, Flannick, Jason, Fromer, Menachem, Gauthier, Laura, Goldstein, Jackie, Gupta, Namrata, Howrigan, Daniel, Kiezun, Adam, Kurki, Mitja I, Moonshine, Ami Levy, Natarajan, Pradeep, Orozco, Lorena, Peloso, Gina M, Poplin, Ryan, Rivas, Manuel A, Ruano-Rubio, Valentin, Rose, Samuel A, Ruderfer, Douglas M, Shakir, Khalid, Stenson, Peter D, Stevens, Christine, Thomas, Brett P, Tiao, Grace, Tusie-Luna, Maria T, Weisburd, Ben, Won, Hong-Hee, Yu, Dongmei, Altshuler, David M, Ardissino, Diego, Boehnke, Michael, Danesh, John, Donnelly, Stacey, Elosua, Roberto, Florez, Jose C, Gabriel, Stacey B, Getz, Gad, Glatt, Stephen J, Hultman, Christina M, Kathiresan, Sekar, Laakso, Markku, McCarroll, Steven, McCarthy, Mark I, McGovern, Dermot, McPherson, Ruth, Neale, Benjamin M, Palotie, Aarno, Purcell, Shaun M, Saleheen, Danish, Scharf, Jeremiah M, Sklar, Pamela, Sullivan, Patrick F, Tuomilehto, Jaakko, Tsuang, Ming T, Watkins, Hugh C, Wilson, James G, Daly, Mark J, MacArthur, Daniel G
Published in Nature (London)

Host genetic regulation of human gut microbial structural variation

by Zhernakova, Daria V, Wang, Daoming, Liu, Lei, Andreu-Sánchez, Sergio, Zhang, Yue, Ruiz-Moreno, Angel J, Peng, Haoran, Plomp, Niels, Del Castillo-Izquierdo, Ángela, Gacesa, Ranko, Lopera-Maya, Esteban A, Temba, Godfrey S, Kullaya, Vesla I, van Leeuwen, Sander S, Xavier, Ramnik J, de Mast, Quirijn, Joosten, Leo A B, Riksen, Niels P, Rutten, Joost H W, Netea, Mihai G, Sanna, Serena, Wijmenga, Cisca, Weersma, Rinse K, Zhernakova, Alexandra, Harmsen, Hermie J M, Fu, Jingyuan
Published in Nature (London)

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

by Purcell, Shaun M, Wray, Naomi R, Stone, Jennifer L, Visscher, Peter M, O'Donovan, Michael C, Sullivan, Patrick F, Sklar, Pamela
Published in Nature (London)

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

by Majumdar, Manas K, Glasson, Sonya S, Flannery, Carl R, Morris, Elisabeth A, Blanchet, Tracey, Askew, Roger, Peluso, Diane, Kanki, Kim, Yang, Zhiyong, Ma, Hak-Ling, Carito, Brenda, Sheppard, Barbara
Published in Nature

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

by Sebat, Jonathan, Vacic, Vladimir, McCarthy, Shane, Malhotra, Dheeraj, Murray, Fiona, Chou, Hsun-Hua, Peoples, Aine, Makarov, Vladimir, Yoon, Seungtai, Bhandari, Abhishek, Corominas, Roser, Iakoucheva, Lilia M, Krastoshevsky, Olga, Krause, Verena, Larach-Walters, Verónica, Welsh, David K, Craig, David, Kelsoe, John R, Gershon, Elliot S, Leal, Suzanne M, Aquila, Marie Dell, Morris, Derek W, Gill, Michael, Corvin, Aiden, Insel, Paul A, McClellan, Jon, King, Mary-Claire, Karayiorgou, Maria, Levy, Deborah L, DeLisi, Lynn E
Published in Nature (London)

Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast

by Reed, Steven I, Morris, May C, Kaiser, Peter, Rudyak, Stanislav, Baskerville, Chris, Watson, Mark H
Published in Nature (London)

High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome

by Denver, Dee R, Morris, Krystalynne, Lynch, Michael, Thomas, W. Kelley
Published in Nature

Mapping the human genetic architecture of COVID-19

by Niemi, Mari E. K, Karjalainen, Juha, Liao, Rachel G, Neale, Benjamin M, Daly, Mark, Ganna, Andrea
Published in Nature (London)

Whole-genome sequencing reveals host factors underlying critical COVID-19

by Kousathanas, Athanasios, Pairo-Castineira, Erola, Rawlik, Konrad, Stuckey, Alex, Odhams, Christopher A, Walker, Susan, Russell, Clark D, Malinauskas, Tomas, Wu, Yang, Millar, Jonathan, Shen, Xia, Elliott, Katherine S, Griffiths, Fiona, Oosthuyzen, Wilna, Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Maslove, David, Nichol, Alistair, Semple, Malcolm G, Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Knight, Julian, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Kosmicki, Jack A, Horowitz, Julie E, Baras, Aris, Abecasis, Goncalo R, Ferreira, Manuel A R, Justice, Anne, Mirshahi, Tooraj, Oetjens, Matthew, Rader, Daniel J, Ritchie, Marylyn D, Verma, Anurag, Fowler, Tom A, Shankar-Hari, Manu, Summers, Charlotte, Hinds, Charles, Horby, Peter, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Openshaw, Peter J M, Elliott, Paul, Walsh, Timothy, Tenesa, Albert, Fawkes, Angie, Murphy, Lee, Rowan, Kathy, Ponting, Chris P, Vitart, Veronique, Wilson, James F, Yang, Jian, Bretherick, Andrew D, Scott, Richard H, Hendry, Sara Clohisey, Moutsianas, Loukas, Law, Andy, Caulfield, Mark J, Baillie, J Kenneth
Published in Nature (London)

Genetic studies of body mass index yield new insights for obesity biology

by Berndt, Sonja I, Esko, Tonu, Fall, Tove, Gustafsson, Stefan, Workalemahu, Tsegaselassie, Smith, Jennifer A, Absher, Devin, Amin, Najaf, Deng, Guohong, Feitosa, Mary F, Gong, Jian, Pasko, Dorota, Shungin, Dmitry, Strawbridge, Rona J, Zhang, Weihua, Bellis, Claire, Berne, Christian, Böhringer, Stefan, Bonnycastle, Lori L, Boyd, Heather A, Bruinenberg, Marcel, Clarke, Robert, Delgado, Graciela, Folkersen, Lasse, Garcia, Melissa E, Grönberg, Henrik, Gusto, Gaëlle, Hassinen, Maija, Johansson, Åsa, Kinnunen, Leena, Kratzer, Wolfgang, Lichtner, Peter, Lind, Lars, Lorbeer, Roberto, Mahajan, Anubha, Menni, Cristina, Milani, Lili, Musk, Arthur W, Rettig, Rainer, Sanna, Serena, Schumacher, Fredrick R, Shi, Jianxin, Swift, Amy J, Thorand, Barbara, Waterworth, Dawn, Wright, Alan F, Zhang, Qunyuan, Choi, Murim, Dastani, Zari, Gådin, Jesper R, Handsaker, Robert E, Kubo, Michiaki, Salem, Rany M, Tanaka, Toshihiro, Bakker, Stephan J L, Bovet, Pascal, Campbell, Harry, Cesana, Giancarlo, Chakravarti, Aravinda, Chines, Peter S, Crawford, Dana C, den Ruijter, Hester M, Farrall, Martin, Ferrières, Jean, Forrester, Terrence, Hindorff, Lucia A, Humphries, Steve E, Hyppönen, Elina, Jukema, J Wouter, Kovacs, Peter, Kuusisto, Johanna, Männistö, Satu, Morris, Andrew D, Murray, Jeffrey C, Oldehinkel, Albertine J, Rioux, John D, Samani, Nilesh J, Sarzynski, Mark A, Stolk, Ronald P, Völker, Uwe, Waeber, Gérard, Bochud, Murielle, Bottinger, Erwin P, Bouchard, Claude, Froguel, Philippe, Groop, Leif C, Hamsten, Anders, Hui, Jennie, Hunter, David J, Kaplan, Robert C, Schadt, Eric E, van der Harst, Pim, Watkins, Hugh, Weir, David R, Wilson, James F, Heid, Iris M, Stefansson, Kari, Abecasis, Gonçalo R, McCarthy, Mark I, Hirschhorn, Joel N
Published in Nature (London)

Biological insights from 108 schizophrenia-associated genetic loci

by Neale, Benjamin M, Pers, Tune H, Agartz, Ingrid, Agerbo, Esben, Amin, Farooq, Bergen, Sarah E, Bigdeli, Tim B, Buckner, Randy L, Cai, Guiqing, Catts, Stanley V, Chan, Raymond C. K, Chen, Eric Y. H, Cheng, Wei, Cheung, Eric F. C, Ann Chong, Siow, Robert Cloninger, C, Cohen, Nadine, Crowley, James J, Davidson, Michael, Davis, Kenneth L, Del Favero, Jurgen, Demontis, Ditte, Dinan, Timothy, Djurovic, Srdjan, Drapeau, Elodie, Eriksson, Johan, Escott-Price, Valentina, Friedl, Marion, Fromer, Menachem, Genovese, Giulio, Georgieva, Lyudmila, Giusti-Rodriguez, Paola, Gopal, Srihari, Gratten, Jacob, Hammer, Christian, Hofman, Andrea, Hougaard, David M, Julia, Antonio, Klovins, Janis, Ausrele Kucinskiene, Zita, Hong Lee, S, Lerer, Bernard, Limborska, Svetlana, Lubinski, Jan, Macek Jr, Milan, Magnusson, Patrik K. E, Mattheisen, Manuel, McDonald, Colm, Michie, Patricia T, Milanova, Vihra, Mokrab, Younes, Muller-Myhsok, Bertram, Nenadic, Igor, Nordin, Annelie, Van Os, Jim, Endophenotypes International Consortium, Psychosis, Parkhomenko, Elena, Pejovic-Milovancevic, Milica, Pimm, Jonathan, Price, Alkes, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Roffman, Joshua L, Schubert, Christian R, Schwab, Sibylle G, Scott, Rodney J, Seidman, Larry J, Silverman, Jeremy M, Smoller, Jordan W, Steinberg, Stacy, Strengman, Eric, Strohmaier, Jana, Svrakic, Dragan M, Soderman, Erik, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Veijola, Juha, Walsh, Dermot, Weiser, Mark, Wolen, Aaron R, Zheng, Xuebin, Wray, Naomi R, Visscher, Peter M, Trust Case-Control Consortium, Wellcome, Andreassen, Ole A, Blackwood, Douglas H. R, Esko, Tonu, Gill, Michael, Jablensky, Assen V, McCarroll, Steven A, Mowry, Bryan J, Owen, Michael J, Pato, Carlos N, Posthuma, Danielle, Rujescu, Dan, Sham, Pak C, Sklar, Pamela, St Clair, David
Published in Nature (London)

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

by Hasty, Paul, Bradley, Allan, Morris, Julia H, Edmondson, Diane G, Venuti, Judith M, Olson, Eric N, Klein, William H
Published in Nature (London)

Antisense RNA inhibition of polygalacturonase gene expression in transgenic tomatoes

by Smith, C.J.S, Watson, C.F, Ray, J, Bird, C.R, Morris, P.C, Schuch, W, Grierson, D
Published in Nature (London)

Immunological unresponsiveness induced by recipient cells transfected with donor MHC genes

by Madsen, Joren C, Superina, Riccardo A, Wood, Kathryn J, Morris, Peter J
Published in Nature (London)

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

by Morris, P, Shaman, J, Attaya, M, Amaya, M, Goodman, S, Bergman, C, Monaco, J J, Mellins, E
Published in Nature (London)

Synergism of Inositol Trisphosphate and Tetrakisphosphate in Activating Ca(2plus)-Dependent K(plus) Channels

by Morris, A P, Gallacher, D V, Irvine, R F, Petersen, O H
Published in Nature (London)

Loss of integrin alphavbeta6-mediated TGF-beta activation causes Mmp12-dependent emphysema

by Morris, David G, Huang, Xiaozhu, Kaminski, Naftali, Wang, Yanli
Published in Nature (London)

Primate (eta)-Globin DNA Sequences and Man's Place among the Great Apes

by Koop, Ben F, Goodman, Morris, Xu, Peilin, Chan, Keith, Slightom, Jerry L
Published in Nature (London)