Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

by Wiegman, Coen H., PhD, Michaeloudes, Charalambos, PhD, Haji, Gulammehdi, MD, Narang, Priyanka, PhD, Clarke, Colin J., MSc, Russell, Kirsty E., PhD, Bao, Wuping, MD, Pavlidis, Stelios, PhD, Barnes, Peter J., MD, Kanerva, Justin, MSc, Bittner, Anton, PhD, Rao, Navin, PhD, Murphy, Michael P., PhD, Kirkham, Paul A., PhD, Chung, Kian Fan, MD, Adcock, Ian M., PhD
Published in Journal of allergy and clinical immunology

Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19

by Milross, Luke, Hunter, Bethany, McDonald, David, Merces, George, Thomson, Amanda, Hilkens, Catharien M.U., Wills, John, Rees, Paul, Jiwa, Kasim, Cooper, Nigel, Majo, Joaquim, Ashwin, Helen, Duncan, Christopher J.A., Kaye, Paul M., Bayraktar, Omer Ali, Filby, Andrew, Fisher, Andrew J.
Published in EBioMedicine

Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial

by Jankowski, Janusz A Z, de Caestecker, John, Love, Sharon B, Reilly, Gavin, Watson, Peter, Sanders, Scott, Ang, Yeng, Morris, Danielle, Bhandari, Pradeep, Brooks, Claire, Attwood, Stephen, Harrison, Rebecca, Barr, Hugh, Moayyedi, Paul, Ragunath, Krish, Rameh, Bashir, Fullarton, Grant, Tucker, Art, Penman, Ian, Rodgers, Colin, Neale, James, Edwards, Cathryn, Wise, Adelyn, Jones, Stephen, Church, Nicholas, Vaidya, Kishor, Balata, Sherzad, Todd, John, Gibbons, Michael, Johnston, David, Anderson, Mark, Davies, Gareth, Dickey, William, Murdock, Andrew, Turner, Graham, Goddard, Andrew, Gore, Stephen, Haigh, Chris, Harding, Timothy, Jackson, Lucina, Murray, Iain, Worthingon, Joy, Lee, Thomas, Lim, Peik Loon, McLoughlin, James, Macdonald, Christopher, Mairs, Philip, Monk, David, Preston, Sean, Pugh, Stirling, Smart, Howard, Soliman, Ashraf, Isaacs, Peter, Aldulaimi, David, Trudgill, Nigel, Benhamida, Abduljalil, Bell, Andrew, Boulton-Jones, Robert, Daneshmend, Tawfique, Suzuki, Hisaharu, Fitzgerald, Rebecca, Ransford, Rupert, Rahman, Mohammad Mesbahur, Tebala, Giovanni Domenico, Hallissey, Michael, Kelly, Carrie, Hickish, Tamas, Taha, Ali, Rademaker, Johan, Whitehead, Mark, Kelly, Sean, Phull, Perminder, Sharma, Naveen, Perry, Ian, Sankara-Raman, Vankatraman, Ali, Haythem, Khan, Iqbal, Curtis, Howard, Wadley, Martin, Stone, Adam, Sukumaran, Sumesh, Higham, Andrew, Lewis, Stephen, Haycock, Adam, Usselmann, Bernhard, Johnston, Simon Douglas, Tham, Tony, Campbell, Stewart, Douds, Andrew, Dunn, Jason, Sargeant, Ian, Narain, Mark, Maynard, Nick, Chilton, Andrew, Green, Susi, Loft, Duncan, Decadt, Bart, Mendall, Michael, Heydtmann, Mathis, Fisher, Neil
Published in The Lancet (British edition)

FOXD3 Regulates VISTA Expression in Melanoma

by Rosenbaum, Sheera R., Knecht, Meghan, Mollaee, Mehri, Zhong, Zhijiu, Erkes, Dan A., McCue, Peter A., Chervoneva, Inna, Berger, Adam C., Lo, Jennifer A., Fisher, David E., Gershenwald, Jeffrey E., Davies, Michael A., Purwin, Timothy J., Aplin, Andrew E.
Published in Cell reports (Cambridge)

Predictive modeling of addiction lapses in a mobile health application

by Chih, Ming-Yuan, M.H.A., M.S, Patton, Timothy, B.S, McTavish, Fiona M., M.S, Isham, Andrew J., M.S, Judkins-Fisher, Chris L., B.S, Atwood, Amy K., Ph.D, Gustafson, David H., Ph.D
Published in Journal of substance abuse treatment

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four random...

by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Feng, Shuo, Marshall, Richard P, Milan, Eveline P, Pollock, Katrina M, Ramasamy, Maheshi N, Robinson, Hannah, Andrade, Claudia Sala, Barker, Debbie, Bates, Louise, Batten, Alexander, Berzenyi, Daniella, Bird, Adam, Blundell, Susannah R., Budd, William, Cabrera Puig, Ingrid, Calvert, Anna, Carvalho, Yasmin de M., Castro, Thais R.Y., Chiplin, Emily, Cifuentes, Liliana, Danos, Zsofia, Dantas, Maria T.D.C., Davies, Sophie, Desai, Amisha, Drake-Brockman, Rachael, Edwards, Mandy, Edwards, Nick J., El Muhanna, Omar M., Ellison-Handley, Branwen, Fedosyuk, Sofiya, Fisher, Richard, Fofie, Hazel, Franco, Marilia M., Fuskova, Michelle, Godwin, Kerry, Gokani, Karishma, Gonçalves, Maria Luisa Freire, Goodall, Jack, Harris-Wright, Tara A., Howell, Nicola, Humphreys, Jonathan, Iyer, Vidyashankara, Jackson, Susan, Jaumdally, Shameem, Jorge, Marianna Rocha, Kellett Wright, Johanna, Kelly, Elizabeth J., Kelly, Dearbhla M., Kidd, Sarah, Larwood, Jessica P.J., Lees, Emily A., Lelliott, Alice, Leung, Stephanie, Manning, Nicola, Mazur, Olga, McGlashan, Joanna, Megson, Clare, Mesquita, Ana Carolina F., Mitton, Celia, Morrison, Hazel, Morselli, Franca, Oliveira, Catarina, Oosthuizen, Angela, Owen, David R.J., Parracho, Helena M. R.T., Perez, Ana Luiza, Perinpanathan, Tanaraj, Perumal, Rubeshan, Plank, Mary, Proud, Pamela C., Rajeswaran, Thurkka, Rees, Byron, Rhead, Sarah, Richards, Alexander, Roberts, Hannah, Robinson, Ryan E., Rudiansyah, Indra, Saunders, Jack E., Screaton, Gavin R., Sorley, Kim, Spencer, Alexandra J., Spoors, Louise, Stein, Ricardo, Strickland, Louise H., Sturdy, Ann, Sutton, Natalina, Taoushanis, Carol, Thomas, Merin, Tinoco, Lygia Accioly, Tomic, Adriana, Truby, Adam, Underwood, Benjamin R., Vichos, Iason, Watkins, Bridget, Wellbelove, Zoe, White, Caroline, Willingham, Silvia
Published in The Lancet (British edition)

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

by Turajlic, Samra, Xu, Hang, Litchfield, Kevin, Rowan, Andrew, Horswell, Stuart, Chambers, Tim, O’Brien, Tim, Lopez, Jose I., Watkins, Thomas B.K., Nicol, David, Stares, Mark, Challacombe, Ben, Hazell, Steve, Chandra, Ashish, Mitchell, Thomas J., Au, Lewis, Eichler-Jonsson, Claudia, Jabbar, Faiz, Soultati, Aspasia, Chowdhury, Simon, Rudman, Sarah, Lynch, Joanna, Fernando, Archana, Stamp, Gordon, Nye, Emma, Stewart, Aengus, Xing, Wei, Smith, Jonathan C., Escudero, Mickael, Huffman, Adam, Matthews, Nik, Elgar, Greg, Phillimore, Ben, Costa, Marta, Begum, Sharmin, Ward, Sophia, Salm, Max, Boeing, Stefan, Fisher, Rosalie, Spain, Lavinia, Navas, Carolina, Grönroos, Eva, Hobor, Sebastijan, Sharma, Sarkhara, Aurangzeb, Ismaeel, Lall, Sharanpreet, Polson, Alexander, Varia, Mary, Horsfield, Catherine, Fotiadis, Nicos, Pickering, Lisa, Schwarz, Roland F., Silva, Bruno, Herrero, Javier, Luscombe, Nick M., Jamal-Hanjani, Mariam, Rosenthal, Rachel, Birkbak, Nicolai J., Wilson, Gareth A., Pipek, Orsolya, Ribli, Dezso, Krzystanek, Marcin, Csabai, Istvan, Szallasi, Zoltan, Gore, Martin, McGranahan, Nicholas, Van Loo, Peter, Campbell, Peter, Larkin, James, Swanton, Charles
Published in Cell

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

by Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart
Published in The Lancet (British edition)

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

by Hiley, Crispin T., Wilson, Gareth A., Birkbak, Nicolai J., Veeriah, Selvaraju, Herrero, Javier, Swanton, Charles, Swanton, Charles, Czyzewska-Khan, Justyna, Gorman, Pat, Wilson, Gareth, Watkins, Thomas B.K., McGranahan, Nicholas, Mitter, Richard, Escudero, Mickael, Rowan, Andrew, Xu, Hang, Turajlic, Samra, Stone, Richard Kevin, Denner, Tamara, Costa, Marta, Phillimore, Ben, Joshi, Kroopa, Furness, Andrew, Ben Aissa, Assma, Wong, Yien Ning Sophia, Quezada, Sergio, Hartley, John A., Lowe, Helen L., Herrero, Javier, Lawrence, David, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Janes, Sam M., Thakrar, Ricky, Papadatos-Pastos, Dionysis, Choudhary, Junaid, Califano, Raffaele, Taylor, Paul, Crosbie, Phil, Moss, Stuart, Idries, Faiza, Bishop, Paul, Chaturved, Anshuman, Quinn, Anne Marie, Doran, Helen, Leek, Angela, Blackhall, Fiona, Chemi, Francesca, Gulati, Sakshi, Naidu, Babu, Trotter, Simon, Bellamy, Mary, Bancroft, Hollie, Middleton, Gary, Shaw, Jacqui A., Le Quesne, John, Rathinam, Sridhar, Monteiro, William, Marshall, Hilary, Riley, Joan, Primrose, Lindsay, Anand, Girija, Nicolson, Marianne, Palmer, Shirley, Buchan, Keith, Chetty, Mahendran, Edwards, Alison, Morgan, Fiona, Davies, Helen, Verjee, Azmina, MacKenzie, Mairead, Hackshaw, Allan, Smith, Sean, Alzetani, Aiman, Shaw, Emily, Rice, Alexandra, Raubenheimer, Hilgardt, Proli, Chiara, Cufari, Maria Elena, Bhayani, Harshil, Bakar, Yusura, Mensah, Natalie, Ambrose, Lyn, Devaraj, Anand, Chavan, Hema, Lau, Kelvin, Sheaff, Michael, Schmid, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-sellers, Melanie, Prakash, Vineet, Horey, Tracey, Hill, Jennifer, Suvarna, Kim, Keerio, Allah Dino, Feeney, Sarah, Asante-Siaw, Julius, Dessimoz, Christophe
Published in Cell

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

by Cohen, Jeffrey A, Prof, Coles, Alasdair J, PhD, Arnold, Douglas L, Prof, Confavreux, Christian, Prof, Fox, Edward J, MD, Hartung, Hans-Peter, Prof, Havrdova, Eva, Prof, Selmaj, Krzysztof W, Prof, Weiner, Howard L, Prof, Fisher, Elizabeth, PhD, Brinar, Vesna V, MD, Giovannoni, Gavin, Prof, Stojanovic, Miroslav, MD, Ertik, Bella I, MD, Lake, Stephen L, ScD, Margolin, David H, MD, Panzara, Michael A, MD, Compston, D Alastair S, Prof
Published in The Lancet (British edition)

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

by Coles, Alasdair J, Dr, Twyman, Cary L, MD, Arnold, Douglas L, Prof, Cohen, Jeffrey A, Prof, Confavreux, Christian, Prof, Fox, Edward J, MD, Hartung, Hans-Peter, Prof, Havrdova, Eva, Prof, Selmaj, Krzysztof W, Prof, Weiner, Howard L, Prof, Miller, Tamara, MD, Fisher, Elizabeth, PhD, Sandbrink, Rupert, MD, Lake, Stephen L, ScD, Margolin, David H, MD, Oyuela, Pedro, MD, Panzara, Michael A, MD, Compston, D Alastair S, Prof
Published in The Lancet (British edition)

CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, mult...

by O'Hara, Mark H, O'Reilly, Eileen M, Varadhachary, Gauri, Wolff, Robert A, Wainberg, Zev A, Ko, Andrew H, Fisher, George, Rahma, Osama, Lyman, Jaclyn P, Cabanski, Christopher R, Mick, Rosemarie, Gherardini, Pier Federico, Kitch, Lacey J, Xu, Jingying, Samuel, Theresa, Karakunnel, Joyson, Fairchild, Justin, Bucktrout, Samantha, LaVallee, Theresa M, Selinsky, Cheryl, Till, Jacob E, Carpenter, Erica L, Alanio, Cécile, Byrne, Katelyn T, Chen, Richard O, Trifan, Ovid C, Dugan, Ute, Horak, Christine, Hubbard-Lucey, Vanessa M, Wherry, E John, Ibrahim, Ramy, Vonderheide, Robert H
Published in The lancet oncology

High prevalence of triazole resistance in clinical Aspergillus fumigatus isolates in a specialist cardiothoracic centre

by Abdolrasouli, Alireza, Scourfield, Andrew, Rhodes, Johanna, Shah, Anand, Elborn, J. Stuart, Fisher, Matthew C., Schelenz, Silke, Armstrong-James, Darius
Published in International journal of antimicrobial agents

Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: The role of stress and of antipsychotic treatment

by Mondelli, Valeria, Dazzan, Paola, Hepgul, Nilay, Di Forti, Marta, Aas, Monica, D'Albenzio, Alessandro, Di Nicola, Marco, Fisher, Helen, Handley, Rowena, Marques, Tiago Reis, Morgan, Craig, Navari, Serena, Taylor, Heather, Papadopoulos, Andrew, Aitchison, Katherine J, Murray, Robin M, Pariante, Carmine M
Published in Schizophrenia research

Active symptom control with or without chemotherapy in the treatment of patients with malignant pleural mesothelioma (MS01): a multicentre randomised trial

by Muers, Martin F, FRCP, Stephens, Richard J, Fisher, Patricia, FRCR, Darlison, Liz, BSc Hons, Higgs, Christopher MB, MD, Lowry, Erica, BA, Nicholson, Andrew G, Prof, O'Brien, Mary, MD, Peake, Michael, FRCP, Rudd, Robin, MD, Snee, Michael, DM, Steele, Jeremy, MD, Girling, David J, FRCP, Nankivell, Matthew, MSc, Pugh, Cheryl, BSc Hons, Parmar, Mahesh KB, Prof
Published in The Lancet (British edition)

Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial

by Kneebone, Andrew, Fraser-Browne, Carol, Duchesne, Gillian M, Fisher, Richard, Frydenberg, Mark, Herschtal, Alan, Williams, Scott G, Brown, Chris, Delprado, Warick, Haworth, Annette, Joseph, David J, Martin, Jarad M, Matthews, John H L, Millar, Jeremy L, Sidhom, Mark, Spry, Nigel, Tang, Colin I, Turner, Sandra, Wiltshire, Kirsty L, Woo, Henry H, Davis, Ian D, Lim, Tee S, Pearse, Maria
Published in The lancet oncology

The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort

by Pells, Greta, Mells, George F, Carbone, Marco, Newton, Julia L, Bathgate, Andrew J, Burroughs, Andrew K, Heneghan, Michael A, Neuberger, James M, Day, Darren B, Ducker, Samantha J, Sandford, Richard N, Alexander, Graeme J, Jones, David E.J
Published in Journal of hepatology

Socioeconomic Status as a Predictor of Mortality in Patients Admitted with Atrial Fibrillation

by Kargoli, Faraj, MD, MPH, Shulman, Eric, MD, Aagaard, Philip, MD, PhD, Briceno, David F., MD, Hoch, Ethan, MD, Di Biase, Luigi, MD, PhD, Fisher, John D., MD, Gross, Jay, MD, Kim, Soo G., MD, Krumerman, Andrew, MD, Ferrick, Kevin J., MD
Published in The American journal of cardiology

Ischemic and Bleeding Events in Patients with Myocardial Infarction Undergoing Percutaneous Coronary Intervention Who Require Oral Anticoagulation: Insights from the Canadian Obser...

by Sra, Steven, MD, Tan, Mary K., MSc, Mehta, Shamir R., MD, MSc, Fisher, Harold N., MD, Déry, Jean-Pierre, MD, Welsh, Robert C., MD, Eisenberg, Mark J., MD, MPH, Overgaard, Christopher B., MD, MSc, Rose, Barry F., MD, Siega, Anthony J. Della, MD, Cheema, Asim N., MD, Wong, Brian Y.L., MD, Henderson, Mark A., MD, Lutchmedial, Sohrab, MD, CM, Lavi, Shahar, MD, Goodman, Shaun G., MD, MSc, Yan, Andrew T., MD
Published in The American heart journal

Prognostic Value of Automatically Detected Early Repolarization

by Aagaard, Philip, MD, PhD, Shulman, Eric, MD, Di Biase, Luigi, MD, PhD, Fisher, John D., MD, Gross, Jay N., MD, Kargoli, Faraj, MD, MPH, Kim, Soo G., MD, Palma, Eugen C., MD, Ferrick, Kevin J., MD, Krumerman, Andrew, MD
Published in The American journal of cardiology