Recent advances in mass spectrometry-based approaches for proteomics and biologics: Great contribution for developing therapeutic antibodies

by Iwamoto, Noriko, Shimada, Takashi
Published in Pharmacology & therapeutics (Oxford)

Cell-penetrating peptides: classes, origin, and current landscape

by Milletti, Francesca
Published in Drug discovery today

Single B cell technologies for monoclonal antibody discovery

by Pedrioli, Alessandro, Oxenius, Annette
Published in Trends in immunology

Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics

by Panch, Sandhya R., Srivastava, Sandeep K., Elavia, Nasha, McManus, Andrew, Liu, Shutong, Jin, Ping, Highfill, Steven L., Li, Xiaobai, Dagur, Pradeep, Kochenderfer, James N., Fry, Terry J., Mackall, Crystal L., Lee, Daniel, Shah, Nirali N., Stroncek, David F.
Published in Molecular therapy

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

by Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Published in Chemistry & biology

C3-targeted therapy in periodontal disease: moving closer to the clinic

by Hajishengallis, George, Hasturk, Hatice, Lambris, John D., Apatzidou, Danae A., Belibasakis, Georgios N., Bostanci, Nagihan, Corby, Patricia M., Cutler, Christopher W., D’Aiuto, Francesco, Hajishengallis, Evlambia, Huber-Lang, Markus, Ioannidou, Effie, Kajikawa, Tetsuhiro, Kantarci, Alpdogan, Korostoff, Jonathan M., Kotsakis, Georgios A., Maekawa, Tomoki, Mastellos, Dimitrios C., Moutsopoulos, Niki M., Myneni, Srinivas, Nagelberg, Richard, Nilsson, Bo, Papapanou, Panos N., Papathanasiou, Evangelos, Potempa, Jan, Risitano, Antonio, Sahingur, S. Esra, Saito, Atsushi, Sculean, Anton, Stavropoulos, Andreas, Teles, Flavia R., Tonetti, Maurizio, Yancopoulou, Despina
Published in Trends in immunology

Characteristics of Exceptional or Super Responders to Cancer Drugs

by Prasad, Vinay, MD, MPH, Vandross, Andrae, MD
Published in Mayo Clinic proceedings

Engineered Liver Platforms for Different Phases of Drug Development

by Ware, Brenton R, Khetani, Salman R
Published in Trends in biotechnology (Regular ed.)

The challenge and promise of anti-epileptic therapy development in animal models

by Simonato, Michele, MD, Brooks-Kayal, Amy R, Prof, Engel, Jerome, Prof, Galanopoulou, Aristea S, Prof, Jensen, Frances E, Prof, Moshé, Solomon L, Prof, O'Brien, Terence J, Prof, Pitkanen, Asla, Prof, Wilcox, Karen S, Prof, French, Jacqueline A, Prof
Published in Lancet neurology

Therapeutic protein aggregation: mechanisms, design, and control

by Roberts, Christopher J
Published in Trends in biotechnology (Regular ed.)

The meningeal lymphatics: regulators of Aβ immunotherapy?

by Laaker, Collin, Fabry, Zsuzsanna
Published in Trends in immunology

Evaluation of a Fully Human, Hepatitis B Virus-Specific Chimeric Antigen Receptor in an Immunocompetent Mouse Model

by Festag, Marvin M., Festag, Julia, Fräßle, Simon P., Asen, Theresa, Sacherl, Julia, Schreiber, Sophia, Mück-Häusl, Martin A., Busch, Dirk H., Wisskirchen, Karin, Protzer, Ulrike
Published in Molecular therapy

From the European Medicines Agency to Project Orbis: new activities and challenges to facilitate UK oncology drug approval following Brexit

by Lythgoe, Mark P, Krell, Jonathan, Bower, Mark, Murphy, Ravindhi, Marriott, John, Blagden, Sarah P, Aggarwal, Ajay, Sullivan, Richard
Published in The lancet oncology

Price changes and within-class competition of cancer drugs in the USA and Europe: a comparative analysis

by Vokinger, Kerstin N, Hwang, Thomas J, Carl, David L, Laube, Yannic, Ludwig, Wolf-Dieter, Naci, Huseyin, Kesselheim, Aaron S
Published in The lancet oncology

Live virus vaccines based on a vesicular stomatitis virus (VSV) backbone: Standardized template with key considerations for a risk/benefit assessment

by Clarke, David K, Hendry, R. Michael, Singh, Vidisha, Rose, John K, Seligman, Stephen J, Klug, Bettina, Kochhar, Sonali, Mac, Lisa Marie, Carbery, Baevin, Chen, Robert T
Published in Vaccine

Early phase clinical trial played a critical role in the Food and Drug Administration–approved indications for targeted anticancer drugs: a cross-sectional study from 2012 to 2021...

by Huang, Yafang, Xiong, Weiyi, Zhao, Jingwei, Li, Wentao, Ma, Li, Wu, Hao
Published in Journal of clinical epidemiology

Electronic cigarettes for smoking cessation: a randomised controlled trial

by Bullen, Christopher, Dr, Howe, Colin, PhD, Laugesen, Murray, MBChB, McRobbie, Hayden, MBChB, Parag, Varsha, MSc, Williman, Jonathan, PhD, Walker, Natalie, PhD
Published in The Lancet (British edition)

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

by Sha, Sha, Agarabi, Cyrus, Brorson, Kurt, Lee, Dong-Yup, Yoon, Seongkyu
Published in Trends in biotechnology (Regular ed.)

A Community-Engaged Approach to Quantifying Caregiver Preferences for the Benefits and Risks of Emerging Therapies for Duchenne Muscular Dystrophy

by Peay, Holly L., MS, Hollin, Ilene, MPH, Fischer, Ryan, BA, Bridges, John F.P., PhD
Published in Clinical therapeutics

Comprehensive Analysis of the Therapeutic IgG4 Antibody Pembrolizumab: Hinge Modification Blocks Half Molecule Exchange In Vitro and In Vivo

by Yang, Xiaoyu, Wang, Fengqiang, Zhang, Ying, Wang, Larry, Antonenko, Svetlana, Zhang, Shuli, Zhang, Yi Wei, Tabrizifard, Mohammad, Ermakov, Grigori, Wiswell, Derek, Beaumont, Maribel, Liu, Liming, Richardson, Daisy, Shameem, Mohammed, Ambrogelly, Alexandre
Published in Journal of pharmaceutical sciences