Highly efficient ‘hit-and-run’ genome editing with unconcentrated lentivectors carrying Vpr.Prot.Cas9 protein produced from RRE-containing transcripts

by Indikova, Ivana, Indik, Stanislav
Published in Nucleic acids research

Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion

by Reddy, K Sony, Amlabu, Emmanuel, Pandey, Alok K, Mitra, Pallabi, Chauhan, Virander S, Gaur, Deepak
Published in Proceedings of the National Academy of Sciences - PNAS

GeneralizedDTA: combining pre-training and multi-task learning to predict drug-target binding affinity for unknown drug discovery

by Lin, Shaofu, Shi, Chengyu, Chen, Jianhui
Published in BMC bioinformatics

Combined Adjuvant of Poly I:C Improves Antitumor Effects of CAR-T Cells

by Di, Shengmeng, Zhou, Min, Pan, Zeyan, Sun, Ruixin, Chen, Muhua, Jiang, Hua, Shi, Bizhi, Luo, Hong, Li, Zonghai
Published in Frontiers in oncology

Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration

by Guarin, Marlly, Faelens, Ruben, Giusti, Arianna, De Croze, Noémie, Léonard, Marc, Cabooter, Deirdre, Annaert, Pieter, de Witte, Peter, Ny, Annelii
Published in Scientific reports

Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies

by Odunsi, Adekunle, McGray, A J Robert, Miliotto, Anthony, Zhang, Yali, Wang, Jianming, Abiola, Adebukola, Eppolito, Cheryl, Huang, Ruea-Yea
Published in Journal for immunotherapy of cancer

Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer

by Hung, Chiu-Lien, Liu, Hao-Hsuan, Fu, Chih-Wei, Yeh, Hsun-Hao, Hu, Tsan-Lin, Kuo, Zong-Keng, Lin, Yu-Chin, Jhang, Mei-Ru, Hwang, Chrong-Shiong, Hsu, Hung-Chih, Kung, Hsing-Jien, Wang, Ling-Yu
Published in EBioMedicine

Computed tomographic cervical myelography in horses: Technique and findings in 51 clinical cases

by Gough, Sarah L., Anderson, Jonathan D. C., Dixon, Jonathon J
Published in Journal of veterinary internal medicine

Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

by Yi, Jingjie, Tavana, Omid, Li, Huan, Wang, Donglai, Baer, Richard J, Gu, Wei
Published in Nature communications

Targeting signaling pathways in prostate cancer: mechanisms and clinical trials

by He, Yundong, Xu, Weidong, Xiao, Yu-Tian, Huang, Haojie, Gu, Di, Ren, Shancheng
Published in Signal transduction and targeted therapy

Bisphosphonates, atherosclerosis and vascular calcification: update and systematic review of clinical studies

by Caffarelli, Carla, Montagnani, Andrea, Nuti, Ranuccio, Gonnelli, Stefano
Published in Clinical interventions in aging

Cellular immunotherapy for hematological malignancy: recent progress and future perspectives

by Xu, Zhengli, Huang, Xiaojun
Published in Cancer biology & medicine

Hippo pathway mediates resistance to cytotoxic drugs

by Gujral, Taranjit S., Kirschner, Marc W.
Published in Proceedings of the National Academy of Sciences - PNAS

Long-Term Efficacy of Systemic Multiexon Skipping Targeting Dystrophin Exons 45–55 With a Cocktail of Vivo-Morpholinos in Mdx52 Mice

by Echigoya, Yusuke, Aoki, Yoshitsugu, Miskew, Bailey, Panesar, Dharminder, Touznik, Aleksander, Nagata, Tetsuya, Tanihata, Jun, Nakamura, Akinori, Nagaraju, Kanneboyina, Yokota, Toshifumi
Published in Molecular therapy. Nucleic acids

Metabolic fate of polyphenols in the human superorganism

by van Duynhoven, John, Vaughan, Elaine E., Jacobs, Doris M., Kemperman, Robèr A., van Velzen, Ewoud J. J., Gross, Gabriele, Roger, Laure C., Possemiers, Sam, Smilde, Age K., Doré, Joël, Westerhuis, Johan A., Van de Wiele, Tom, Gordon, Jeffrey I.
Published in Proceedings of the National Academy of Sciences - PNAS

STAT3-blocked whole-cell hepatoma vaccine induces cellular and humoral immune response against HCC

by Han, Qiuju, Wang, Yaqun, Pang, Min, Zhang, Jian
Published in Journal of experimental & clinical cancer research

Building protein-protein interaction networks for Leishmania species through protein structural information

by Dos Santos Vasconcelos, Crhisllane Rafaele, de Lima Campos, Túlio, Rezende, Antonio Mauro
Published in BMC bioinformatics

Sotorasib in KRASG12C mutated lung cancer: Can we rule out cracking KRAS led to worse overall survival?

by Olivier, Timothée, Haslam, Alyson, Prasad, Vinay
Published in Translational oncology

OpenWorkstation: A modular open-source technology for automated in vitro workflows

by Eggert, Sebastian, Mieszczanek, Pawel, Meinert, Christoph, Hutmacher, Dietmar W
Published in HardwareX

Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review

by Iadarola, Nicolas D., Niciu, Mark J., Richards, Erica M., Vande Voort, Jennifer L., Ballard, Elizabeth D., Lundin, Nancy B., Nugent, Allison C., Machado-Vieira, Rodrigo, Zarate, Carlos A.
Published in Therapeutic Advances in Chronic Disease