Local and Systemic Delivery of a Stable Aspirin-Triggered Lipoxin Prevents Neutrophil Recruitment in vivo

by Clish, Clary B., O'Brien, Jennifer A., Gronert, Karsten, Stahl, Gregory L., Petasis, Nicos A., Serhan, Charles N.
Published in Proceedings of the National Academy of Sciences - PNAS

A Synthetic Antagonist for the Peroxisome Proliferator-activated Receptor γ Inhibits Adipocyte Differentiation

by Wright, Harold M., Clish, Clary B., Mikami, Toshiyuki, Hauser, Stefanie, Yanagi, Kazunori, Hiramatsu, Ryuji, Serhan, Charles N., Spiegelman, Bruce M.
Published in The Journal of biological chemistry

Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic...

by Serhan, C N, Clish, C B, Brannon, J, Colgan, S P, Gronert, K, Chiang, N
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

by Zhong, Lei, D'Urso, Agustina, Toiber, Debra, Sebastian, Carlos, Henry, Ryan E, Vadysirisack, Douangsone D, Guimaraes, Alexander, Marinelli, Brett, Wikstrom, Jakob D, Nir, Tomer, Clish, Clary B, Vaitheesvaran, Bhavapriya, Iliopoulos, Othon, Kurland, Irwin, Dor, Yuval, Weissleder, Ralph, Shirihai, Orian S, Ellisen, Leif W, Espinosa, Joaquin M, Mostoslavsky, Raul
Published in Cell

Oxidoreductases in Lipoxin A sub(4) Metabolic Inactivation: A novel role for 15-oxoprostaglandin 13-reductase/leukotriene B sub(4) 12-hydroxydehydrogenase in inflammation

by Clish, C B, Levy, B D, Chiang, N, Tai, H H, Serhan, C N
Published in The Journal of biological chemistry

Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation

by Clish, C B, Levy, B D, Chiang, N, Tai, H H, Serhan, C N
Published in The Journal of biological chemistry

Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis

by Wang, Ying-Hua, Israelsen, William J, Lee, Dongjun, Yu, Vionnie W C, Jeanson, Nathaniel T, Clish, Clary B, Cantley, Lewis C, Vander Heiden, Matthew G, Scadden, David T
Published in Cell

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

by Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.
Published in Cell

Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

by Chao, Chun-Cheih, Gutiérrez-Vázquez, Cristina, Rothhammer, Veit, Mayo, Lior, Wheeler, Michael A., Tjon, Emily C., Zandee, Stephanie E.J., Blain, Manon, de Lima, Kalil Alves, Takenaka, Maisa C., Avila-Pacheco, Julian, Hewson, Patrick, Liu, Lei, Sanmarco, Liliana M., Borucki, Davis M., Lipof, Gabriel Z., Trauger, Sunia A., Clish, Clary B., Antel, Jack P., Prat, Alexandre, Quintana, Francisco J.
Published in Cell

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

by Fanning, Saranna, Haque, Aftabul, Imberdis, Thibaut, Baru, Valeriya, Barrasa, M. Inmaculada, Nuber, Silke, Termine, Daniel, Ramalingam, Nagendran, Ho, Gary P.H., Noble, Tallie, Sandoe, Jackson, Lou, Yali, Landgraf, Dirk, Freyzon, Yelena, Newby, Gregory, Soldner, Frank, Terry-Kantor, Elizabeth, Kim, Tae-Eun, Hofbauer, Harald F., Becuwe, Michel, Jaenisch, Rudolf, Pincus, David, Clish, Clary B., Walther, Tobias C., Farese, Robert V., Srinivasan, Supriya, Welte, Michael A., Kohlwein, Sepp D., Dettmer, Ulf, Lindquist, Susan, Selkoe, Dennis
Published in Molecular cell

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

by Finley, Lydia W. S, Lee, Jaewon, Souza, Amanda, Desquiret-Dumas, Valérie, Bullock, Kevin, Rowe, Glenn C, Procaccio, Vincent, Clish, Clary B, Arany, Zoltan, Haigis, Marcia C
Published in Proceedings of the National Academy of Sciences - PNAS

Large scale proteomic studies create novel privacy considerations

by Hill, Andrew C, Guo, Claire, Litkowski, Elizabeth M, Manichaikul, Ani W, Yu, Bing, Konigsberg, Iain R, Gorbet, Betty A, Lange, Leslie A, Pratte, Katherine A, Kechris, Katerina J, DeCamp, Matthew, Coors, Marilyn, Ortega, Victor E, Rich, Stephen S, Rotter, Jerome I, Gerzsten, Robert E, Clish, Clary B, Curtis, Jeffrey L, Hu, Xiaowei, Obeidat, Ma-En, Morris, Melody, Loureiro, Joseph, Ngo, Debby, O'Neal, Wanda K, Meyers, Deborah A, Bleecker, Eugene R, Hobbs, Brian D, Cho, Michael H, Banaei-Kashani, Farnoush, Bowler, Russell P
Published in Scientific reports

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise

by Adkins, Joshua N., Dasari, Surendra, Drugan, Jonelle K., Radom-Aizik, Shlomit, Snyder, Michael P., Walsh, Martin J., Adkins, Joshua N., Amar, David, Evans, Charles R., Li, Yafeng, Radom-Aizik, Shlomit, Sanford, James A., Schenk, Simon, Lee Alekel, D., Boyce, Amanda T., Fleg, Jerome L., McGowan, Joan A., Nierras, Concepcion, Pai, Vinay, Peterson, Charlotte, Ramos, Ed, Roary, Mary C., Xia, Ashley, Rooney, Jessica, Miller, Michael E., Ambrosius, Walter T., Jack Rejeski, W., Lu, Ching-ju, Raue, Ulrika, Lester, Bridget, Bergman, Bryan C., Bessesen, David H., Jankowski, Catherine M., Moreau, Kerrie L., Schauer, Irene E., Huffman, Kim M., Johnson, Johanna L., Kelly, Leslie, Broskey, Nick, Goodpaster, Bret H., Sparks, Lauren M., Cooper, Dan M., Haddad, Fadia, Rankinen, Tuomo, Ravussin, Eric, Johannsen, Neil, Harris, Melissa, Jakicic, John M., Newman, Anne B., Forman, Daniel D., Rogers, Renee J., Page, Lindsay C., Rasmussen, Blake B., Musi, Nicolas, Patel, Darpan, Gelfond, Jonathan, Burns, Aisling, Bamman, Marcas M., Buford, Thomas W., Bodine, Sue C., Hirshman, Michael F., Albertson, Brent G., Qian, Wei-Jun, Piehowski, Paul, Gritsenko, Marina A., Hansen, Joshua N., Carr, Steve, Jean-Beltran, Pierre M., Keshishian, Hasmik, Krug, Karsten, Pearce, Cadence, Ivanova, Anna A., Ortlund, Eric A., Sealfon, Stuart C., Zaslavsky, Elena, Nair, Venugopalan, Li, SiDe, Sun, Yifei, Pincas, Nhanna, Seenarine, Nitish, Lappalainen, Tuuli, Sreekumaran Nair, K., Gay, Nicole R., Zebarjadi, Navid, Burant, Charles F., Li, Jun Z., Kachman, Maureen, Raskind, Alexander B., Gerszten, Robert, Robbins, Jeremy, Newgard, Christopher B., Jimenez-Morales, David, Raja, Archana, Zhen, Jimmy, Suk Kim, Young, Christle, Jeffrey W., Marwaha, Shruti, Hershman, Steven G., Hastie, Trevor, Tibshirani, Robert
Published in Cell

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

by Rusu, Victor, Hoch, Eitan, Mercader, Josep M., Tenen, Danielle E., Gymrek, Melissa, Hartigan, Christina R., DeRan, Michael, Guzman, Gaelen, Deik, Amy A., Pierce, Kerry A., Dennis, Courtney, Clish, Clary B., Carr, Steven A., Wagner, Bridget K., Chen, Brian H., Ng, Maggie C.Y., Chen, Brian H., Guo, Xiuqing, Liu, Jiankang, Bielinski, Suzette J., Nalls, Michael A., Rasmussen-Torvik, Laura J., Evans, Daniel S., Sun, Yan V., Patel, Sanjay R., Lu, Yingchang, Long, Jirong, Armstrong, Loren L., Yang, Lingyao, Snively, Beverly M., Palmer, Nicholette D., Mudgal, Poorva, Keene, Keith L., Freedman, Barry I., Goodarzi, Mark O., Correa, Adolfo, Sims, Mario, Couper, David, Pankow, James S., Boerwinkle, Eric, Adeyemo, Adebowale, Doumatey, Ayo, Vaidya, Dhananjay, Sedor, John R., Kabagambe, Edmond K., McKnight, Barbara, Rice, Kenneth, Bielak, Lawrence F., Gottesman, Omri, Cai, Qiuyin, Zheng, Wei, Blot, William J., Lowe, William L., Pacheco, Jennifer A., Crawford, Dana C., Rich, Stephen S., Shu, Xiao-Ou, Loos, Ruth J.F., Borecki, Ingrid B., Peyser, Patricia A., Fornage, Myriam, Evans, Michele K., Becker, Diane M., Kao, W.H. Linda, Wilson, James G., Sale, Michèle M., Liu, Simin, Rotimi, Charles N., Bowden, Donald W., Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Manning, Alisa, Caulkins, Lizz, Burtt, Noël P., Flannick, Jason, Patterson, Nick, Tusié-Luna, Teresa, Altshuler, David, Florez, Jose C., Martínez-Hernández, Angélica, Centeno-Cruz, Federico, Zerrweck, Carlos, Contreras-Cubas, Cecilia, Córdova, Emilio, Soberón, Xavier, Orozco, Lorena, González-Villalpando, María Elena, Haiman, Christopher A., Le Marchand, Loic, Kolonel, Laurence, Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, Rodríguez-Guillén, Rosario, Gómez, Donají, Alvirde, Ulices, Cortes, Maria L., Centeno-Cruz, Federico, Zerrweck, Carlos, Orozco, Lorena, Jacobs, Suzanne B.R.
Published in Cell

Skeletal muscle transcriptional coactivator PGC-1[alpha] mediates mitochondrial, but not metabolic, changes during calorie restriction

by Finley, Lydia W S, Lee, Jaewon, Souza, Amanda, Desquiret-Dumas, Valérie, Bullock, Kevin, Rowe, Glenn C, Procaccio, Vincent, Clish, Clary B, Arany, Zoltan, Haigis, Marcia C
Published in Proceedings of the National Academy of Sciences - PNAS

Skeletal muscle transcriptional coactivator PGC-lα mediates mitochondrial, but not metabolic, changes during calorie restriction

by Finley, Lydia W. S., Lee, Jaewon, Souza, Amanda, Desquiret-Dumas, Valérie, Bullock, Kevin, Rowe, Glenn C., Procaccio, Vincent, Clish, Clary B., Arany, Zoltan, Haigis, Marcia
Published in Proceedings of the National Academy of Sciences - PNAS