Identifying and understanding factors that affect the translation of therapies from the laboratory to patients: a study protocol [version 2; peer review: 2 approved]

by Lalu, Manoj M, Montroy, Joshua, Begley, C. Glenn, Bubela, Tania, Hunniford, Victoria, Ripsman, David, Wesch, Neil, Kimmelman, Jonathan, Macleod, Malcolm, Moher, David, Tieu, Alvin, Sikora, Lindsey, Fergusson, Dean A
Published in F1000 research

Introduction of mobile phones for use by volunteer community health workers in support of integrated community case management in Bushenyi District, Uganda: development and impleme...

by Tumusiime, David Katuruba, Agaba, Gad, Kyomuhangi, Teddy, Finch, Jan, Kabakyenga, Jerome, MacLeod, Stuart
Published in BMC health services research

Insulin-like Growth Factor Binding Proteins IGFBP3, IGFBP4, and IGFBP5 Predict Endocrine Responsiveness in Patients with Ovarian Cancer

by WALKER, Graeme, MACLEOD, Kenneth, WILLIAMS, Alistair R. W, CAMERON, David A, SMYTH, John F, LANGDON, Simon P
Published in Clinical cancer research

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records

by Thygesen, Johan H, Mizani, Mehrdad A, Banerjee, Amitava, Cooper, Jennifer, Lai, Alvina G, Sudlow, Cathie, Abbasizanjani, Hoda, Ahmed, Nida, Akbari, Ashley, Allery, Freya, Ashworth, Mark, Bacon, Seb, Ball, Steve, Banerjee, Ami, Berry, Colin, Beveridge, Jennifer, Boyle, Jon, Briffa, Norman, Buch, Maya, Canoy, Dexter, Cheema, Kate, Crallan, Rebecca, Curcin, Vasa, Curry, Gwenetta, Denholm, Rachel, Dennis, John, Denniston, Alastair, Deo, Salil, Dhillon, Baljean, Dong, Tim, Downs, Johnny, Dregan, Alexandru, Elwenspoek, Martha, Falter, Florian, Firth, Joseph, Friebel, Rocco, Gilbert, Ruth, Goldacre, Ben, Goldacre, Raph, Grieco, Luca, Handy, Alex, Hardelid, Pia, Hardy, Flavien, Hemingway, Harry, Herz, Naomi, Heyl, Johannes, Hinchliffe, Rosie, Hippisley-Cox, Julia, Hocaoglu, Mevhibe, Hollings, Sam, Inouye, Mike, Jenkins, David, Kadam, Umesh, Kallis, Costas, Khawaja, Anthony, Killick, Richard, Kinnear, Deborah, Kolamunnage-Dona, Ruwanthi, Kurdi, Amanj, Lai, Alvina, Lambarth, Andrew, Larzjan, Milad Nazarzadeh, Li, Qiuju, Lyons, Ronan, Macleod, Mary Joan, Mamouei, Mohammad, Melville, Craig, Moncusi, Marta Pineda, Morales, Daniel, Morris, Carole, Nicholson, George, Norris, Tom, Oliver, Dominic, Oluyase, Adejoke, Pierotti, Livia, Priedon, Rouven, Proudfoot, Alastair, Roberts, Brian, Rossdale, Jennifer, Samani, Nilesh, Sattar, Naveed, Schwartz, Roy, Seminog, Olena, Sinha, Shubhra, Skrypak, Mirek, Sofat, Reecha, Sun, Luanluan, Suseeladevi, Arun Karthikeyan, Tilston, George, Toit, Clea du, Torabi, Fatemeh, Watkinson, Ruth, Whiteley, William, Williams, Michelle, Williams, Richard, Withnell, Eloise, Wright, Lucy, Wu, Jinge, Wu, Jianhua, Zaccardi, Francesco
Published in The Lancet. Digital health

The effect of ABCA1 gene polymorphisms on ischaemic stroke risk and relationship with lipid profile

by Pasdar, Alireza, Yadegarfar, Ghasem, Cumming, Alastair, Whalley, Lawrence, St Clair, David, MacLeod, Mary-Joan
Published in BMC medical genetics

Abstract PR11: Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss

by Arun, Gayatri, Diermeier, Sarah, Akerman, Martin, Chang, Kung-Chi, Wilkinson, J.Erby, Hearn, Stephen, Kim, Youngsoo, MacLeod, A.Robert, Krainer, Adrian R., Norton, Larry, Brogi, Edi, Egeblad, Mikala, Spector, David L.
Published in Cancer research (Chicago, Ill.)

Radiological outcomes following surgical fixation with wires versus moulded cast for patients with a dorsally displaced fracture of the distal radius: a radiographic analysis from...

by Plant, Caroline E, Ooms, Alexander, Cook, Jonathan A, Costa, Matthew L, Dritsaki, Melina, Dakin, Helen, Jones, Jonathan, Mckee, Andrew, Smith, Kevin, Hamadto, Mohamed, Gwilym, Steve, Chesser, Tim, Candal-Couto, Jaime, Hing, Caroline, Giddin, David, Johnston, Phil, Ullah, Aamer, Williams, John, Eardley, Will, Srinivasan, Makaram, Sampalli, Sridharrao, Farrar, Mark, Roberts, Chris, Mohanty, Khitish, MacLeod, Iain, Sarda, Praveen, Elseehy, Amr, Rossiter, Nigel, Warwick, David, Peach, Chris, MacKay, David, Benson, Richard, Watts, Adam, Young, Jonathan, Shah, Feisal, Lipscombe, Stephen, Ng, Aaron, Charalambous, Charalambos P., Sheriden, Barnaby, Theivendran, Kanthan, Sanjay, Pulimamidi, Nanda, Rajesh, Bateman, Antony, Butler, Michael, Keast-Butler, Oliver, McAndrew, Andrew, Chevannes, Wystan, Kankanalu, Pradeep, Wijendra, Asanka, Fontalis, Andreas, Afifi, Hytham, Killen, Marie-Clare, Higgin, Ryan, Wignadasan, Warran, Wong, Ken, Gibson, Catherine, Beale, Harry, Jennings, Bob, Kennedy, James, Williamson, Mark, Rasidovic, Damir, Jenner, Lydia, Tadros, John B, Milner, Steve, Duncan, James, Kerr, Sally, Nordin, Louise, Weston, Matt, Payton, Olivia, Oni, Tofi, Zhao, Craig, Gill, Sukhdeep, Iqbal, Mohammad, Aneiba, Khaled, Pillai, Dilip, Hughes, Luke, Crosby, Jonathan, Whitehouse, Mike, Corbett, Thomas, Iqbal, Arshad, Buchan, Steph, Beddard, Laura, Vardhan, Venkat, Beamish, Becky, Jones, Matt, Holley, Jonathan, Morrell, Rebecca, Lerner, Robin, Draper, Kylea
Published in Bone & joint open

Abstract 4052: Direct selection of PD1+ CD39+ tumor infiltrating lymphocytes (TIL) from tumor dissociates enrich for functional tumor-reactive cells

by Pedros, Christophe, Pikor, Larissa, Fritzsche, Anna, Jilesen, Zachary K., Macleod, Bethany, Khojandi, Niloufar, Thompson, Bryant, Thayer, Matthew, Bryan, Nikolas, Carron, Emily, Ratliff, Sowbarnika S, Fraley, April, Nikota, Jake, Fisher, Robert, Delpeut, Sebastien, Kluew, Anna, Scott, Madysson, Laing, Christian, He, Leo, Bernard, Antoine, Brassard, Nathalie, Turcotte, Simon, Langer, Timothy J, Stojdl, David, Abbot, Stewart, Sennino, Barbara
Published in Cancer research (Chicago, Ill.)

Targeting PYK2 Mediates Microenvironment-Specific Myeloma Cell Death

by Meads, Mark B, Fang, Bin, Mathews, Linda, Gemmer, Jennifer, Nong, Liang, Rosado-Lopez, Ismael, Nguyen, Tuan, Ring, Jennifer E., Matsui, William, MacLeod, Robert, Weaver, David T., Pachter, Jonathan A., Hazlehurst, Lori A., Koomen, John M., Shain, Kenneth H.
Published in Blood

Identifying and understanding factors that affect the translation of therapies from the laboratory to patients: a study protocol [version 1; peer review: 1 approved, 1 approved wit...

by Lalu, Manoj M, Montroy, Joshua, Begley, C. Glenn, Bubela, Tania, Hunniford, Victoria, Ripsman, David, Wesch, Neil, Kimmelman, Jonathan, Macleod, Malcolm, Moher, David, Tieu, Alvin, Sikora, Lindsey, Fergusson, Dean A
Published in F1000 research

Identification of germ-line E-cadherin mutations in gastric cancer families of European origin

by GAYTHER, S. A, GORRINGE, K. L, MACLEOD, P, POWELL, S. M, JACKSON, C. E, PONDER, B. A. J, CALDAS, C, RAMUS, S. J, HUNTSMAN, D, ROVIELLO, F, GREHAN, N, MACHADO, J. C, PINTO, E, SERUCA, R, HALLING, K
Published in Cancer research (Chicago, Ill.)

A comparative evaluation of waist circumference, waist-to-hip ratio and body mass index as indicators of cardiovascular risk factors. The Canadian heart Health surveys

by DOBBELSTEYN, C. J, JOFFRES, M. R, MACLEAN, D. R, FLOWERDEW, G
Published in International Journal of Obesity

Abstract 16448: Role of Platelet Fragility in the Formation of Leukocyte Aggregates

by Macleod Briongos, Iain, Schroder, Bryce, Bark, David L
Published in Circulation (New York, N.Y.)

Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization

by Friedman, Jm, Adam, Shelin, Arbour, Laura, Armstrong, Linlea, Baross, Agnes, Birch, Patricia, Boerkoel, Cornelius, Chan, Susanna, Chai, David, Delaney, Allen D, Flibotte, Stephane, Gibson, William T, Langlois, Sylvie, Lemyre, Emmanuelle, Li, H Irene, MacLeod, Patrick, Mathers, Joan, Michaud, Jacques L, McGillivray, Barbara C, Patel, Millan S, Qian, Hong, Rouleau, Guy A, Van Allen, Margot I, Yong, Siu-Li, Zahir, Farah R, Eydoux, Patrice, Marra, Marco A
Published in BMC genomics

Abstract LB-227: Preclinical pharmacology and clinical efficacy of AZD9150 (ISIS-STAT3Rx), a potent next-generation antisense oligonucleotide inhibitor of STAT3

by Hong, David, Kim, Youngsoo, Younes, Anas, Nemunaitis, John, Fowler, Nathan, Hsu, Jeff, Zhou, Tianyuan, Fayad, Luis, Zhang, Nancy, Piha-Paul, Sarina, Woessner, Richard, Nadella, Murali V., Lawson, Deborah, Reimer, Corinne, Jo, Minji, Schmidt, Joanna, Xiao, Xiaokun, Greenlee, Sarah, Hung, Gene, Yamashita, Mason, Blakey, David C., Monia, Brett P., Macleod, A. Robert, Kurzrock, Razelle
Published in Cancer research (Chicago, Ill.)

Validation of the 8 th edition UICC/AJCC TNM staging system for HPV associated oropharyngeal cancer patients managed with contemporary chemo-radiotherapy

by van Gysen, Kirsten, Stevens, Mark, Guo, Linxin, Jayamanne, Dasantha, Veivers, David, Wignall, Andrew, Pang, Leo, Guminski, Alexander, Lee, Adrian, Hruby, George, Macleod, Paula, Taylor, Alon, Eade, Thomas
Published in BMC cancer

ENTPD1(CD39) expression inhibits ultraviolet radiation-induced DNA damage repair via purinergic signaling and is associated with metastasis in human cutaneous squamous cell carcino...

by Whitley, Melodi Javid, Suwanpradid, Jutamas, Lai, Chester, Jiang, Simon, Cook, Jonathan L, Zelac, Daniel E, Rudolph, Ross, Corcoran, David L, Degan, Simone, Spasojevic, Ivan, Levinson, Howard, Erdmann, Detlev, Reid, Claire, Zhang, Jennifer Y, Robson, Simon C, Healy, Eugene, Havran, Wendy L, MacLeod, Amanda S
Published in Journal of investigative dermatology

Measuring teamwork and taskwork of community-based "teams" delivering life-saving health interventions in rural Zambia: a qualitative study

by Yeboah-Antwi, Kojo, Snetro-Plewman, Gail, Waltensperger, Karen Z, Hamer, Davidson H, Kambikambi, Chilobe, MacLeod, William, Filumba, Stephen, Sichamba, Bias, Marsh, David
Published in BMC medical research methodology

Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model

by Gutschner, Tony, Hämmerle, Monika, Eißmann, Moritz, Hsu, Jeff, Kim, Youngsoo, Hung, Gene, Revenko, Alexey, Arun, Gayatri, Stentrup, Marion, Groß, Matthias, Zörnig, Martin, MacLeod, A. Robert, Spector, David L., Diederichs, Sven
Published in Cancer research (Chicago, Ill.)

Effect of Rosiglitazone on Peroxisome Proliferator-Activated Receptor γ Gene Expression in Human Adipose Tissue Is Limited by Antiretroviral Drug-Induced Mitochondrial Dysfunction

by Mallon, Patrick W. G., Sedwell, Rebecca, Rogers, Gary, Nolan, David, Unemori, Patrick, Hoy, Jennifer, Samaras, Katherine, Kelleher, Anthony, Emery, Sean, Cooper, David A., Carr, Andrew
Published in The Journal of infectious diseases