Biochemical Analysis of Angelman Syndrome-associated Mutations in the E3 Ubiquitin Ligase E6-associated Protein

by Cooper, Eric M., Hudson, Amy W., Amos, Joseph, Wagstaff, Joseph, Howley, Peter M.
Published in The Journal of biological chemistry

Specificity of the BRISC Deubiquitinating Enzyme Is Not Due to Selective Binding to Lys63-linked Polyubiquitin

by Cooper, Eric M., Boeke, Jef D., Cohen, Robert E.
Published in The Journal of biological chemistry

Cardiovascular Drug Development

by Fordyce, Christopher B., MD, MSc, Roe, Matthew T., MD, MHS, Ahmad, Tariq, MD, MPH, Libby, Peter, MD, Borer, Jeffrey S., MD, Hiatt, William R., MD, Bristow, Michael R., MD, PhD, Packer, Milton, MD, Wasserman, Scott M., MD, Braunstein, Ned, MD, Pitt, Bertram, MD, DeMets, David L., PhD, Cooper-Arnold, Katharine, MPH, Armstrong, Paul W., MD, Berkowitz, Scott D., MD, Scott, Rob, MD, Prats, Jayne, PhD, Galis, Zorina S., PhD, Stockbridge, Norman, MD, PhD, Peterson, Eric D., MD, MPH, Califf, Robert M., MD
Published in Journal of the American College of Cardiology

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

by Abeshouse, Adam, Armenia, Joshua, Auman, J. Todd, Bailey, Matthew H., Baker, Laurence, Balasundaram, Miruna, Balu, Saianand, Baylin, Stephen B., Behera, Madhusmita, Benz, Christopher, Bocklage, Thèrése, Boice, Lori, Bootwalla, Moiz S., Bowlby, Reanne, Boyd, Jeff, Castro, Patricia, Cherniack, Andrew D., Chudamani, Sudha, Cooper, Lee A.D., Davis, Ian J., Demetri, George D., Demicco, Elizabeth G., Ding, Li, DiSaia, Phil, Dottino, Peter, Eschbacher, Jennifer, Fedosenko, Konstantin, Ferguson, Martin L., Gao, Qingsong, Gastier-Foster, Julie M., Gerken, Mark, Godwin, Eryn M., Gordienko, Elena, Grilley-Olson, Juneko E., Gutman, David A., Hegde, Apurva M., Heiman, David I., Helsel, Carmen, Hoadley, Katherine A., Hobensack, Shital, Hornick, Jason L., Hoyle, Alan P., Iacocca, Mary, Ittmann, Michael, Jones, Steven J.M., Kim, Jaegil, Ladanyi, Marc, Lai, Phillip H., Larsson, Erik, Lee, Sanghoon, Lehmann, Kjong-Van, Levine, Douglas A., Liu, Jia, Liu, Wenbin, Liu, Eric Minwei, Lu, Yiling, Madan, Rashna, Magliocco, Anthony, Maki, Robert G., Martinez, Cathleen, Mayo, Michael, McLellan, Michael D., Mozgovoy, Evgeny, Mungall, Andrew J., Mungall, Karen, Noble, Michael S., Olvera, Narciso, Paklina, Oxana, Paulauskis, Joseph, Penny, Robert, Perou, Charles M., Perou, Amy H., Pollock, Raphael E., Ramalingam, Suresh S., Reilly, Colleen, Reynolds, Sheila M., Roach, Jeffrey, Roszik, Jason, Sadeghi, Sara, Saksena, Gordon, Sanchez-Vega, Francisco, Sander, Chris, Schein, Jacqueline E., Shelton, Candace, Shelton, Troy, Shi, Yan, Shmulevich, Ilya, Sipahimalani, Payal, Swanson, Patricia, Tarnuzzer, Roy, Thiessen, Nina, Thorne, Leigh B., Van Tine, Brian A., Verhaak, Roel, Voronina, Olga, Wang, Jing, Wise, Lisa, Wyczalkowski, Matthew, Yau, Christina, Yellapantula, Venkata
Published in Cell

Relation Between Volume of Exercise and Clinical Outcomes in Patients With Heart Failure

by Keteyian, Steven J., PhD, Leifer, Eric S., PhD, Houston-Miller, Nancy, BSN, Kraus, William E., MD, Brawner, Clinton A., MS, O'Connor, Christopher M., MD, Whellan, David J., MD, Cooper, Lawton S., MD, Fleg, Jerome L., MD, Kitzman, Dalane W., MD, Cohen-Solal, Alain, MD, Blumenthal, James A., PhD, Rendall, David S., PA-C, Piña, Ileana L., MD, MPH
Published in Journal of the American College of Cardiology

Selective activation of PFKL suppresses the phagocytic oxidative burst

by Amara, Neri, Cooper, Madison P., Voronkova, Maria A., Webb, Bradley A., Lynch, Eric M., Kollman, Justin M., Ma, Taylur, Yu, Kebing, Lai, Zijuan, Sangaraju, Dewakar, Kayagaki, Nobuhiko, Newton, Kim, Bogyo, Matthew, Staben, Steven T., Dixit, Vishva M.
Published in Cell

Degradation of Misfolded Proteins Prevents ER-Derived Oxidative Stress and Cell Death

by Haynes, Cole M., Titus, Eric A., Cooper, Antony A.
Published in Molecular cell

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

by Zhu, Xiaofeng, Feng, Tao, Tayo, Bamidele O., Liang, Jingjing, Young, J. Hunter, Franceschini, Nora, Smith, Jennifer A., Yanek, Lisa R., Sun, Yan V., Edwards, Todd L., Chen, Wei, Nalls, Mike, Fox, Ervin, Sale, Michele, Bottinger, Erwin, Rotimi, Charles, Liu, Yongmei, McKnight, Barbara, Liu, Kiang, Arnett, Donna K., Chakravati, Aravinda, Cooper, Richard S., Redline, Susan
Published in American journal of human genetics

Variant Classification Concordance using the ACMG-AMP Variant Interpretation Guidelines across Nine Genomic Implementation Research Studies

by Amendola, Laura M., Muenzen, Kathleen, Biesecker, Leslie G., Bowling, Kevin M., Cooper, Greg M., Dorschner, Michael O., Driscoll, Catherine, Foreman, Ann Katherine M., Golden-Grant, Katie, Greally, John M., Hindorff, Lucia, Kanavy, Dona, Jobanputra, Vaidehi, Johnston, Jennifer J., Kenny, Eimear E., McNulty, Shannon, Murali, Priyanka, Ou, Jeffrey, Powell, Bradford C., Rehm, Heidi L., Rolf, Bradley, Roman, Tamara S., Van Ziffle, Jessica, Guha, Saurav, Abhyankar, Avinash, Crosslin, David, Venner, Eric, Yuan, Bo, Zouk, Hana, Jarvik, Gail P.
Published in American journal of human genetics

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research

by Manolio, Teri A., Fowler, Douglas M., Starita, Lea M., Haendel, Melissa A., MacArthur, Daniel G., Biesecker, Leslie G., Worthey, Elizabeth, Chisholm, Rex L., Green, Eric D., Jacob, Howard J., McLeod, Howard L., Roden, Dan, Rodriguez, Laura Lyman, Williams, Marc S., Cooper, Gregory M., Cox, Nancy J., Herman, Gail E., Kingsmore, Stephen, Lo, Cecilia, Lutz, Cathleen, MacRae, Calum A., Nussbaum, Robert L., Ordovas, Jose M., Ramos, Erin M., Robinson, Peter N., Rubinstein, Wendy S., Seidman, Christine, Stranger, Barbara E., Wang, Haoyi, Westerfield, Monte, Bult, Carol
Published in Cell

Intertumoral Heterogeneity within Medulloblastoma Subgroups

by Cavalli, Florence M.G., Remke, Marc, Rampasek, Ladislav, Peacock, John, Shih, David J.H., Luu, Betty, Garzia, Livia, Torchia, Jonathon, Nor, Carolina, Morrissy, A. Sorana, Agnihotri, Sameer, Thompson, Yuan Yao, Kuzan-Fischer, Claudia M., Farooq, Hamza, Isaev, Keren, Daniels, Craig, Cho, Byung-Kyu, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Grajkowska, Wieslawa A., Perek-Polnik, Marta, Vasiljevic, Alexandre, Faure-Conter, Cecile, Jouvet, Anne, Giannini, Caterina, Nageswara Rao, Amulya A., Li, Kay Ka Wai, Ng, Ho-Keung, Eberhart, Charles G., Pollack, Ian F., Hamilton, Ronald L., Gillespie, G. Yancey, Olson, James M., Leary, Sarah, Weiss, William A., Lach, Boleslaw, Chambless, Lola B., Thompson, Reid C., Cooper, Michael K., Vibhakar, Rajeev, Hauser, Peter, van Veelen, Marie-Lise C., Kros, Johan M., French, Pim J., Ra, Young Shin, Kumabe, Toshihiro, López-Aguilar, Enrique, Zitterbart, Karel, Sterba, Jaroslav, Finocchiaro, Gaetano, Massimino, Maura, Van Meir, Erwin G., Osuka, Satoru, Shofuda, Tomoko, Klekner, Almos, Zollo, Massimo, Leonard, Jeffrey R., Rubin, Joshua B., Jabado, Nada, Albrecht, Steffen, Mora, Jaume, Van Meter, Timothy E., Jung, Shin, Moore, Andrew S., Hallahan, Andrew R., Chan, Jennifer A., Tirapelli, Daniela P.C., Carlotti, Carlos G., Fouladi, Maryam, Pimentel, José, Faria, Claudia C., Saad, Ali G., Massimi, Luca, Liau, Linda M., Wheeler, Helen, Nakamura, Hideo, Elbabaa, Samer K., Perezpeña-Diazconti, Mario, Chico Ponce de León, Fernando, Robinson, Shenandoah, Zapotocky, Michal, Lassaletta, Alvaro, Huang, Annie, Hawkins, Cynthia E., Tabori, Uri, Bouffet, Eric, Bartels, Ute, Dirks, Peter B., Rutka, James T., Bader, Gary D., Reimand, Jüri, Goldenberg, Anna, Ramaswamy, Vijay, Taylor, Michael D.
Published in Cancer cell

Acute abdominal aortic dissection: Insight from the International Registry of Acute Aortic Dissection (IRAD)

by Trimarchi, Santi, MD, Tsai, Thomas, MD, Eagle, Kim A., MD, Isselbacher, Eric M., MD, Froehlich, Jim, MD, Cooper, Jeanna V., MS, Rampoldi, Vincenzo, MD, Upchurch, Gilbert R., MD
Published in Journal of vascular surgery

Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions

by Krishnan, Vaishnav, Han, Ming-Hu, Graham, Danielle L., Berton, Olivier, Renthal, William, Russo, Scott J., LaPlant, Quincey, Graham, Ami, Lutter, Michael, Lagace, Diane C., Ghose, Subroto, Reister, Robin, Tannous, Paul, Green, Thomas A., Neve, Rachael L., Chakravarty, Sumana, Kumar, Arvind, Eisch, Amelia J., Self, David W., Lee, Francis S., Tamminga, Carol A., Cooper, Donald C., Gershenfeld, Howard K., Nestler, Eric J.
Published in Cell

Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction

by Januzzi, James L., Ahmad, Tariq, Mulder, Hillary, Coles, Adrian, Anstrom, Kevin J., Adams, Kirkwood F., Ezekowitz, Justin A., Fiuzat, Mona, Houston-Miller, Nancy, Mark, Daniel B., Piña, Ileana L., Passmore, Gayle, Whellan, David J., Cooper, Lawton S., Leifer, Eric S., Desvigne-Nickens, Patrice, Felker, G. Michael, O'Connor, Christopher M.
Published in Journal of the American College of Cardiology

Multiplexed Functional Assessment of Genetic Variants in CARD11

by Meitlis, Iana, Allenspach, Eric J., Bauman, Bradly M., Phan, Isabelle Q., Dabbah, Gina, Schmitt, Erica G., Camp, Nathan D., Torgerson, Troy R., Nickerson, Deborah A., Bamshad, Michael J., Hagin, David, Luthers, Christopher R., Stinson, Jeffrey R., Gray, Jessica, Lundgren, Ingrid, Church, Joseph A., Butte, Manish J., Jordan, Mike B., Aceves, Seema S., Schwartz, Daniella M., Milner, Joshua D., Schuval, Susan, Skoda-Smith, Suzanne, Cooper, Megan A., Starita, Lea M., Rawlings, David J., Snow, Andrew L., James, Richard G.
Published in American journal of human genetics

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

by Bonsignori, Mattia, Scott, Eric, Wiehe, Kevin, Easterhoff, David, Alam, S. Munir, Hwang, Kwan-Ki, Cooper, Melissa, Xia, Shi-Mao, Zhang, Ruijun, Montefiori, David C., Henderson, Rory, Nie, Xiaoyan, Kelsoe, Garnett, Moody, M. Anthony, Chen, Xuejun, Joyce, M. Gordon, Kwong, Peter D., Connors, Mark, Mascola, John R., McGuire, Andrew T., Stamatatos, Leonidas, Medina-Ramírez, Max, Sanders, Rogier W., Saunders, Kevin O., Kepler, Thomas B., Haynes, Barton F.
Published in Immunity (Cambridge, Mass.)

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

by Carvill, Gemma L., Engel, Krysta L., Ramamurthy, Aishwarya, Cochran, J. Nicholas, Roovers, Jolien, Stamberger, Hannah, Lim, Nicholas, Schneider, Amy L., Hollingsworth, Georgie, Holder, Dylan H., Regan, Brigid M., Lawlor, James, Lagae, Lieven, Ceulemans, Berten, Bebin, E. Martina, Nguyen, John, Striano, Pasquale, Zara, Federico, Helbig, Ingo, Møller, Rikke S., von Spiczak, Sarah, Muhle, Hiltrud, Caglayan, Hande, Sterbova, Katalin, Craiu, Dana, Hoffman, Dorota, Lehesjoki, Anna-Elina, Selmer, Kaja, Depienne, Christel, Lemke, Johannes, Marini, Carla, Guerrini, Renzo, Neubauer, Bernd, Talvik, Tiina, Leguern, Eric, de Jonghe, Peter, Weckhuysen, Sarah, Barsh, Gregory S., Weckhuysen, Sarah, Meisler, Miriam, Berkovic, Samuel F., De Jonghe, Peter, Scheffer, Ingrid E., Myers, Richard M., Cooper, Gregory M., Mefford, Heather C.
Published in American journal of human genetics

Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate

by Cox, Liza L., Cox, Timothy C., Moreno Uribe, Lina M., Zhu, Ying, Richter, Chika T., Nidey, Nichole, Standley, Jennifer M., Deng, Mei, Blue, Elizabeth, Chong, Jessica X., Yang, Yueqin, Carstens, Russ P., Anand, Deepti, Lachke, Salil A., Smith, Joshua D., Dorschner, Michael O., Bedell, Bruce, Kirk, Edwin, Hing, Anne V., Venselaar, Hanka, Valencia-Ramirez, Luz C., Bamshad, Michael J., Glass, Ian A., Cooper, Jonathan A., Haan, Eric, Nickerson, Deborah A., van Bokhoven, Hans, Zhou, Huiqing, Krahn, Katy N., Buckley, Michael F., Murray, Jeffrey C., Lidral, Andrew C., Roscioli, Tony
Published in American journal of human genetics

Cardiovascular drug development: is it dead or just hibernating?

by Fordyce, Christopher B, Roe, Matthew T, Ahmad, Tariq, Libby, Peter, Borer, Jeffrey S, Hiatt, William R, Bristow, Michael R, Packer, Milton, Wasserman, Scott M, Braunstein, Ned, Pitt, Bertram, DeMets, David L, Cooper-Arnold, Katharine, Armstrong, Paul W, Berkowitz, Scott D, Scott, Rob, Prats, Jayne, Galis, Zorina S, Stockbridge, Norman, Peterson, Eric D, Califf, Robert M
Published in Journal of the American College of Cardiology

Complicated acute type B dissection: is surgery still the best option?: a report from the International Registry of Acute Aortic Dissection

by Fattori, Rossella, Tsai, Thomas T, Myrmel, Truls, Evangelista, Arturo, Cooper, Jeanna V, Trimarchi, Santi, Li, Jin, Lovato, Luigi, Kische, Stephan, Eagle, Kim A, Isselbacher, Eric M, Nienaber, Christoph A
Published in JACC. Cardiovascular interventions