Selection and adaptive introgression guided the complex evolutionary history of the European common bean

by Bellucci, Elisa, Benazzo, Andrea, Xu, Chunming, Bitocchi, Elena, Rodriguez, Monica, Alseekh, Saleh, Di Vittori, Valerio, Gioia, Tania, Neumann, Kerstin, Cortinovis, Gaia, Frascarelli, Giulia, Murube, Ester, Trucchi, Emiliano, Nanni, Laura, Ariani, Andrea, Logozzo, Giuseppina, Shin, Jin Hee, Liu, Chaochih, Jiang, Liang, Ferreira, Juan José, Campa, Ana, Attene, Giovanna, Morrell, Peter L, Bertorelle, Giorgio, Graner, Andreas, Gepts, Paul, Fernie, Alisdair R, Jackson, Scott A, Papa, Roberto
Published in Nature communications

Whole-genome sequencing of Oryza brachyantha reveals mechanisms underlying Oryza genome evolution

by Chen, Jinfeng, Huang, Quanfei, Gao, Dongying, Wang, Junyi, Lang, Yongshan, Liu, Tieyan, Li, Bo, Bai, Zetao, Luis Goicoechea, Jose, Liang, Chengzhi, Chen, Chengbin, Zhang, Wenli, Sun, Shouhong, Liao, Yi, Zhang, Xuemei, Yang, Lu, Song, Chengli, Wang, Meijiao, Shi, Jinfeng, Liu, Geng, Liu, Junjie, Zhou, Heling, Zhou, Weili, Yu, Qiulin, An, Na, Chen, Yan, Cai, Qingle, Wang, Bo, Liu, Binghang, Min, Jiumeng, Huang, Ying, Wu, Honglong, Li, Zhenyu, Zhang, Yong, Yin, Ye, Song, Wenqin, Jiang, Jiming, Jackson, Scott A, Wing, Rod A, Wang, Jun, Chen, Mingsheng
Published in Nature communications

Structure of the human multidrug transporter ABCG2

by Taylor, Nicholas M I, Manolaridis, Ioannis, Jackson, Scott M, Kowal, Julia, Stahlberg, Henning, Locher, Kaspar P
Published in Nature (London)

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

by Manolaridis, Ioannis, Jackson, Scott M, Taylor, Nicholas M I, Kowal, Julia, Stahlberg, Henning, Locher, Kaspar P
Published in Nature (London)

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

by Han, Kyuho, Pierce, Sarah E, Li, Amy, Spees, Kaitlyn, Anderson, Gray R, Seoane, Jose A, Lo, Yuan-Hung, Dubreuil, Michael, Olivas, Micah, Kamber, Roarke A, Wainberg, Michael, Kostyrko, Kaja, Kelly, Marcus R, Yousefi, Maryam, Simpkins, Scott W, Yao, David, Lee, Keonil, Kuo, Calvin J, Jackson, Peter K, Sweet-Cordero, Alejandro, Kundaje, Anshul, Gentles, Andrew J, Curtis, Christina, Winslow, Monte M, Bassik, Michael C
Published in Nature (London)

Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire

by Rodriguez, Oscar L, Safonova, Yana, Silver, Catherine A, Shields, Kaitlyn, Gibson, William S, Kos, Justin T, Tieri, David, Ke, Hanzhong, Jackson, Katherine J L, Boyd, Scott D, Smith, Melissa L, Marasco, Wayne A, Watson, Corey T
Published in Nature communications

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

by Lafkas, Daniel, Shelton, Amy, Chiu, Cecilia, de Leon Boenig, Gladys, Chen, Yongmei, Stawicki, Scott S, Siltanen, Christian, Reichelt, Mike, Zhou, Meijuan, Wu, Xiumin, Eastham-Anderson, Jeffrey, Moore, Heather, Roose-Girma, Meron, Chinn, Yvonne, Hang, Julie Q, Warming, Søren, Egen, Jackson, Lee, Wyne P, Austin, Cary, Wu, Yan, Payandeh, Jian, Lowe, John B, Siebel, Christian W
Published in Nature (London)

A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's disease

by Tsartsalis, Stergios, Sleven, Hannah, Fancy, Nurun, Wessely, Frank, Smith, Amy M, Willumsen, Nanet, Cheung, To Ka Dorcas, Rokicki, Michal J, Chau, Vicky, Ifie, Eseoghene, Khozoie, Combiz, Ansorge, Olaf, Yang, Xin, Jenkyns, Marion H, Davey, Karen, McGarry, Aisling, Muirhead, Robert C J, Debette, Stephanie, Jackson, Johanna S, Montagne, Axel, Owen, David R, Miners, J Scott, Love, Seth, Webber, Caleb, Cader, M Zameel, Matthews, Paul M
Published in Nature communications

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

by Taliun, Daniel, Kessler, Michael D, Carlson, Jedidiah, Taliun, Sarah A Gagliano, Kang, Hyun Min, Tian, Xiaowen, Browning, Brian L, Clarke, Wayne E, Loesch, Douglas P, Shetty, Amol C, Blackwell, Thomas W, Smith, Albert V, Liu, Xiaoming, Conomos, Matthew P, Bobo, Dean M, Aguet, François, Arking, Dan E, Aslibekyan, Stella, Auer, Paul L, Barnard, John, Barr, R Graham, Barwick, Lucas, Becker, Lewis C, Bielak, Lawrence F, Bowden, Donald W, Brody, Jennifer A, Burchard, Esteban G, Cade, Brian E, Chasman, Daniel I, Chen, Yii-Der Ida, Choi, Seung Hoan, Chung, Mina K, Correa, Adolfo, Curran, Joanne E, Custer, Brian, Daya, Michelle, DeMeo, Dawn L, Ellinor, Patrick T, Eng, Celeste, Fingerlin, Tasha, Forer, Lukas, Fullerton, Stephanie M, Germer, Soren, Gottlieb, Daniel J, Guo, Xiuqing, He, Jiang, Heckbert, Susan R, Kelly, Tanika, Kelly, Shannon, Kenny, Eimear E, Klemmer, Robert, Konkle, Barbara A, Kooperberg, Charles, Köttgen, Anna, Lasky-Su, Jessica, Levy, Daniel, Lin, Xihong, Liu, Chunyu, Lubitz, Steven A, Mak, Angel C Y, Manichaikul, Ani, Manning, Alisa K, Mathias, Rasika A, McManus, David D, Meigs, James B, Meyers, Deborah A, Montasser, May E, Montgomery, Courtney, Morrison, Alanna C, Murabito, Joanne M, Nelson, Sarah C, North, Kari E, Peloso, Gina M, Peyser, Patricia A, Post, Wendy S, Rao, D C, Redline, Susan, Roden, Dan, Sarnowski, Chloé, Schwartz, David A, Sheehan, Vivien A, Smith, Nicholas L, Smith, Jennifer A, Sotoodehnia, Nona, Tang, Weihong, Taylor, Kent D, Telen, Marilyn, Tracy, Russell P, Vasan, Ramachandran S, Viaud-Martinez, Karine A, Vrieze, Scott, Weeks, Daniel E, Weiss, Scott T, Gan, Weiniu, Nickerson, Deborah A, Browning, Sharon R, Wilson, James G, Laurie, Cathy C, Hernandez, Ryan D, Abecasis, Gonçalo R
Published in Nature (London)

Midbrain circuit regulation of individual alcohol drinking behaviors in mice

by Juarez, Barbara, Morel, Carole, Ku, Stacy M, Liu, Yutong, Zhang, Hongxing, Montgomery, Sarah, Gregoire, Hilledna, Ribeiro, Efrain, Crumiller, Marshall, Roman-Ortiz, Ciorana, Walsh, Jessica J, Jackson, Kelcy, Croote, Denise E, Zhu, Yingbo, Zhang, Song, Vendruscolo, Leandro F, Edwards, Scott, Roberts, Amanda, Hodes, Georgia E, Lu, Yongke, Calipari, Erin S, Chaudhury, Dipesh, Friedman, Allyson K, Han, Ming-Hu
Published in Nature communications

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

by Bick, Alexander G, Nandakumar, Satish K, Fulco, Charles P, Zekavat, Seyedeh M, Szeto, Mindy D, Leventhal, Matthew J, Nasser, Joseph, Chang, Kyle, Gibson, Christopher J, Lin, Amy E, Taub, Margaret A, Barnes, Kathleen C, Moscati, Arden, Psaty, Bruce M, Silverman, Edwin K, Weiss, Scott T, Palmer, Nicholette D, Vasan, Ramachandran S, Burchard, Esteban G, He, Jiang, Kaplan, Robert C, Smith, Nicholas L, Arnett, Donna K, Schwartz, David A, Correa, Adolfo, Guo, Xiuqing, Custer, Brian, Peralta, Juan M, Gui, Hongsheng, Meyers, Deborah A, McGarvey, Stephen T, Chen, Ida Yii-Der, Shoemaker, M Benjamin, Peyser, Patricia A, Broome, Jai G, Gogarten, Stephanie M, Wang, Fei Fei, Wong, Quenna, Kenny, Eimear E, North, Kari E, Launer, Lenore J, Bis, Joshua C, Lasky-Su, Jessica, Bowden, Donald W, Cupples, L Adrienne, Becker, Lewis C, Smith, Jennifer A, Kelly, Tanika N, Aslibekyan, Stella, Heckbert, Susan R, Tiwari, Hemant K, Yang, Ivana V, Heit, John A, Johnsen, Jill M, Curran, Joanne E, Wenzel, Sally E, Weeks, Daniel E, Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P, Buth, Erin J, Rafaels, Nicholas, Loos, Ruth J F, Durda, Peter, Liu, Yongmei, Hou, Lifang, Kachroo, Priyadarshini, Freedman, Barry I, Levy, Daniel, Bielak, Lawrence F, Whitsel, Eric A, Ellinor, Patrick T, Fingerlin, Tasha E, Raffield, Laura M, Armasu, Sebastian M, Wheeler, Marsha M, Blangero, John, Levy, Bruce D, Sheu, Wayne Huey-Herng, Roden, Dan M, Boerwinkle, Eric, Manson, JoAnn E, Taylor, Kent D, Johnson, Andrew D, Auer, Paul L, Kooperberg, Charles, Laurie, Cathy C, Smith, Albert V, Zhao, Hongyu, Lange, Ethan, Rotter, Jerome I, Wilson, James G, Kitzman, Jacob O, Lander, Eric S, Engreitz, Jesse M, Ebert, Benjamin L, Reiner, Alexander P, Abecasis, Gonçalo, Sankaran, Vijay G, Kathiresan, Sekar
Published in Nature (London)

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology

by Sajuthi, Satria P, Everman, Jamie L, Jackson, Nathan D, Saef, Benjamin, Rios, Cydney L, Moore, Camille M, Mak, Angel C Y, Eng, Celeste, Fairbanks-Mahnke, Ana, Salazar, Sandra, Elhawary, Jennifer, Huntsman, Scott, Medina, Vivian, Nickerson, Deborah A, Germer, Soren, Zody, Michael C, Abecasis, Gonçalo, Kang, Hyun Min, Rice, Kenneth M, Kumar, Rajesh, Zaitlen, Noah A, Oh, Sam, Rodríguez-Santana, José, Burchard, Esteban G, Seibold, Max A
Published in Nature communications

Signatures of TOP1 transcription-associated mutagenesis in cancer and germline

by Reijns, Martin A M, Parry, David A, Williams, Thomas C, Nadeu, Ferran, Hindshaw, Rebecca L, Rios Szwed, Diana O, Nicholson, Michael D, Carroll, Paula, Boyle, Shelagh, Royo, Romina, Cornish, Alex J, Xiang, Hang, Ridout, Kate, Schuh, Anna, Aden, Konrad, Palles, Claire, Campo, Elias, Stankovic, Tatjana, Taylor, Martin S, Jackson, Andrew P
Published in Nature (London)

Genetic predisposition to mosaic Y chromosome loss in blood

by Thompson, Deborah J, Genovese, Giulio, Halvardson, Jonatan, Ulirsch, Jacob C, Wright, Daniel J, Terao, Chikashi, Davidsson, Olafur B, Day, Felix R, Sulem, Patrick, Jiang, Yunxuan, Danielsson, Marcus, Davies, Hanna, Dennis, Joe, Dunlop, Malcolm G, Easton, Douglas F, Fisher, Victoria A, Zink, Florian, Houlston, Richard S, Ingelsson, Martin, Kar, Siddhartha, Kerrison, Nicola D, Kinnersley, Ben, Kristjansson, Ragnar P, Law, Philip J, Li, Rong, Loveday, Chey, Mattisson, Jonas, McCarroll, Steven A, Murakami, Yoshinori, Murray, Anna, Olszewski, Pawel, Rychlicka-Buniowska, Edyta, Scott, Robert A, Thorsteinsdottir, Unnur, Tomlinson, Ian, Moghadam, Behrooz Torabi, Turnbull, Clare, Wareham, Nicholas J, Gudbjartsson, Daniel F, Kamatani, Yoichiro, Hoffmann, Eva R, Jackson, Steve P, Stefansson, Kari, Auton, Adam, Ong, Ken K, Machiela, Mitchell J, Loh, Po-Ru, Dumanski, Jan P, Chanock, Stephen J, Forsberg, Lars A, Perry, John R B
Published in Nature (London)

Rapid shifting of a deep magmatic source at Fagradalsfjall volcano, Iceland

by Halldórsson, Sæmundur A, Marshall, Edward W, Caracciolo, Alberto, Matthews, Simon, Bali, Enikő, Rasmussen, Maja B, Ranta, Eemu, Robin, Jóhann Gunnarsson, Guðfinnsson, Guðmundur H, Sigmarsson, Olgeir, Maclennan, John, Jackson, Matthew G, Whitehouse, Martin J, Jeon, Heejin, van der Meer, Quinten H A, Mibei, Geoffrey K, Kalliokoski, Maarit H, Repczynska, Maria M, Rúnarsdóttir, Rebekka Hlín, Sigurðsson, Gylfi, Pfeffer, Melissa Anne, Scott, Samuel W, Kjartansdóttir, Ríkey, Kleine, Barbara I, Oppenheimer, Clive, Aiuppa, Alessandro, Ilyinskaya, Evgenia, Bitetto, Marcello, Giudice, Gaetano, Stefánsson, Andri
Published in Nature (London)

Early mucosal events promote distinct mucosal and systemic antibody responses to live attenuated influenza vaccine

by Thwaites, Ryan S, Uruchurtu, Ashley S S, Negri, Victor Augusti, Cole, Megan E, Singh, Nehmat, Poshai, Nelisa, Jackson, David, Hoschler, Katja, Baker, Tina, Scott, Ian C, Ros, Xavier Romero, Cohen, Emma Suzanne, Zambon, Maria, Pollock, Katrina M, Hansel, Trevor T, Openshaw, Peter J M
Published in Nature communications

SARS-CoV-2 evolution during treatment of chronic infection

by Kemp, Steven A, Collier, Dami A, Datir, Rawlings P, Ferreira, Isabella A T M, Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J, Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E, Briggs, John A G, van Gils, Marit J, Smith, Kenneth G C, Bradley, John R, Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D, Goldstein, Richard A, Smielewska, Anna, Skittrall, Jordan P, Gouliouris, Theodore, Goodfellow, Ian G, Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J R, McCoy, Laura E, Gupta, Ravindra K
Published in Nature (London)

Mutational signature in colorectal cancer caused by genotoxic pks + E. coli

by Pleguezuelos-Manzano, Cayetano, Puschhof, Jens, Rosendahl Huber, Axel, van Hoeck, Arne, Wood, Henry M, Nomburg, Jason, Gurjao, Carino, Manders, Freek, Dalmasso, Guillaume, Stege, Paul B, Paganelli, Fernanda L, Geurts, Maarten H, Beumer, Joep, Mizutani, Tomohiro, Miao, Yi, van der Linden, Reinier, van der Elst, Stefan, Garcia, K Christopher, Top, Janetta, Willems, Rob J L, Giannakis, Marios, Bonnet, Richard, Quirke, Phil, Meyerson, Matthew, Cuppen, Edwin, van Boxtel, Ruben, Clevers, Hans
Published in Nature (London)

Improved production of the non-native cofactor F 420 in Escherichia coli

by Shah, Mihir V, Nazem-Bokaee, Hadi, Antoney, James, Kang, Suk Woo, Jackson, Colin J, Scott, Colin
Published in Scientific reports

LAGOS-NE: a multi-scaled geospatial and temporal database of lake ecological context and water quality for thousands of US lakes

by Soranno, Patricia A, Bacon, Linda C, Beauchene, Michael, Bednar, Karen E, Bissell, Edward G, Boudreau, Claire K, Boyer, Marvin G, Bremigan, Mary T, Carpenter, Stephen R, Carr, Jamie W, Cheruvelil, Kendra S, Christel, Samuel T, Claucherty, Matt, Collins, Sarah M, Conroy, Joseph D, Downing, John A, Dukett, Jed, Fergus, C Emi, Filstrup, Christopher T, Funk, Clara, Gonzalez, Maria J, Green, Linda T, Gries, Corinna, Halfman, John D, Hamilton, Stephen K, Hanson, Paul C, Henry, Emily N, Herron, Elizabeth M, Hockings, Celeste, Jackson, James R, Jacobson-Hedin, Kari, Janus, Lorraine L, Jones, William W, Jones, John R, Keson, Caroline M, King, Katelyn B S, Kishbaugh, Scott A, Lapierre, Jean-Francois, Lathrop, Barbara, Latimore, Jo A, Lee, Yuehlin, Lottig, Noah R, Lynch, Jason A, Matthews, Leslie J, McDowell, William H, Moore, Karen E B, Neff, Brian P, Nelson, Sarah J, Oliver, Samantha K, Pace, Michael L, Pierson, Donald C, Poisson, Autumn C, Pollard, Amina I, Post, David M, Reyes, Paul O, Rosenberry, Donald O, Roy, Karen M, Rudstam, Lars G, Sarnelle, Orlando, Schuldt, Nancy J, Scott, Caren E, Skaff, Nicholas K, Smith, Nicole J, Spinelli, Nick R, Stachelek, Jemma, Stanley, Emily H, Stoddard, John L, Stopyak, Scott B, Stow, Craig A, Tallant, Jason M, Tan, Pang-Ning, Thorpe, Anthony P, Vanni, Michael J, Wagner, Tyler, Watkins, Gretchen, Weathers, Kathleen C, Webster, Katherine E, White, Jeffrey D, Wilmes, Marcy K, Yuan, Shuai
Published in Gigascience