Dirichlet process mixture models to impute missing predictor data in counterfactual prediction models: an application to predict optimal type 2 diabetes therapy

by Cardoso, Pedro, Dennis, John M, Bowden, Jack, Shields, Beverley M, McKinley, Trevelyan J
Published in BMC medical informatics and decision making

Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis

by Leete, Pia, Oram, Richard A., McDonald, Timothy J., Shields, Beverley M., Ziller, Clemens, Hattersley, Andrew T., Richardson, Sarah J., Morgan, Noel G.
Published in Diabetologia

A UK nationwide prospective study of treatment change in MODY: genetic subtype and clinical characteristics predict optimal glycaemic control after discontinuing insulin and metfor...

by Shepherd, Maggie H., Shields, Beverley M., Hudson, Michelle, Pearson, Ewan R., Hyde, Christopher, Ellard, Sian, Hattersley, Andrew T., Patel, Kashyap A.
Published in Diabetologia

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

by Oram, Richard A., Jones, Angus G., Besser, Rachel E. J., Knight, Bridget A., Shields, Beverley M., Brown, Richard J., Hattersley, Andrew T., McDonald, Timothy J.
Published in Diabetologia

Recent UK type 2 diabetes treatment guidance represents a near whole population indication for SGLT2-inhibitor therapy

by Young, Katherine G, Hopkins, Rhian, Shields, Beverley M, Thomas, Nicholas J, McGovern, Andrew P, Dennis, John M
Published in Cardiovascular diabetology

The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

by Young, Katherine G., McGovern, Andrew P., Barroso, Inês, Hattersley, Andrew T., Jones, Angus G., Shields, Beverley M., Thomas, Nicholas J., Dennis, John M.
Published in Diabetologia

Comparison of causal forest and regression-based approaches to evaluate treatment effect heterogeneity: an application for type 2 diabetes precision medicine

by Venkatasubramaniam, Ashwini, Mateen, Bilal A, Shields, Beverley M, Hattersley, Andrew T, Jones, Angus G, Vollmer, Sebastian J, Dennis, John M
Published in BMC medical informatics and decision making

Correction to: The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis

by Young, Katherine G., McGovern, Andrew P., Barroso, Inês, Hattersley, Andrew T., Jones, Angus G., Shields, Beverley M., Thomas, Nicholas J., Dennis, John M.
Published in Diabetologia

HbA1c screening for the diagnosis of diabetes. Reply to Brož J, Brabec M, Krollová P et al [letter]

by Young, Katherine G., McGovern, Andrew P., Barroso, Inês, Hattersley, Andrew T., Jones, Angus G., Shields, Beverley M., Thomas, Nicholas J., Dennis, John M.
Published in Diabetologia

Choice of HbA1c threshold for identifying individuals at high risk of type 2 diabetes and implications for diabetes prevention programmes: a cohort study

by Rodgers, Lauren R, Hill, Anita V, Dennis, John M, Craig, Zoe, May, Benedict, Hattersley, Andrew T, McDonald, Timothy J, Andrews, Rob C, Jones, Angus, Shields, Beverley M
Published in BMC medicine

Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures

by Haulder, Maneka, Hughes, Alice E, Beaumont, Robin N, Knight, Bridget A, Hattersley, Andrew T, Shields, Beverley M, Freathy, Rachel M
Published in BMC pediatrics

Genetic effects on the timing of parturition and links to fetal birth weight

by Solé-Navais, Pol, Flatley, Christopher, Steinthorsdottir, Valgerdur, Vaudel, Marc, Juodakis, Julius, Chen, Jing, Laisk, Triin, LaBella, Abigail L, Westergaard, David, Bacelis, Jonas, Brumpton, Ben Michael, Skotte, Line, Borges, Maria C, Helgeland, Øyvind, Mahajan, Anubha, Wielscher, Matthias, Lin, Frederick, Briggs, Catherine, Wang, Carol A, Moen, Gunn-Helen Øiseth, Beaumont, Robin N, Bradfield, Jonathan P, Abraham, Abin, Thorleifsson, Gudmar, Gabrielsen, Maiken Elvestad, Ostrowski, Sisse R, Modzelewska, Dominika, Nøhr, Ellen Aagaard, Hypponen, Elina, Srivastava, Amit, Talbot, Octavious, Allard, Catherine, Williams, Scott M, Menon, Ramkumar, Shields, Beverley M, Sveinbjornsson, Gardar, Xu, Huan, Melbye, Mads, Lowe, William, Bouchard, Luigi, Oken, Emily, Pedersen, Ole B, Gudbjartsson, Daniel F, Erikstrup, Christian, Sørensen, Erik, Lie, Rolv T, Teramo, Kari, Hallman, Mikko, Juliusdottir, Thorhildur, Hakonarson, Hakon, Ullum, Henrik, Hattersley, Andrew T, Sletner, Line, Merialdi, Mario, Rifas-Shiman, Sheryl L, Steingrimsdottir, Thora, Scholtens, Denise, Power, Christine, West, Jane, Nyegaard, Mette, Capra, John A, Skogholt, Anne Heidi, Magnus, Per Minor, Andreassen, Ole, Thorsteinsdottir, Unnur, Grant, Struan F. A, Qvigstad, Elisabeth, Pennell, Craig E, Hivert, Marie-France, Hayes, Geoffrey M, Jarvelin, Marjo-Riitta, McCarthy, Mark I, Lawlor, Deborah A, Nielsen, Henriette S, Mägi, Reedik, Rokas, Antonis, Hveem, Kristian, Stefansson, Kari, Feenstra, Bjarke, Njølstad, Pål Rasmus, Muglia, Louis J, Freathy, Rachel M, Johansson, Stefan, Zhang, Ge, Jacobsson, Bo
Published in Nature genetics

Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes

by Cardoso, Pedro, Young, Katie G., Nair, Anand T. N., Hopkins, Rhian, McGovern, Andrew P., Haider, Eram, Karunaratne, Piyumanga, Donnelly, Louise, Mateen, Bilal A., Sattar, Naveed, Holman, Rury R., Bowden, Jack, Hattersley, Andrew T., Pearson, Ewan R., Jones, Angus G., Shields, Beverley M., McKinley, Trevelyan J., Dennis, John M.
Published in Diabetologia

Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia

by Hope, Suzy V., Knight, Bridget A., Shields, Beverley M., Hill, Anita V., Choudhary, Pratik, Strain, W. David, McDonald, Timothy J., Jones, Angus G.
Published in Diabetologia

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

by Beaumont, Robin N, Flatley, Christopher, Vaudel, Marc, Wu, Xiaoping, Chen, Jing, Moen, Gunn-Helen Øiseth, Skotte, Line, Helgeland, Øyvind, Solé-Navais, Pol, Banasik, Karina, Albiñana, Clara, Ronkainen, Justiina, Fadista, João, Stinson, Sara Elizabeth, Trajanoska, Katerina, Wang, Carol A, Westergaard, David, Srinivasan, Sundararajan, Sánchez-Soriano, Carlos, Bilbao, Jose Ramon, Allard, Catherine, Groleau, Marika, Kuulasmaa, Teemu, Leirer, Daniel J, White, Frédérique, Jacques, Pierre-Étienne, Cheng, Haoxiang, Hao, Ke, Andreassen, Ole, Åsvold, Bjørn Olav, Atalay, Mustafa, Bhatta, Laxmi, Bouchard, Luigi, Brumpton, Ben Michael, Brunak, Søren, Bybjerg-Grauholm, Jonas, Ebbing, Cathrine, Elliott, Paul, Engelbrechtsen, Line, Erikstrup, Christian, Estarlich, Marisa, Franks, Stephen, Gaillard, Romy, Geller, Frank, Grove, Jakob, Hougaard, David M, Kajantie, Eero Olavi, Morgen, Camilla S, Nøhr, Ellen Aagaard, Nyegaard, Mette, Palmer, Colin N. A, Pedersen, Ole Birger, Rivadeneira, Fernando, Sebert, Sylvain, Shields, Beverley M, Stoltenberg, Camilla, Surakka, Ida, Thørner, Lise Wegner, Ullum, Henrik, Vaarasmaki, Marja, Vilhjalmsson, Bjarni J, Willer, Cristen J, Lakka, Timo A, Gybel-Brask, Dorte, Bustamante, Mariona, Hansen, Torben, Pearson, Ewan R, Reynolds, Rebecca M, Ostrowski, Sisse R, Pennell, Craig E, Jaddoe, Vincent W. V, Felix, Janine F, Hattersley, Andrew T, Melbye, Mads, Lawlor, Deborah A, Hveem, Kristian, Werge, Thomas, Nielsen, Henriette Svarre, Magnus, Per Minor, Evans, David M, Jacobsson, Bo, Järvelin, Marjo-Riitta, Zhang, Ge, Hivert, Marie-France, Johansson, Stefan, Freathy, Rachel M, Feenstra, Bjarke, Njølstad, Pål Rasmus
Published in Nature genetics

Effect of perchlorate and thiocyanate exposure on thyroid function of pregnant women from South-West England: a cohort study

by Knight, Bridget A, Shields, Beverley M, He, Xuemei, Pearce, Elizabeth N, Braverman, Lewis E, Sturley, Rachel, Vaidya, Bijay
Published in Thyroid research

What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study

by McGovern, Andrew P, Dennis, John M, Shields, Beverley M, Hattersley, Andrew T, Pearson, Ewan R, Jones, Angus G
Published in BMC medicine

Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes

by Thomas, Nicholas J., Lynam, Anita L., Hill, Anita V., Weedon, Michael N., Shields, Beverley M., Oram, Richard A., McDonald, Timothy J., Hattersley, Andrew T., Jones, Angus G.
Published in Diabetologia

Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in...

by Lynam, Anita L, Dennis, John M, Owen, Katharine R, Oram, Richard A, Jones, Angus G, Shields, Beverley M, Ferrat, Lauric A
Published in Diagnostic and prognostic research

Towards a systematic nationwide screening strategy for MODY

by Shields, Beverley, Colclough, Kevin
Published in Diabetologia